Navigation Links
How our brain networks: Research reveals white matter 'scaffold' of human brain
Date:2/11/2014

For the first time, neuroscientists have systematically identified the white matter "scaffold" of the human brain, the critical communications network that supports brain function.

Their work, published Feb. 11 in the open-source journal Frontiers in Human Neuroscience, has major implications for understanding brain injury and disease. By detailing the connections that have the greatest influence over all other connections, the researchers offer not only a landmark first map of core white matter pathways, but also show which connections may be most vulnerable to damage.

"We coined the term white matter 'scaffold' because this network defines the information architecture which supports brain function," said senior author John Darrell Van Horn of the USC Institute for Neuroimaging and Informatics and the Laboratory of Neuro Imaging at USC.

"While all connections in the brain have their importance, there are particular links which are the major players," Van Horn said.

Using MRI data from a large sample of 110 individuals, lead author Andrei Irimia, also of the USC Institute for Neuroimaging and Informatics, and Van Horn systematically simulated the effects of damaging each white matter pathway.

They found that the most important areas of white and gray matter don't always overlap. Gray matter is the outermost portion of the brain containing the neurons where information is processed and stored. Past research has identified the areas of gray matter that are disproportionately affected by injury.

But the current study shows that the most vulnerable white matter pathways the core "scaffolding" are not necessarily just the connections among the most vulnerable areas of gray matter, helping explain why seemingly small brain injuries may have such devastating effects.

"Sometimes people experience a head injury which seems severe but from which they are able to recover. On the other hand, some p
'/>"/>

Contact: Suzanne Wu
suzanne.wu@usc.edu
213-740-5552
University of Southern California
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. TGen study uncovers possible genetic markers in breast cancer that spreads to the brain
2. Your brain is fine-tuning its wiring throughout your life
3. Stanford researchers discover how brain regions work together, or alone
4. Making your brain social
5. Study shows autistic brains create more information at rest
6. Cc to the brain: How neurons control fine motor behavior of the arm
7. New molecule protects brain from detrimental effects linked to diabetes and high blood sugar
8. Permanent changes in brain genes may not be so permanent after all
9. Cannabis during pregnancy endangers fetal brain development
10. How does the brain create sequences?
11. Brain on autopilot
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How our brain networks: Research reveals white matter 'scaffold' of human brain
(Date:2/5/2015)... Calif. , Jan. 27, 2015 /PRNewswire/ ... provider of globally deployed, innovative test solutions ... announced the delivery of its TS-323 ... Space Systems Company (LMSSC). GENASYS is a ... demands of mission-critical applications that require performance ...
(Date:2/5/2015)... MOUNTAIN VIEW, Calif. , Feb. 3, 2015 ... screen printer technology, demand from industries such as ... the global market for surface mount technology (SMT) ... manual equipment to automatic control will push the ... glue dispensers will remain steady as glue dispensers ...
(Date:1/22/2015)... 2015 Technology Showcase, Hall E -   EyeLock Inc. ... announced it will showcase its EyeLock ID technology integrated in ... of Energy,s Oak Ridge National Laboratory (ORNL) at ... iris identity authentication technology is being used to validate the ...
Breaking Biology News(10 mins):Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3
... prevention is worth a pound of cure" can easily ... Because taking off extra weight is an almost insurmountable ... especially childhood, is crucial to realizing optimal long-term health. ... being breastfed might predispose a person to being lean, ...
... The putative skull of Saint Bridget (Birgitta) of Sweden ... is probably not authentic. A new study conducted at Uppsala ... Saint Bridget and her daughter Catherine (Katarina), is not from ... not from the time period when Bridget and Catherine lived. ...
... research of Dr. Doris Taylor was achieved recently when ... agreement with Miromatrix Medical Inc. Dr. Taylor,s research ... that it had created a beating animal heart in ... the promise of one day enabling the replacement of ...
Cached Biology News:Later introduction of baby foods related to lower risk of obesity later in life 2The putative skull of St. Bridget can be questioned 2U of Minnesota finalizes license agreement to form start-up company based on Doris Taylor research 2
(Date:2/26/2015)... MENLO PARK, Calif. , Feb. 26, 2015 /PRNewswire/ ... has released the latest version of the Governance ... organizations accomplish governance, risk and compliance (GRC) tasks across ... has also been updated to help customers better align ... Organizations of the Treadway Commission ) requirements. In response ...
(Date:2/26/2015)... 26, 2015 On behalf of biotech ... companies, Wilentz, Goldman & Spitzer, P.A. (Wilentz) ... lawsuit against Genewiz Inc. in excess of $10 million. ... GenScript’s trade secrets, and that it improperly hired one ... an order denying motions for judgment notwithstanding the verdict, ...
(Date:2/26/2015)... 26, 2015 BioEnterprise today announced that ... more than $2 billion in growth funding during the ... investors, strategic sources, state – including the Ohio Third ... $2 billion has been raised in the past five ... heels of the BioEnterprise Midwest Healthcare Growth Capital ...
(Date:2/26/2015)... February 26, 2015 Innovation is ... emerging from unexpected parts of the world and ... From agriculture to manufacturing to health care, disruption ... environmental realities and socio-political trends shake the foundations ... key ingredient for CEOs to survive the next ...
Breaking Biology Technology:Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 3Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 2Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 3More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 2More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 3More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 4One Million Acts of Innovation Canada Creates Partnership with The Economist Events’ Innovation Forum 2
... of Energy,s Lawrence Berkeley National Laboratory and the ... world,s first all-integrated sensor circuit based on nanowire ... different crystalline materials. Their method can be used ... , Nanostructures made with specific chemical, electronic, ...
... Revenues - a record $35.5 million vs. $24.7 million in Q2 2007 ... - an increase of 43.4%, Q2 2008 Diluted Net Income per Share - ... ... Q2 2007 Q2 2008 New Bookings of $49.0 million vs. $34.5 million in Q2 2007, ...
... Conference, August 3-8, CHICAGO, Aug. 4 Criminal ... to reduce the spread of the virus.,Instead, it increases ... burdening women and other vulnerable groups who,are unable to ... violence,according to a commentary in the August issue of ...
Cached Biology Technology:A first in integrated nanowire sensor circuitry 2A first in integrated nanowire sensor circuitry 3A first in integrated nanowire sensor circuitry 4eResearchTechnology Reports Second Quarter 2008 Results 2eResearchTechnology Reports Second Quarter 2008 Results 3eResearchTechnology Reports Second Quarter 2008 Results 4eResearchTechnology Reports Second Quarter 2008 Results 5eResearchTechnology Reports Second Quarter 2008 Results 6eResearchTechnology Reports Second Quarter 2008 Results 7eResearchTechnology Reports Second Quarter 2008 Results 8eResearchTechnology Reports Second Quarter 2008 Results 9JAMA Commentary Opposes Criminal Punishment for HIV Exposure/Transmission 2JAMA Commentary Opposes Criminal Punishment for HIV Exposure/Transmission 3
...
... recognizes 30% of IgM-rheumatoid factor ... does not cross-react with IgM, IgA, ... nor with pooled F(Ab)2 fragments. This ... to detect rheumatoid factor. Product Category: ...
...
Human VEGF R2 (KDR) MAb (Clone 89106)...
Biology Products: