Navigation Links
Human adult testes cells can become embryonic-like
Date:3/23/2009

WASHINGTON, D.C. Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent embryonic-like stem cells. Researchers say that the nave cells are now potentially capable of morphing into any cell type that a body needs, from brain neurons to pancreatic tissue.

And because they produced these stem cells without the use of additional genes, the technology should be safe for human use, the researchers say in a paper published online in the journal Stem Cells and Development.

"Given these advances, and with further validation, it is possible that in the nottoo-distant-future, men could be cured of disease with a biopsy of their own testes," says the study's senior investigator, Martin Dym, PhD, a professor in the Department of Biochemistry and Molecular & Cellular Biology.

The Georgetown researchers are among the first scientists to show that human testes stem cells can become embryonic stem-like cells, and they have done this work using testis tissue from organ donors, which they say has provided enough valuable tissue to allow them to make their discoveries. While they have published their preliminary results before, they are now disclosing a new and simpler method to isolate the testes stem/progenitor cells than has not been seen in other published procedures in humans and rodents.

Being able to use adult stem cells for this type of cell-based therapy offers a number of advantages over other strategies currently being explored, says Dym. The use of embryonic stem cells is controversial because it necessitates destruction of an embryo, and pushing fully mature cells, such as skin cells, back into a stem-like state requires use of cancer genes, and has therefore been viewed as potentially risky for human treatment, he says.

The idea with this approach is that men with an incurabl
'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Gene regulation, not just genes, is what sets humans apart
2. Antioxidant overload may underlie a heritable human disease
3. Facial attraction -- choice of sexual partner shaped the human face
4. Humans fostering forest-destroying disease
5. SRMs track fire retardants in humans and environment
6. St. Jude influenza survey uncovers key differences between bird flu and human flu
7. Human derived stem cells can repair rat hearts damaged by heart attack
8. Influence of sex and handedness on brain is similar in capuchin monkeys and humans
9. Gene regulation in humans is closer than expected to simple organisms
10. Pittsburgh scientists identify human source of stem cells with potential to repair muscle
11. Researchers developing device to predict proper light exposure for human health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... N.C. , Feb. 5, 2015  Marken is ... logistics company and has launched a new marketing campaign ... Logistics Organization (CLO).  The new campaign focuses on ... patient, protocol and shipments. The first headline ... , aligns Marken,s priorities with its client,s priorities. Marken ...
(Date:2/5/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD and ... focused on the growing mobile commerce market, announces it ... Conference on January 29 th at 10:30 a.m. ... of NXT-ID will present and host a live Q&A ... and its full suite of biometric technologies. Investors can ...
(Date:1/22/2015)... Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ON), is pleased to ... State of Washington,s Department of Licensing, in ... central issuance system for driver,s licenses and identification cards to ... and development will start in January 2015, with enrollment and ...
Breaking Biology News(10 mins):Marken Launches New Patient-Centric Campaign 2CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 2CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 3Valid USA Signs Contract For Washington Driver's License Issuance 2
... (LOS ANGELES, CA) -- The Disability Rights Legal Center ... civil rights of people with disabilities, has recognized Ossur, ... non-invasive orthopaedic products and services, with the Charles D. ... of Prosthetics for Ossur Americas, accepted the award on ...
... soft drink is 20 ounces and contains 17 teaspoons of ... fruit drinks are more erosive than hydrochloric or sulfuric acidwhich ... acids found in soda and citrus juice promote tooth erosion, ... the enamel. Once tooth enamel is lost, it,s gone forever. ...
... INDIANAPOLIS Although its been over a decade since ... the blood repairing and replacing the cells that line ... EPCs are now being studied as biomarkers to assess ... agents for vascular regeneration. Researchers from ...
Cached Biology News:Disability Rights Legal Center honors Ossur 2Drink brewed tea to avoid tooth erosion 2Understanding how oxidative stress impairs endothelial progenitor cell function 2
(Date:2/26/2015)... February 26, 2015 The Pittcon ... at the Ernest N. Morial Convention Center in ... as of February 19, 2015) displaying products and ... academic, and government labs. The Exposition will offer ... not limited to, analytical chemistry; drug discovery; nanotechnology; ...
(Date:2/26/2015)... Innovation is more urgent than ever. ... of the world and transforming global markets in ... to health care, disruption is constantly underway. , ... trends shake the foundations of established business models, ... to survive the next wave of mega-change. , ...
(Date:2/26/2015)... According to a new market report published ... Crops (Corn, Soybean, Cotton and Others), Synthetic Biology-Enabled Products ... Trends and Forecast, 2013 – 2019,”the global agricultural biotechnology ... and is expected to reach USD 28,694.1 million by ... to 2019. , Demand for food production has ...
(Date:2/26/2015)... IL (PRWEB) February 26, 2015 Regis ... for the development of oncology drug substances. , Regis ... up of their new Potent Compound Suite (PCS) for ... a 36,000 square foot, cGMP facility in Morton Grove, ... cGMP manufacturing of potent compounds up to about one ...
Breaking Biology Technology:Pittcon 2015 Announces Exposition Highlights 2One Million Acts of Innovation Canada Creates Partnership with The Economist Events’ Innovation Forum 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 3Regis Extends cGMP Services to Oncology Market 2
... (Nasdaq: BCRX ) today announced that William ... Officer of BioCryst, effective July 1,2008. Dr. Sheridan ... Vice President of North American Medical Affairs at ... Tom Simon, who has been with,the Company since ...
... Technology for Lead Discovery, COPENHAGEN, June 18 ... into a drug discovery collaboration with Merck & ... drug discovery,technology to identify novel small molecule leads ... Chemetics(R) platform uses innovative DNA,labeling to allow fragment-based ...
... June 17 MEDRAD, INC., announced today,that ... new Fluorodeoxyglucose (FDG),Infusion System for Positron Emission ... PET Infusion System is the,first infusion system ... the FDG,delivery process., (Logo: http://www.newscom.com/cgi-bin/prnh/20040309/MEDRADLOGO ...
Cached Biology Technology:William P. Sheridan Appointed Chief Medical Officer of BioCryst Pharmaceuticals 2William P. Sheridan Appointed Chief Medical Officer of BioCryst Pharmaceuticals 3William P. Sheridan Appointed Chief Medical Officer of BioCryst Pharmaceuticals 4Nuevolution Announces Research and Development Collaboration with Merck & Co. Inc. 2MEDRAD Receives FDA 510(k) Clearance for FDG Infusion System 2MEDRAD Receives FDA 510(k) Clearance for FDG Infusion System 3
Endomorphin-2. Cross reactivity: Endomorphin-1 3%, Met-enkephalin <0.03%, Leu-enkephalin <0.01% and beta-Endorphin <0.01%....
... Adapted to Sf-900 II ... isolated from Spodoptera frugiperda ... cells (1). The Sf21 ... serum-free suspension culture in ...
Mouse Exodus 2 - 12kDa...
UCP1/2/3 (FL-307)...
Biology Products: