Navigation Links
How poor maternal diet can increase risk of diabetes -- new mechanism discovered
Date:1/6/2012

n dietary diseases and the team also found that miR-483-3p was present in elevated levels in a group of people who were born with a low birth weight.

Dr Susan Ozanne, a British Heart Foundation Senior Fellow, who led the work at the University of Cambridge, adds "It has been known for a while that your mother's diet during pregnancy plays an important role in your adult health, but the mechanisms in the body that underlie this aren't well understood. We have shown in detail how one mechanism links poor maternal diet to diabetes and other diseases that develop as we age."

Dr Ozanne and Professor Willis and their team found that miR-483-3p works by suppressing a protein called GDF3. When they studied a group of adult humans who were born with a low birth weight, they found that GDF3 protein was present at around only thirty percent of the levels found in people born at a normal weight.

Professor Willis, Director of the MRC Toxicology Unit, adds "Improving people's diets and encouraging exercise is clearly the best way to combat the epidemic of diabetes and diet-related disease which is sweeping through our society. However some people are at particular risk of these diseases, despite not looking visibly overweight. This research will hopefully allow us to help these people to take precautionary steps to reduce their likelihood of developing type 2 diabetes."

Professor Douglas Kell, Chief Executive of BBSRC said "People are continuing to live ever longer and healthier lives thanks to improvements in nutrition and healthcare. However modern diets and lifestyles are posing new challenges to which our bodies sometimes seem poorly adapted and this has caused unforeseen health problems.

"If we are to remain healthy throughout our lives and into old age it is vital that scientists work to understand our fundamental biology in the context of social and environmental changes. By identifying a mechanism that links maternal diet to
'/>"/>

Contact: Mike Davies
mike.davies@bbsrc.ac.uk
01-793-414-694
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Exposing chicks to maternal stress leads to long-term reproductive success
2. New technology aims to reduce maternal and neonatal deaths
3. Maternal health problems in Myanmar widespread
4. Effects of maternal exercise on fetal breathing movements
5. Effects of maternal exercise on fetal breathing movements
6. Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice
7. Maternal, paternal genes tug-of-war may last well into childhood
8. March of Dimes honors Dr. Gail Harrison for outstanding work in maternal-fetal nutrition
9. Exposure to young triggers new neuron creation in females exhibiting maternal behavior
10. UC Davis study confirms link between advanced maternal age and autism
11. Key nutrient in maternal diet promises dramatic improvements for people with Down syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Colo., USA - The rise of the Tibetan plateau ... Earth -- is important for both its profound effect ... this study published in GSA Bulletin , Katharine ... "clumped" isotope thermometry -- using modern and fossil snail ... basin in southwestern Tibet. , Views range widely ...
(Date:8/28/2014)... news release is available in German . ... water fish, owes its name to a striking pattern of ... types, black cells, reflective silvery cells, and yellow cells emerge ... and arrange as a multilayered mosaic to compose the characteristic ... three cell types have to interact to form proper stripes, ...
(Date:8/28/2014)... (Maximizing Access to Research Careers) Program has announced ... of America,s 27th Annual Mouse Molecular Genetics Conference ... Pacific Grove, California. These awards are meant ... and scientists from underrepresented groups into the mainstream ... the participation of young scientists at the Genetics ...
Breaking Biology News(10 mins):Snails tell of the rise and fall of the Tibetan Plateau 2Snails tell of the rise and fall of the Tibetan Plateau 3Snails tell of the rise and fall of the Tibetan Plateau 4Snails tell of the rise and fall of the Tibetan Plateau 5Snails tell of the rise and fall of the Tibetan Plateau 6Snails tell of the rise and fall of the Tibetan Plateau 7How the zebrafish gets its stripes 2How the zebrafish gets its stripes 3
... researchers in collaboration with researchers at Rutgers University ... first step in carrying out instructions contained in ... in the Nov. 17 issue of the journal ... of DNA during transcription and the effects of ...
... of medical and biological research are abuzz with ... dots. These Quantum Dots (QDs) have unique optical ... breakthrough treatments such as the detection and destruction ... website AZoNano, is a comprehensive review of the ...
... before undergoing surgery run an increased risk of ... pulmonary embolism after surgery. , Boris Mraovic, M.D., ... Center at Jefferson Medical College of Thomas Jefferson ... of nearly 6,500 hip or knee replacement surgery ...
Cached Biology News:UCLA researchers unravel a mystery about DNA 2Jefferson scientists find high glucose before surgery raises risk of dangerous complications 2
(Date:8/28/2014)... Best Sanitizers, Inc., a leader in ... industry, is asking industry professionals to prepare for fall ... E2 soap they’re currently using to the Best Sanitizers’ ... Hand hygiene is critical to fighting cross-contamination and the ... key criteria are identified to evaluate the effectiveness of ...
(Date:8/28/2014)... research platform uses a laser to measure ... stress and heating, an approach likely to ... and batteries., This new technique, called nanomechanical ... and the surface stress of microscale structures ... the merits of surface-stress influence on mechanical ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 The ability ... a culture that will allow individuals to perform at ... increasingly important for employers looking to compete in this ... are embracing this trend, as the sector increasingly focuses ... a company, which will have real results on the ...
(Date:8/28/2014)... Sterlitech is proud to announce that ... stable of products . These additional products ... include membrane filters with surface charges. , ... for our membrane process testing equipment, and correspondingly, a ... membranes,” explains Sterlitech President Mark Spatz. “The addition ...
Breaking Biology Technology:Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2
... 18 Burrill & Company, a San Francisco-based global ... Private Equity, Merchant Banking and Media, is pleased to ... Managing Director, Merchant Banking. Shawn will assist clients in ... raising transactions. In addition, Shawn will make an important ...
... LONDON, June 18 , ... UK Distribution Rights , Speciality ... pharmaceutical company, is pleased to announce that it will ... the,UK and Ireland, as of the 1st July 2009. ...
... of Oregon physicists have successfully landed a one-two punch ... helium and then dosing its perimeter with a laser ... a near standstill. The findings, published in ... that exploits special quantum properties and in precision-measurements for ...
Cached Biology Technology:Shawn Cross Joins Burrill Merchant Banking 2Shawn Cross Joins Burrill Merchant Banking 3SEP Signs REGURIN(R) Deal 2SEP Signs REGURIN(R) Deal 3SEP Signs REGURIN(R) Deal 4SEP Signs REGURIN(R) Deal 5SEP Signs REGURIN(R) Deal 6
... supply, with temperature probe, 100-120 and 220-240 V, ... mA, and 400 W. The temperature probe is ... 90 degrees C during electrophoresis. Built-in infrared capability ... instructions are provided. Dimensions are 27.5 x 34 ...
The stirbar is used in the buffer tank of the Trans-Blot Plus cell to maintain uniform conductivity and temperature during electrophoretic transfer. Dimensions are 3.5 x 0.5 in....
... cooling coil, Trans-Blot cell, provides ... high-intensity, and extended electrophoretic transfer ... Trans-Blot cell. Use of the ... to an external water recirculator, ...
Criterion staining and blotting trays are plastic trays designed for staining one or two Criterion gels or performing western blot detection. The trays have a working capacity of up to 500 ml. Suppli...
Biology Products: