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HudsonAlpha and UAB researchers work to identify optimal treatments for ER+ breast cancer
Date:8/1/2013

omarkers, to test women with ER+ breast cancer prior to treatment, and then use this particular combination therapy for those women with the appropriate signature.

"We're also looking at the genomic data for ways to monitor patients," said Myers.

Myers and Forero explained that some patients respond favorably to the combination therapy initially but acquire a resistance over the course of treatment. "We want to catch a tumor before it starts growing again and optimally see that a patient continues a favorable progression."

In regard to patients who didn't respond well to the combination treatment in the clinical trial, Myers said those signatures might point to alternative treatment strategies.

"Funding from Komen for the Cure will allow us to carry this research full circle," said Forero, a professor of hematology and oncology at UAB. "From the original clinical trials conducted at UAB, to the genomic analysis at Hudson Alpha and back to another round of clinical investigation, this research should provide valuable insight that will allow us to tailor treatments for ER+ in the most effective way."


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Contact: Holly Ralston
hralston@hudsonalpha.org
256-508-8954
HudsonAlpha Institute for Biotechnology
Source:Eurekalert

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