Navigation Links
How poor maternal diet can increase risk of diabetes -- new mechanism discovered
Date:1/6/2012

n dietary diseases and the team also found that miR-483-3p was present in elevated levels in a group of people who were born with a low birth weight.

Dr Susan Ozanne, a British Heart Foundation Senior Fellow, who led the work at the University of Cambridge, adds "It has been known for a while that your mother's diet during pregnancy plays an important role in your adult health, but the mechanisms in the body that underlie this aren't well understood. We have shown in detail how one mechanism links poor maternal diet to diabetes and other diseases that develop as we age."

Dr Ozanne and Professor Willis and their team found that miR-483-3p works by suppressing a protein called GDF3. When they studied a group of adult humans who were born with a low birth weight, they found that GDF3 protein was present at around only thirty percent of the levels found in people born at a normal weight.

Professor Willis, Director of the MRC Toxicology Unit, adds "Improving people's diets and encouraging exercise is clearly the best way to combat the epidemic of diabetes and diet-related disease which is sweeping through our society. However some people are at particular risk of these diseases, despite not looking visibly overweight. This research will hopefully allow us to help these people to take precautionary steps to reduce their likelihood of developing type 2 diabetes."

Professor Douglas Kell, Chief Executive of BBSRC said "People are continuing to live ever longer and healthier lives thanks to improvements in nutrition and healthcare. However modern diets and lifestyles are posing new challenges to which our bodies sometimes seem poorly adapted and this has caused unforeseen health problems.

"If we are to remain healthy throughout our lives and into old age it is vital that scientists work to understand our fundamental biology in the context of social and environmental changes. By identifying a mechanism that links maternal diet to
'/>"/>

Contact: Mike Davies
mike.davies@bbsrc.ac.uk
01-793-414-694
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Exposing chicks to maternal stress leads to long-term reproductive success
2. New technology aims to reduce maternal and neonatal deaths
3. Maternal health problems in Myanmar widespread
4. Effects of maternal exercise on fetal breathing movements
5. Effects of maternal exercise on fetal breathing movements
6. Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice
7. Maternal, paternal genes tug-of-war may last well into childhood
8. March of Dimes honors Dr. Gail Harrison for outstanding work in maternal-fetal nutrition
9. Exposure to young triggers new neuron creation in females exhibiting maternal behavior
10. UC Davis study confirms link between advanced maternal age and autism
11. Key nutrient in maternal diet promises dramatic improvements for people with Down syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... face the decision of whether to get a ... decision can be even more challenging. Now, a ... decisions in families of children with autism and ... parents reported the benefits of dog ownership included ... to learn responsibility. , "Children with autism spectrum ...
(Date:4/14/2014)... plant growth chamber bound for the International Space ... resupply mission may help expand in-orbit food production ... astronauts something they don,t take for granted, fresh ... to study the in-orbit function and performance of ... and its plant "pillows." The investigation will focus ...
(Date:4/14/2014)... sponges sound like creatures from a B-grade horror movie. ... the deep sea. Scientists first discovered that some sponges ... seven carnivorous species have been found in all of ... marine biologist Lonny Lundsten and two Canadian researchers describes ... deep seafloor, from the Pacific Northwest to Baja California. ...
Breaking Biology News(10 mins):Dog ownership benefits families of children with autism, MU researcher finds 2Veggie will expand fresh food production on space station 2Researchers describe 4 new species of 'killer sponges' from the deep sea 2Researchers describe 4 new species of 'killer sponges' from the deep sea 3
... National Science Foundation (NSF), bioengineers from the University of ... to characterize the thousands of control elements critical to ... mix and match these "DNA parts" in synthetic organisms ... a single designer microbe can take years to create ...
... easy as plugging it into your tee shirt or jeans, ... reporting an advance in that direction with an easier way ... e-Textiles that double as a rechargeable battery. Their report ... a monthly journal. "Wearable electronics represent a developing new ...
... applications ranging from medical devices such as MRIs to surveillance ... of 1996, Congress directed the government to sell essentially all ... government for its investment in the helium and its storage. ... from the National Research Council, assesses whether selling off the ...
Cached Biology News:NSF grant to launch world's first open-source genetic parts production facility 2NSF grant to launch world's first open-source genetic parts production facility 3NSF grant to launch world's first open-source genetic parts production facility 4
(Date:1/15/2014)... January 15, 2014 This webinar ... on nonclinical and clinical safety assessment in biosimilars. ... guide a path for biosimilar drug development, however ... of biosimilarity with regards to quality, safety and ... of biosimilar drug development and registration, development strategies ...
(Date:1/15/2014)... NC (PRWEB) January 15, 2014 ... an enhancement to its Online Web Portal for Life ... now have the ability to specify the subject matter ... nearly 50 life science sub-domains. This will help reduce ... and scientific fields, and decrease the likelihood of error. ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 ... – 11 p.m. , Location: Warrington Country Club, 1360 ... Hepatitis B Foundation, the only national nonprofit organization solely ... improving the quality of life for those affected worldwide, ... 11 at Warrington Country Club in Warrington, Pa. ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... initiated coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua ... and marketing proprietary products to serve the wound ... , In late 2012, Alliqua was restructured ... launched the company’s new strategy to become a ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... cellular biologists have made tremendous scientific advances by ... and pathways. Researchers at the University of Wisconsin-Madison ... understanding by putting the pieces back together, mathematically. ... biological engineering, developed computer models of a relatively ...
... ST. LOUIS, Feb. 6 Stereotaxis, Inc. (Nasdaq:, ... financial results for the,fourth quarter and full year ended ... market opens. The Company will host a conference call ... Eastern Time to discuss,the Company,s fourth quarter results and ...
... by $14 millionSEATTLE, Feb. 6 Cell Therapeutics, Inc. ... has engaged the services of a strategic advisory consulting ... developing strategic options for a partnership, asset divestment or ... the preclinical drug development arm of CTI, in Bresso, ...
Cached Biology Technology:Mathematical models reveal how organisms transcend the sum of their genes 2Stereotaxis Announces Fourth Quarter and Full Year 2008 Earnings Release Date and Conference Call 2CTI Seeks Strategic Alternative for Italian Facility 2CTI Seeks Strategic Alternative for Italian Facility 3
Anti-GOSR2 Monoclonal AntibodyOther Sub-Family: not assigned-Other Applications: Immunocytochemistry, Immunoprecipitation, Western Blot...
Mouse monoclonal [4A2.2] to SLC6A4 ( Abpromise for all tested applications). entrezGeneID: 6532 SwissProtID: P31645...
... The 2/3D Waver Shaker combines shaking and ... with a 330 x 330 mm stainless steel ... top incubator and cold room operation. The platform ... degree for a vigorous with action and rotation ...
Anti-DNA Polymerase a, Human Description: 50 l Research Focus: cancer & cell proliferation Storage: 4C Shipping Temperature: 4C...
Biology Products: