Navigation Links
How proteins talk to each other
Date:9/21/2009

hich cleaved substrates are tagged at an exposed edge (N-terminal) and analyzed though mass spectrometry. The data from these assays were then matched against lists of substrates in the Protein Data Bank. Notably, caspase-3 did not cleave E. coli proteins as effectively as it did human proteins. However, when hybrid human/E. coli proteins were constructed, cleavage was greatly improved, leading researchers to conclude that caspase-3 co-evolved with its human substrates.

Because they alter the functions of other proteins, proteases like caspase-3 are critical to cell signaling. Understanding how and where they interface with target proteins enhances our ability to understand the progress of diseases.


'/>"/>

Contact: Josh Baxt
jbaxt@burnham.org
858-795-5236
Burnham Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers prolong the half-life of biopharmaceutical proteins
2. When proteins change partners
3. Disrupting a destructive duo: U of T Mississauga researchers inhibit cancer proteins
4. Bionanomachines -- proteins as resistance fighters
5. Proteins in gel
6. Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease
7. TRAPping proteins that work together inside living cells
8. Pliable proteins keep photosynthesis on the light path
9. Autopilot guides proteins in brain
10. New method for detection of phosphoproteins reveals regulator of melanoma invasion
11. New high-throughput screening technique makes probing puzzling proteins possible
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... launch in December 2014, the 1U™ app has ... to remember their usernames and passwords through replacing the antiquated ... assist people who have struggled to remember usernames and passwords, ... focuses on redefining identity, announced today that it is offering ...
(Date:12/22/2014)... and Markets ( http://www.researchandmarkets.com/research/fx4bg3/the_global ) has ... Watermarking and Fingerprinting Markets" report to their ... This insight provides an overview of ... Watermarking aims to control and monitor piracy by ...
(Date:12/19/2014)... DUBLIN , Dec. 18, 2014 Research and Markets ... of the "iPhone 5S Fingerprint Sensor - Apple/AuthenTec ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... 2012, Apple introduced the fingerprint reading feature with the ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3The Global Watermarking and Fingerprinting Markets 2iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2
... A group of Canadian and European researchers have unlocked the ... and block ovulation. The new study a collaboration between ... gnetique et biologie molculaire et cellulaire of the Universit de ... issue of the journal Genes & Development . ...
... research by Michigan State University doctoral student Jennifer Smith has ... and more importantly hunt for their food alone. ... Animal Behaviour , Smith, a student in MSU,s Department of ... living together in large, cooperative societies, they also realize that ...
... CO, USA Tectonostratigraphic terranes comprise a huge portion ... regional, discrete, fault-bound blocks containing rocks and fossils very ... resemble a collage of mixed rocks, tectonic styles, metamorphism, ... puzzle. To solve the puzzle, this new Geological Society ...
Cached Biology News:Spotted hyenas can increase survival rates by hunting alone 2
(Date:1/22/2015)... RBJ today announces the firm brokered a long-term lease totaling ... biopharmaceutical company, at Two Ledgemont Center in Lexington, ... president, and Brian Cohen , senior vice president, represented ... 95 Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... Crystal Diagnostics (CDx) Xpress System, a rapid ... AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. coli ... to as STEC or the “Big-6”) as well as Escherichia ... per 325 g of raw ground beef and raw beef ...
(Date:1/22/2015)... Controlled Substance Compliance Services (CSCS), a project managed ... legal requirements around using controlled substances in pharmaceutical research, ... their international operations expand and become increasingly complex, large ... a result of the first phase of the CSCS ...
(Date:1/22/2015)...   Cypher Genomics, Inc., the leading genome ... SQNM ), the leading molecular diagnostics company, today ... prenatal tests (NIPT). Through this agreement, Sequenom will ... advance analysis of clinically-relevant fetal sub-chromosomal variants detected ...
Breaking Biology Technology:Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Global Compliance Service for Controlled Substances to Expand to China 2Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4
... Jim Doyle announced Thursday his veto of AB 499, which ... , ,The bill would outlaw not only cloning for reproductive ... in which an embryo is created with identical DNA as ... during the first several days of development. The embryo is ...
... - A "sister park" agreement has been announced ... the Frankfurt Biotechnology Innovation Center in Frankfurt, one of ... between the two research parks was signed in Frankfurt ... Mark Bugher and Christian Garbe, managing director of the ...
... Madison, Wis. Motorists driving along the DeNeveu Creek ... notice the difference as they drive over a bridge that ... ,However, highway officials who concern themselves with the cost of ... of a much longer-lasting road. , ,Instead of having a ...
Cached Biology Technology:Doyle vetoes cloning ban 2UW-Madison engineers apply award-winning technology to road building 2
... Building on over 20 years of experience ... the Life Sciences, the Freedom EVO platform ... expansion according to future needs. Together with ... system is equipped to successfully operate genomics, ...
... ClearSpin Filter is a novel disposable spin ... clarification of bacterial lysates in plasmid purification ... a novel, disposable spin filtration device especially ... lysates in plasmid purification procedures. The neutralized ...
Comp Dim: chamber L W D 45 45 0.8 mm chamber maximum volume 1500 μL...
HybriWell seals securely to a microscope slide surface in seconds to enclose single or multiple specimens in a small reagent volume and eliminate evaporation....
Biology Products: