Navigation Links
How silver turns people blue
Date:10/30/2012

PROVIDENCE, R.I. [Brown University] Researchers from Brown University have shown for the first time how ingesting too much silver can cause argyria, a rare condition in which patients' skin turns a striking shade of grayish blue.

"It's the first conceptual model giving the whole picture of how one develops this condition," said Robert Hurt, professor of engineering at Brown and part of the research team. "What's interesting here is that the particles someone ingests aren't the particles that ultimately cause the disorder."

Scientists have known for years argyria had something to do with silver. The condition has been documented in people who (ill advisedly) drink antimicrobial health tonics containing silver nanoparticles and in people who have had alternative medical treatments involving silver. Tissue samples from patients showed silver particles actually lodged deep in the skin, but it wasn't clear how they got there.

As it turns out, argyria is caused by a complex series of chemical reactions, Hurt says. His paper on the subject, authored with Brown University colleagues Jingyu Liu, Zhongying Wang, Frances Liu, and Agnes Kane, was published online earlier this month in the journal ACS Nano.

Hurt and his team show that nanosilver is broken down in the stomach, absorbed into the bloodstream as a salt and finally deposited in the skin, where exposure to light turns the salt back into silver metal and creates the telltale bluish hue. That final stage, oddly, involves the same photochemical reaction used to develop black-and-white photographs.

From silver to salt and back again

Hurt and his team have been studying the environmental impact of silver, specifically silver nanoparticles, for years. They've found that nanosilver tends to corrode in acidic environments, giving off charged ions silver salts that can be toxic in large amounts. Hurt's graduate student, Jingyu Liu (now a postdoctoral r
'/>"/>

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Ions, not particles, make silver toxic to bacteria
2. Silver nanoparticle synthesis using strawberry tree leaf
3. Are silver nanoparticles harmful?
4. EyeLock Inc. Introduces EyeSwipe Nano TS Iris Scanning Turnstile Solution for Secure Access Control
5. NTUs new loo turns poo into power
6. Commonly used pesticide turns honey bees into picky eaters
7. New research about facial recognition turns common wisdom on its head
8. Your body doesnt lie: People ignore political ads of candidates they oppose
9. Can videogaming benefit young people with autism spectrum disorder?
10. Tigers take the night shift to coexist with people
11. New video series highlights the people who fuel Americas innovation pipeline
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... in the creation of the Santa Ana Wildfire Threat ... threat potential of the powerful, hot, dry Santa Ana ... The index was introduced Sept. 17 by the U.S. ... Gas and Electric. , The index includes four classification ... used to help fire agencies and other emergency responders, ...
(Date:9/17/2014)... Arlington engineering professor and his doctoral student have designed ... accumulate water collected from fog and dew., The device ... or deserts around the globe., Cheng Luo, professor in ... PhD candidate in the same College of Engineering department, ... edition of ACS, (American Chemical Society) Applied ...
(Date:9/17/2014)... DIEGO, Calif. (Sept. 17, 2014) A rare genetic disorder ... according to a recent joint investigation by researchers at ... San Diego. In addition to suggesting better treatment options ... more clues into the genetic underpinnings of autism., Jacobsen ... the National Institutes of Health. It occurs in a ...
Breaking Biology News(10 mins):UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2Shorebird's beak inspires UT Arlington research on water collection 2A link between Jacobsen syndrome and autism 2
... Cornell researchers have played a major role in an ... of genes of 12 closely related fruit fly species. ... from genetic adaptation to evolving immune systems -- the ... of each species., From the results of the research, ...
... CAN PROVIDE MORE SOCIETAL BENEFITS THAN GAS-POWERED AUTOS ... diesel technology or hybrid technology can provide larger ... a RAND Corporation working paper presented today. ... also found that light trucks and cars continuously ...
... major component of green tea could prove the perfect ... to a bacterial infection. In a new laboratory study, ... Research, and his colleagues have been studying the therapeutic ... a fatal immune response that kills 225,000 Americans every ...
Cached Biology News:International team compares 12 fruit fly genomes 2International team compares 12 fruit fly genomes 3RAND paper finds diesel, hybrid vehicles can provide more societal benefits than gas-powered autos 2RAND paper finds diesel, hybrid vehicles can provide more societal benefits than gas-powered autos 3RAND paper finds diesel, hybrid vehicles can provide more societal benefits than gas-powered autos 4In the laboratory, green tea proves a powerful medicine against severe sepsis 2
(Date:9/18/2014)... touch in the course of a day - ... rely on the chemical industry to turn raw ... products into valuable chemicals that are the ingredients ... Sarina Sarina, who achieved outstanding progress in driving ... temperature using light instead of fossil fuels, has ...
(Date:9/18/2014)... Whitehouse Laboratories is pleased to announce that ... has acquired an additional 4,000 square feet of dedicated ... adjacent to its current package testing facility. The official ... Whitehouse Labs is in the process of upgrading the ... testing. The prime location enables Whitehouse Labs to immediately ...
(Date:9/17/2014)... PARK, N.C. , Sept. 17, 2014  The ... presentation topics that will be featured at the conference, ... Conference Center on December 3 and 4, 2014. Researchers, ... are invited to hear the following: ... UC San Diego Skaggs School of Pharmacy ...
(Date:9/17/2014)... JH Technologies announces the ... Irvine. JH Technologies, a leader in sales and ... an expanded partnership with Leica Microsystems into the Southern ... analysis solutions will be featured at the grand opening ... showroom facility is located within the JH Technologies office’s ...
Breaking Biology Technology:Using solar energy to turn raw materials into ingredients for every day life 2Whitehouse Labs Announces Package Testing Laboratory Expansion 2Whitehouse Labs Announces Package Testing Laboratory Expansion 3Whitehouse Labs Announces Package Testing Laboratory Expansion 4In Silico Drug Discovery Conference Announces Speakers and Topics 2In Silico Drug Discovery Conference Announces Speakers and Topics 3In Silico Drug Discovery Conference Announces Speakers and Topics 4In Silico Drug Discovery Conference Announces Speakers and Topics 5In Silico Drug Discovery Conference Announces Speakers and Topics 6In Silico Drug Discovery Conference Announces Speakers and Topics 7JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 2JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 3
... fuel that can be produced from plant matter and used ... olive processing industry an opportunity to make valuable use of ... every year and sets a precedent for the recycling of ... and Granada in Spain show how this can be achieved ...
... development at the National Institute of Standards ... optical microscope to quickly and cheaply analyze ... Through-focus Scanning Optical Microscope (TSOM) imaging, the ... process control and biotechnology. , Optical microscopes ...
... Calif., Oct. 29 MannKind,Corporation (Nasdaq: MNKD ) ... November 5, 2008 at 8:00 a.m. EST., Management ... discuss the,third quarter financial results, clinical progress and other ... Presenting from the,Company will be its Chairman and Chief ...
Cached Biology Technology:Powered by olive stones? Turning waste stones into fuel 2Nanoscale dimensioning is fast, cheap with new NIST optical technique 2MannKind Corporation to Hold Third Quarter Financial Results Conference Call on November 5, 2008 2
An instrument that delivers an accurate and uniform amount of light energy to cells to photoactivate csiRNA products....
... for all types of yeast two-hybrid studies, including complex ... Choice of two bait vectors for maximum ... Triple reporter strain NMY51 ... Complete set of controls: pLexA-p53, pLexA-lamin ...
interferon-related developmental regulator 2...
Mouse Limitin MAb (Clone 183727)...
Biology Products: