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How our cells cope with toxic small molecules
Date:1/30/2013

s not the case, and that the cell is likely to constantly produce damaged metabolites, which have to be eliminated or repaired." A deficiency in metabolite repair can lead to fatal disease in humans.

The field of 'metabolite damage-control' is still in its infancy and biochemists are just starting to understand how the cell repairs damaged metabolites. This suggests that many metabolite damage-control systems remain to be discovered. "I hope that scientists who read this review will be convinced that metabolite repair is an important aspect of cell metabolism", says Linster. "It should inspire researchers to look for yet unidentified reactions and thereby improve our understanding of the extent of metabolite damage-control and the physiological importance thereof."


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Contact: Carole Linster
carole.linster@uni.lu
003-524-666-446-231
University of Luxembourg
Source:Eurekalert

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