Navigation Links
How your body clock avoids hitting the snooze button
Date:1/29/2009

Scientists from Queen Mary, University of London have discovered a new part of the mechanism which allows our bodyclocks to reset themselves on a molecular level.

Circadian clocks regulate the daily fluctuations of many physiological and behavioural aspects in life, and are synchronised with our surrounding environment via light or temperature cycles. Natural changes in the length of the day mean that an animal's circadian clock often has to reset itself on a molecular level, to avoid getting out of sync with the changing calendar.

Professor Ralf Stanewsky and his team from Queen Mary's School of Biological and Chemical Sciences study the circadian clocks of Drosophila, a type of fruit fly. Writing in the journal Current Biology, they report that the resetting process is governed by three factors, called Cryptochrome, Jetlag and Timeless.

The team's findings suggest that the light responses of circadian clocks are fine tuned on a molecular, by small differences in the binding affinities of clock proteins.

Professor Stanewsky explains: "A circadian photoreceptor called Cry is activated by light in the blue spectrum. Once active, Cry then becomes able to bind to a protein called Jetlag. The Jetlag protein then helps to destroy another protein called Timeless, which is used to reset the bodyclock.

"Crucially though, we found that Jetlag also helps to destroy the original photoreceptor Cry itself. This allows the Timeless protein to reaccumulate during the next day, making sure that the clock mechanism continues to tick."


'/>"/>

Contact: Sian Halkyard
s.halkyard@yahoo.co.uk
07-970-096-175
Queen Mary, University of London
Source:Eurekalert

Page: 1

Related biology news :

1. Discovery of new gene associated with diabetes risk suggests link with body clock
2. Plants grow bigger and more vigorously through changes in their internal clocks
3. Circadian clock may be critical for remembering what you learn, Stanford researchers say
4. Biological clock genes control plant growth
5. Study shows more genes are controlled by biological clocks
6. Light receptors in eye play key role in setting biological clock, study shows
7. A mammalian clock protein responds directly to light
8. Turning back the clock for Schwann cells
9. Molecular clock could predict risk for developing breast cancer
10. NYU dental professor discovers biological clock linking tooth growth to other metabolic processes
11. Systems biology approach identifies nutrient regulation of biological clock in plants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... Controller General of Immigration from Maldives Mr. Mohamed Anwar and ... international IAIR Award for the most innovative high security ePassport and eGates  ... ... Maldives Immigration Controller General, Mr. Mohamed Anwar ... right) have received the IAIR award for the "Most innovative high security ...
(Date:3/22/2017)...   Neurotechnology , a provider of high-precision ... the release of the SentiVeillance 6.0 ... recognition using up to 10 surveillance, security and ... new version uses deep neural-network-based facial detection and ... a Graphing Processing Unit (GPU) for enhanced speed. ...
(Date:3/20/2017)... 20, 2017 PMD Healthcare announces the release ... Wellness Management System (WMS), a remote, real-time lung health ... PMD Healthcare is a Medical Device, Digital Health, and ... to creating innovative solutions that empower people to improve ... focus, PMD developed the first ever personal spirometer, Spiro ...
Breaking Biology News(10 mins):
(Date:5/16/2017)... Seattle, WA (PRWEB) , ... ... ... Genomics announced today the general availability of its new ProxiMeta™ Hi-C metagenomic ... samples easily and affordably—without culturing or high-molecular-weight DNA extraction—speeding research insights at ...
(Date:5/16/2017)... Westlake Village, CA (PRWEB) , ... May 16, ... ... in personalized medicine technology and cancer diagnostics, has released its ClearID Lung Cancer ... be altered in lung cancer, this new test is designed to quickly and ...
(Date:5/16/2017)... ... (PRWEB) May 16, 2017 , ... ... Association of Orthopaedic Surgeons (CAOS), long-standing development partners Invibio Biomaterial Solutions, UK, ... spine surgery workshop to help expand knowledge of the implantation of Double ...
(Date:5/15/2017)... PA (PRWEB) , ... May 15, 2017 , ... ... insights in a presentation of “The Key Role of Specifications in Process Validation,” at ... of Philadelphia . The event will bring together leaders from the pharmaceutical and biotech ...
Breaking Biology Technology: