Navigation Links
How silver turns people blue
Date:10/30/2012

PROVIDENCE, R.I. [Brown University] Researchers from Brown University have shown for the first time how ingesting too much silver can cause argyria, a rare condition in which patients' skin turns a striking shade of grayish blue.

"It's the first conceptual model giving the whole picture of how one develops this condition," said Robert Hurt, professor of engineering at Brown and part of the research team. "What's interesting here is that the particles someone ingests aren't the particles that ultimately cause the disorder."

Scientists have known for years argyria had something to do with silver. The condition has been documented in people who (ill advisedly) drink antimicrobial health tonics containing silver nanoparticles and in people who have had alternative medical treatments involving silver. Tissue samples from patients showed silver particles actually lodged deep in the skin, but it wasn't clear how they got there.

As it turns out, argyria is caused by a complex series of chemical reactions, Hurt says. His paper on the subject, authored with Brown University colleagues Jingyu Liu, Zhongying Wang, Frances Liu, and Agnes Kane, was published online earlier this month in the journal ACS Nano.

Hurt and his team show that nanosilver is broken down in the stomach, absorbed into the bloodstream as a salt and finally deposited in the skin, where exposure to light turns the salt back into silver metal and creates the telltale bluish hue. That final stage, oddly, involves the same photochemical reaction used to develop black-and-white photographs.

From silver to salt and back again

Hurt and his team have been studying the environmental impact of silver, specifically silver nanoparticles, for years. They've found that nanosilver tends to corrode in acidic environments, giving off charged ions silver salts that can be toxic in large amounts. Hurt's graduate student, Jingyu Liu (now a postdoctoral r
'/>"/>

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Ions, not particles, make silver toxic to bacteria
2. Silver nanoparticle synthesis using strawberry tree leaf
3. Are silver nanoparticles harmful?
4. EyeLock Inc. Introduces EyeSwipe Nano TS Iris Scanning Turnstile Solution for Secure Access Control
5. NTUs new loo turns poo into power
6. Commonly used pesticide turns honey bees into picky eaters
7. New research about facial recognition turns common wisdom on its head
8. Your body doesnt lie: People ignore political ads of candidates they oppose
9. Can videogaming benefit young people with autism spectrum disorder?
10. Tigers take the night shift to coexist with people
11. New video series highlights the people who fuel Americas innovation pipeline
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Institutes of Health has awarded the Oklahoma Medical Research ... research on anthrax and the bacteria,s effects on humans. ... Ph.D., and his colleagues have studied the human immune ... Centers for Human Immunology. The original funding came soon ... the heels of the terrorist attacks of Sept. 11, ...
(Date:8/20/2014)... Biting into a chili pepper causes a burning spiciness ... Scientists exploring the chili pepper,s effect are using their ... kinds of pain, which can be caused by inflammation ... compound, which is being tested in clinical trials, in ... Tafesse and colleagues explain that decades ago, scientists had ...
(Date:8/20/2014)... therapy developed by researchers at the University of Missouri ... from a life-threatening heart condition caused by muscular dystrophy. ... Yi Lai, Ph.D., the leading author of the study ... Medicine,s Department of Molecular Microbiology and Immunology. "This is ... lead to a treatment for people with this devastating ...
Breaking Biology News(10 mins):$14.5 million grant awarded to continue anthrax studies 2Gene therapy protects mice from lethal heart condition, MU researchers find 2
... in the Journal of Trauma and Acute Care ... spinal cord-injured patients is successful not only in weaning ... to independent respiration, where they could breathe on their ... The stimulation is provided by the Diaphragm Pacing ...
... As the Endangered Species Act (ESA) celebrated its 40th anniversary at ... Wildlife Service (USFWS), was mired in controversy. At issue was a ... the List of Endangered and Threatened Wildlife and add the Mexican ... a result, the USFWS sought an independent peer review of the ...
... shape might be just as important in a biology lab ... role in the effectiveness of cells grown to repair or ... structures that enable cells to "shape up," researchers at the ... with a way to measure, and more importantly, classify, the ...
Cached Biology News:Diaphragm pacing in spinal cord injury successful in weaning patients from ventilators 2Diaphragm pacing in spinal cord injury successful in weaning patients from ventilators 3Panel issues report on gray wolf science 2Shape-sifting: NIST categorizes bio scaffolds by characteristic cell shapes 2
(Date:8/20/2014)... 20, 2014 The 6th Annual ... held on October 29-30 in San Francisco, CA. This ... and government researchers and clinicians focused on addressing and ... , In the twelve years since the sequencing of ... been introduced with pharmacogenetic information in the label and ...
(Date:8/20/2014)... Bulgaria (PRWEB) August 20, 2014 ... was released today including improvements to the enterprise ... and connectors for Lucene, SOLR and Elasticsearch. This ... for this high performance triplestore – GraphDB™ was ... interested in deploying the only mature enterprise resilient ...
(Date:8/19/2014)... Cellgen Diagnostics today ... fund a corporate lab for its genetic-based medical ... is a critical component in the move from ... implementation of personalized medicine – a more predictive, ... Indiegogo contributions will support Cellgen’s intent to develop ...
(Date:8/19/2014)... Md. , Aug. 19, 2014 CSSi, ... research industry, recently announced the formation of the company,s ... to announce the addition of Dr. William E. ... - http://photos.prnewswire.com/prnh/20140818/136957 The MCAB, ... a variety of therapeutic areas and set strategic goals ...
Breaking Biology Technology:6th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 3CSSi Appoints Dr. William E. Gannon, Jr. to Newly Formed Medical and Clinical Advisory Board 2CSSi Appoints Dr. William E. Gannon, Jr. to Newly Formed Medical and Clinical Advisory Board 3
... Car, VALLEY FORGE, Pa., Dec. 17 Good ... Diversified Racing Solutions,(DRS) to enter the NASCAR(R) Nationwide Series ... Sprint Cup Series in 2010. In the five-year,agreement, GNP ... the venture will be primarily funded by associate sponsor,relationships; ...
... Holding, Inc. (Other OTC: NHGI) today announced that ... are,posted on the OTCIQ, a service of the ... portal that provides issuers access to,innovative products and ... mitigate risk, gather market,intelligence, and inspire better corporate ...
... Maryland Stem Cell Research,Commission (Commission) today issued a ... under RFA-MD-07-3. The Commission is,soliciting nationwide applications from ... conduct basic and/or translational research on,all types of ... estimated that up to 16 fellowships will be ...
Cached Biology Technology:Good Neighbor Pharmacy Joins with Diversified Racing Solutions to Enter NASCAR Nationwide Series in 2008 2National Stem Cell Holding, Inc. Posts Company and Financial Information on the OTCIQ and Has Retained New CFO and Counsel to File Registration Statement With SEC 2Maryland Stem Cell Commission Issues Nationwide Request for Applications for New Post-Doctoral Fellowship Grants 2
... CrysScreen is a software package that ... interface for custom buffer creation, set-up ... in crystallization trials. The software helps ... in automated protein crystallography: ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Mouse monoclonal [H4B4] to LAMP2 - Lysosome Marker (Phycoerythrin) ( Abpromise for all tested applications). entrezGeneID: 3920 SwissProtID: P13473...
... Nikon's NIS-Elements revolutionizes imaging software ... automated intelligence to microscopes, cameras, components ... visualization and achiving tools. Its intuitive ... image acquisition times while providing powerful ...
Biology Products: