Navigation Links
How the common 'cat parasite' gets into the brain
Date:12/7/2012

the cat, which through its faces can infect the food that other rats might then proceed to eat. A number of studies also confirm that mental diseases like schizophrenia, depression and anxiety syndrome are more common in people with toxoplasmosis, while others suggest that toxoplasmosis can influence how extroverted, aggressive or risk-inclined an individual's behaviour is.

"We've not looked at behavioural changes in people infected with toxoplasma, as that's been dealt with by previous studies," says Dr Barragan. "Instead, we've shown for the first time how the parasite behaves in the body of its host, by which I mean how it enters the brain and manipulates the host by taking over one of the brain's neurotransmitters."

In one laboratory experiment, human dendritic cells were infected with toxoplasma. After infection, the cells, which are a key component of the immune defence, started secreting the signal substance GABA. In another experiment on live mice, the team was able to trace the movement of infected dendritic cells in the body after introducing the parasite into the brain, from where it spread and continued to affect the GABA system.

GABA is a signal substance that, amongst other effects, inhibits the sensation of fear and anxiety. Disturbances of the GABA system are seen in people with depression, schizophrenia, bipolar diseases, anxiety syndrome and other mental diseases.

"For toxoplasma to make cells in the immune defence secrete GABA was as surprising as it was unexpected, and is very clever of the parasite," says Dr Barragan. "It would now be worth studying the links that exist between toxoplasmosis, the GABA systems and major public health threats."


'/>"/>
Contact: The Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related biology news :

1. Why some strains of Lyme disease bacteria are common and others are not
2. Second most common infection in the US proving harder to treat with current antibiotics
3. Researchers discover 2 genetic flaws behind common form of inherited muscular dystrophy
4. Western aspen trees commonly carry extra set of chromosomes
5. Common food preservative may slow, even stop tumor growth
6. Study reveals how common gene mutation affects kids with autism spectrum disorders
7. Novel non-antibiotic agents against MRSA and common strep infections
8. Rare genetic disease offers insight into common cancers
9. A new light shed on genetic regulations role in the predisposition to common diseases
10. Common antifungal drug decreases tumor growth and shows promise as cancer therapy
11. Common parasite may trigger suicide attempts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... March 26, 2015 The Granite ... recreation and athletic club, today announced it has implemented ... freedom of movement for members and staff, while restricting ... comprehensive process, we selected FST,s IMID Access system because ... for our members and staff, in addition to unparalleled ...
(Date:3/23/2015)... Mass , March 23, 2015 SoundView Technology ... of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView was ... user feedback on their experience with the Wocket in multiple ... at CVS, Whole Foods and other retailers, making both debit ... Kris Tuttle also says, "If the company meets their ...
(Date:3/20/2015)... 19, 2015 Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ... - Global Strategic Business Report" report to their offering. ... Geometry in US$ Thousands. The report provides separate comprehensive analytics ... Japan , Europe , ... Rest of World. Annual estimates and forecasts are ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... WORCESTER, Mass. A research team at Worcester Polytechnic ... the National Institutes of Health (NIH) for a project ... skin cells into stem-like cells. If successful, the research ... for replacing tissue lost to injury, growing new organs, ...
... Rockefeller University, has been awarded an inaugural EUREKA grant ... aimed at exploiting a bacteria-based "nanosyringe" as a means ... The award, which provides $200,000 a year for three ... The EUREKA program Exceptional, Unconventional Research Enabling Knowledge ...
... and sleep medicine specialists from two Michigan universities ... innovative quantitative analysis, signal-processing technology and computer algorithms ... of their recent findings is that a new ... fibromyalgia patients from healthy controls. Joseph ...
Cached Biology News:NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells 2NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells 3NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells 4C. Erec Stebbins awarded prestigious EUREKA grant 2What a sleep study can reveal about fibromyalgia 2What a sleep study can reveal about fibromyalgia 3
(Date:3/30/2015)... 2015 US-Australian drug discovery company, Novogen Ltd, ... Inc., and Yale University, on March 27 released pre-clinical ... presented as an oral presentation by Professor Gil ... the 62 nd Annual Scientific Meeting of the ... CA. In both in vitro ...
(Date:3/30/2015)... Md. , March 30, 2015  Spherix ... company committed to the fostering and monetization of ... v. VTech,  Case No. 3:13-cv-03494-M and  Spherix v. ... United States District Court for the Northern District ... update regarding Spherix v. Verizon, Case ...
(Date:3/30/2015)... , March 30, 2015 ... Richmond Pharmacology ist das erste Zentrum ... am Royal Free Hospital in London ... Untersuchung eines RNAi-Therapeutikums Studienversuche an einem Patienten begonnen ... Transthyretin vermittelter Amyloidose entwickelt (ATTR), einer seltenen Herz- ...
(Date:3/29/2015)... IRVING, Texas , March 29, 2015 ... the presentation of important study data showing ... cells in 1,599 gynecologic cancer samples. Using ... tumor profiling service, researchers identified expression of ... gynecologic cancers independent of histology while its ...
Breaking Biology Technology:Yale University and Novogen Release Data on Cantrixil Mode of Action 2Yale University and Novogen Release Data on Cantrixil Mode of Action 3Yale University and Novogen Release Data on Cantrixil Mode of Action 4Spherix Provides Update on Litigation vs. VTech, Uniden and Verizon 2Spherix Provides Update on Litigation vs. VTech, Uniden and Verizon 3Caris Life Sciences' Multiplatform Tumor Profiling Technology Identifies Expression of PD-1 and PD-L1 in Gynecologic Malignancies 2Caris Life Sciences' Multiplatform Tumor Profiling Technology Identifies Expression of PD-1 and PD-L1 in Gynecologic Malignancies 3Caris Life Sciences' Multiplatform Tumor Profiling Technology Identifies Expression of PD-1 and PD-L1 in Gynecologic Malignancies 4
... Mothers Index: 4565), a biopharmaceutical company, today,announces the outcome ... current market conditions, the difficulty in raising,finance at the ... AD923 device which has necessitated a halt to the ... costs, streamline its operation and,to secure the future of ...
... the electrophysiology of sleep in a wild animal, three-toed ... day6 hours less than captive sloths did, reports an ... Research Institutes Barro Colorado Island in Panama., We are ... If we can determine the reasons for variations in ...
... Portfolio of Advanced Flow Cytometry Platforms, FRANKLIN LAKES, ... BDX ) announced today that it has acquired ... Washington,corporation based in Seattle that develops and markets advanced ... transaction were not disclosed. The acquisition,is not expected to ...
Cached Biology Technology:Sosei Announces Outcome of Strategy Review 2First electrophysical recording of sleep in a wild animal 2BD Announces Acquisition of Cytopeia 2BD Announces Acquisition of Cytopeia 3
... Kit specifically removes 20 of the most ... in preparation for further proteomics analysis. This ... proteome whether you use one- or two-dimensional ... straight to mass spectrometry. This is based ...
... specifically for western blots ,• Optically clear ... for staining western blots. The reduced size ... the disposable tray requires less dye and ... to the user. Pour spouts in each ...
... Since OligoEngine introduced the industry's first ... have constantly strived to keep these tools ... research reports in the field of RNAi. ... enhanced, and expanded RNAi design tools, OligoEngine ...
... sophisticated DNA analysis and protein analysis tasks, but ... sequence analysis product. Imagine having the ability to ... performed each time you have a new sequence, ... exactly how your output will look for each ...
Biology Products: