Navigation Links
Human stem cells used to elucidate mechanisms of beta-cell failure in diabetes
Date:11/13/2013

henyl butyric acid reduced the ER stress and increased the amount of insulin produced by the beta cells, thereby increasing the ability to secrete insulin in response to glucose.

Direct evidence in mice, as well as circumstantial evidence in humans with both type 1 and type 2 diabetes, highlights the role of the ER stress response mechanism in the survival of insulin-producing beta cells. The ER stress response mechanisms oppose both the stress of immune assault in type 1 diabetes and the metabolic stress of high blood glucose in both types of diabetes. When the ER stress response fails cell death occurs, potentially reducing the number of insulin-producing cells.


'/>"/>

Contact: David McKeon
dmckeon@nyscf.org
212-365-7440
New York Stem Cell Foundation
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Fast-mutating DNA sequences shape early development; guided evolution of uniquely human traits
2. S14G-humanin is a new hope for Alzheimers disease
3. HIV -- Geneticists map human resistance to AIDS
4. Study maps human impacts on top ocean predators along US west coast
5. Induced pluripotent stem cells reveal differences between humans and great apes
6. Rats! Humans and rodents process their mistakes
7. Baculovirus-recognizing human cell receptor identified for the first time
8. New approach to treating human brain cancer could lead to improved outcomes
9. Superconductivity to meet humanitys greatest challenges
10. Functional genetic variation in humans: Comprehensive map published
11. DiscoveRx Announces Launch of New Human Primary Cell-Based Panels for Oncology Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... researchers and patients have hoped that embryonic stem cells ... bodycould provide insight into numerous diseases perhaps even be ... by the inability to transfer research and tools from ... because human ESCs are "primed" and slightly less plastic ... Powell, and Haoyi Wang, who are scientists in the ...
(Date:7/24/2014)... Africa in mid-July 2014, as the annual fire season ... areas of increased temperatures, are heavily sprinkled across the ... Congo (northeast), and Zambia (southeast). Thick gray smoke rises ... especially in the Democratic Republic of the Congo, strong ... fire season is an annual event in this region, ...
(Date:7/24/2014)... release is available in German . ... to recognize and respond to threats to health, and ... detailed understanding of the mechanism underlying immunologic memory, however, ... have converged to support the hypothesis that the persistence ... cells with stem-cell-like potential. Until now, there was no ...
Breaking Biology News(10 mins):Whitehead Institute researchers create 'naïve' pluripotent human embryonic stem cells 2Experiments prove 'stemness' of individual immune memory cells 2Experiments prove 'stemness' of individual immune memory cells 3
... New Orleans, LA Dr. John England, Professor and ... analyzed research findings and was responsible for the quality and ... resulting in new guidelines for treating Lou Gehrig,s disease, or ... the October 13, 2009 issue of Neurology , the ...
... knowledge and technology from the developed to the developing ... Africa. Professor Howard Atkinson (University of Leeds) will report ... at a landmark meeting at Rothamsted Research on Tuesday ... delegates. The project aims to enable African scientists to ...
... strikingly banded rocks scattered across the upper Midwest and ... past, offering clues to the environment of the early ... banded iron formations or BIFs, these ancient rocks formed ... was then the bottom of the ocean. The stripes ...
Cached Biology News:LSUHSC's England plays key role in developing new ALS treatment guidelines 2Banded rocks reveal early Earth conditions, changes 2Banded rocks reveal early Earth conditions, changes 3
(Date:7/24/2014)... PRINCETON, N.J. , July 24, 2014 /PRNewswire/ ... largest provider of regulatory and ethical review services ... acquired Alliance Biosciences. Formerly a division of ... Biosciences was the leading biosafety and biosecurity consulting ... . With this addition, WCG,s biosafety division – ...
(Date:7/24/2014)... 24, 2014   Cypher Genomics, Inc., ... of Adam Simpson as president and ... and comprehensive annotation and interpretation of individual human ... "Cypher,s technology has the potential to play ... diagnostic accuracy, optimizing therapeutic approaches and reducing adverse ...
(Date:7/23/2014)... July 23, 2014  Sangamo BioSciences, Inc. (NASDAQ: ... financial results and accomplishments. For the ... consolidated net loss of $7.0 million, or $0.10 per ... or $0.10 per share, for the same period in ... cash, cash equivalents, marketable securities and interest receivable of ...
(Date:7/23/2014)... July 23, 2014  AuraSense Therapeutics, the pioneer ... gene regulatory and immunotherapeutic agents, announced today ... AuraSense Therapeutics, executive leadership team as chief ... Prior to joining AuraSense Therapeutics, Mr. Snyder ... Officer of Cellular Dynamics International Inc., where ...
Breaking Biology Technology:WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 2Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 3Sangamo BioSciences Reports Second Quarter 2014 Financial Results 2Sangamo BioSciences Reports Second Quarter 2014 Financial Results 3Sangamo BioSciences Reports Second Quarter 2014 Financial Results 4Sangamo BioSciences Reports Second Quarter 2014 Financial Results 5Sangamo BioSciences Reports Second Quarter 2014 Financial Results 6Sangamo BioSciences Reports Second Quarter 2014 Financial Results 7Sangamo BioSciences Reports Second Quarter 2014 Financial Results 8Sangamo BioSciences Reports Second Quarter 2014 Financial Results 9AuraSense Therapeutics Appoints Biotechnology Veteran David S. Snyder as Chief Financial Officer 2
... 2011 Palatin Technologies, Inc. (NYSE Amex: PTN ) ... of shares of its common stock and warrants to purchase common ... market conditions and there can be no assurance as to whether ... actual size or terms of the offering. Roth Capital ...
... GREAT NECK, N.Y., Feb. 23, 2011 Scarguard Labs, ... of scars, psoriasis and other dermatological problems through the ... delivery system, announced today that they have received approval ... consumers throughout Canada. "We are very pleased ...
... Quanterix Corporation, a single molecule diagnostics company providing ... in vitro diagnostics markets, today announced the online publication ... Si ngle Mo lecule A rray (SiMoA™) ... straightforward measurement.  The article appears in the journal ...
Cached Biology Technology:Palatin Technologies, Inc. Announces Proposed Public Offering of Common Stock and Warrants 2Palatin Technologies, Inc. Announces Proposed Public Offering of Common Stock and Warrants 3Quanterix Announces Publication of Novel Method Expanding Single Molecule Detection Capability 2
... Intended Use: Vision Mount is formulated for covering tissue ... soluble OR alcohol insoluble end products. , ... ... chromogens such as Fast-Red or AEC that require an aqueous ...
... potent Rnase free Ribonuclease Inhibitor ... broad range of temperatures and ... not inhibit SP6, T7, or ... M-MLV reverse transcriptase or Taq ...
... kit, 110 to 220 V, enables ... doubles flow rates and valve capacity ... kit includes the Maximizer base unit, ... tubing kit, system cable 30, and ...
Mouse monoclonal antibody to QDPR - quinoid dihydropteridine reductase...
Biology Products: