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Human protein atlas will help pinpoint disease
Date:10/17/2008

on the samples. The project is generating 400 gigabytes of data every day." There is a 100-strong team working on the project, with a site due to be set up soon in India, and with antibody-producing sites in Korea and China.

"To get an idea of how far we have come, in our first year we produced on antibody," said Uhln. "This year we are hoping we can make 3000." The programme was launched in 2003, and with sufficient funding the first full version of the atlas could be available by 2014, Uhln believes.

The team has so far mapped the location of around 5000 proteins in human cells and tissues. The researchers are also investigating whether certain common cancers colon, prostate, lung and breast have different protein profiles to normal tissue. In this way new 'biomarkers' could be identified molecules which indicate that a tissue or cell is in a diseased state, which could alert doctors to the early stages of a disease.


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Contact: Mathias Uhln
Uhlen@biotech.kth.se
46-855-378-325
European Science Foundation
Source:Eurekalert

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