Navigation Links
How memory is read out in the fly brain
Date:7/8/2011

ehavior of the flies was not altered, when certain nerve cells were deactivated only while the flies recalled the associated memory. The responsible nerve cells, known as MB-V2 cells, had to be intact in order for the flies to fully retrieve the associative memory. These cells were, however, not important for the flies' ability to associate odor and electrical stimulus or to stabilize the formed memory. The results thus indicated that MB-V2 cells are involved in a memory 'read-out' pathway.

Alternative pathways of memory processing

Prior to this experiment, it was known that olfactory information is processed in the lateral horn of the fly's brain. As a result of such processing, certain behavior, such as innate odor avoidance or approach, can be released. In contrast, the mushroom body is the site in the fly brain, where a positive or negative value is given to the odor information. Here, the neutral odor is associated with the negative sensation of the electric stimulus to form an aversive odor memory. The neurobiologists' results, which were now published in Nature Neuroscience, showed that MB-V2 cells receive information from the mushroom body and that they, in turn, relay to the nerve cells in the lateral horn.

"For the first time, we demonstrated the function of this alternative pathway via which a learned odor directs avoidance behavior for the memory recall", Hiromu Tanimoto, one of the two leaders of the study, explains. Instinctive behavior, such as the avoidance of certain odors, operates directly via the lateral horn and, as such, remains unperturbed by deactivation of the MB-V2 cells.

"The identification of these cells and the role they play in recalling the contents of the memory are significant milestones on the way to gaining an understanding of how memory guides animal behavior", Tanimoto explains. Perhaps one day, science will thus be able to explain why our brains sometimes get stuck, when trying
'/>"/>

Contact: Stefanie Merker, Ph.D.
merker@neuro.mpg.de
49-898-578-3514
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Fly guy makes memory breakthrough
2. SUNY Downstate researchers find that memory storage molecule preserves complex memories
3. Developer of advanced computing memory, father of biochemical engineering, and innovative engineering educators win highest engineering honors of 2009
4. DREAM: 1 gene regulates pain, learning and memory
5. Crabs memory of pain confirmed by Queens academic
6. Computer simulations explain the limitations of working memory
7. Caltech scientists reveal how neuronal activity is timed in brains memory-making circuits
8. UT San Antonio researcher wins $917,000 from NIH to study memory
9. Researchers see evidence of memory in the songbird brain
10. UTSA psychologist awarded $1 million for memory research
11. Short stressful events may improve working memory
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How memory is read out in the fly brain
(Date:7/13/2015)... 13, 2015 Synaptics Inc. (NASDAQ: ... solutions, today announced sampling of ClearPad ® ... integration (TDDI) product targeting smartphones and tablets. This ... Synaptics , best-in-class touch controller IP and ... developed in the company,s Japan Design Center. TDDI ...
(Date:7/9/2015)... Calif. , July 9, 2015  Unchained ... today announcing its acquisition of Avid Nano. Avid ... light scattering (DLS) systems.    Also ... smallest, fastest and easiest to use protein sizing ... that measures a protein,s hydrodynamic size, size distribution, ...
(Date:7/8/2015)... , July 8, 2015  Trovagene, Inc. (NASDAQ: ... diagnostics, today announced the launch of a study ... Precision Cancer Monitoring℠ (PCM) technology for predicting response ... or a combination of the novel immunotherapy agents ... a PD-1 inhibitor. The 50-patient study will be ...
Breaking Biology News(10 mins):Synaptics Announces Sampling of Second Generation TDDI Solutions 2Synaptics Announces Sampling of Second Generation TDDI Solutions 3Unchained Labs just can't get enough, acquires Avid Nano, rocks out the new pUNk! 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 4
... greenhouse-gas emissions in comparison to fossil fuels. In the ... highlight a new study that factors in environmental costs ... short. The authors urge governments to be far more ... are more environmentally friendly than fossil fuels., Because fossil ...
... - The crystal structure of a molecule from a primitive ... more about the evolution of life from the simple to ... fungus protein bound to an RNA molecule, scientists from Purdue ... able to visualize how life progressed from an early self-replicating ...
... - Investigators at the University of Alabama at,Birmingham ... a,chemical ,messenger, leading to autoimmune disorders like rheumatoid,arthritis ... occurring chemical interleukin 17,(IL-17), an immunity protein. ... in autoimmune and,inflammatory responses, aside from its commonly ...
Cached Biology News:Scientists find missing evolutionary link using tiny fungus crystal 2Protein's new role discovered in autoimmune disease 2
(Date:7/29/2015)... Inc. (NYSE: BIOA ) today announced that ... resigned.  The Company has hired Andrew Ashworth , ... 2014, as full time interim CFO and has launched ... Andy Ashworth began his employment today, to overlap ... was the Company,s CFO from September 2011 to December ...
(Date:7/29/2015)... ... July 29, 2015 , ... ... supplier, announces the launch of their 2nd generation cell therapy POD® design. The ... CT, but it also represents a new POD® design. , “G-CON first ...
(Date:7/29/2015)... CHICAGO , July 29, 2015  AmnioChor Inc., ... cell technology, is very pleased to announce that the ... has agreed to invest in their seed round ... OmniBank placental tissue storage capabilities. AmnioChor,s ... placenta, and the human stem cells living within those ...
(Date:7/29/2015)... July 29, 2015  Indivior PLC (LON: INDV) today ... nasal spray was accepted and received Priority Review by ... treatment of opioid overdose. This naloxone nasal spray comes ... for optimal absorption into the nasal mucosa. 1 ... so individuals may be better equipped to help an ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3G-CON Manufacturing Launches Their 2nd Generation Cell Therapy Cleanroom POD® 2G-CON Manufacturing Launches Their 2nd Generation Cell Therapy Cleanroom POD® 3The Musculoskeletal Transplant Foundation Agrees to Invest in AmnioChor 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 3Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 4Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 5
... Wright, Co-Chair of the Alliance for Biosecurity and ... before the House Labor, Health and Human Services, ... of developing drugs, vaccines and other medical countermeasures ... catastrophic health emergencies. Effective medical countermeasures for many ...
... to Better Serve Asia-Pacific Clinical Trial Enrollment ConcernsNEWTON, ... leader in patient recruitment for clinical trials, has ... G.K., in Osaka, Japan. The company will be ... device companies, as well as CROs and SMOs, ...
... Sopherion Therapeutics, LLC, a biopharmaceutical company focused ... announced that it completed enrollment in its pivotal ... in metastatic HER-2-overexpressing breast cancer. This is ... product in combination with the current standard of ...
Cached Biology Technology:Alliance for Biosecurity Testifies Before Congress on Funding for Medical Countermeasure Development 2Forward-Thinking Patient Recruitment Company Poised to Create Bridges Between Japanese Clinical R&D Industry and Global Clinical Trial Marketplace 2Forward-Thinking Patient Recruitment Company Poised to Create Bridges Between Japanese Clinical R&D Industry and Global Clinical Trial Marketplace 3Sopherion Therapeutics Announces Completion of Enrollment in Phase III Study of Myocet in Metastatic Breast Cancer 2Sopherion Therapeutics Announces Completion of Enrollment in Phase III Study of Myocet in Metastatic Breast Cancer 3
... Gel/Mount is an aqueous-based mounting medium ... tissue sections. Gel/Mount is especially recommended ... allophycocyanin or FluoroBlue. It can also ... such as fluorescein (FITC), Rhodamine (TMRITC) ...
...
... Rabbit polyclonal to JNK1 (phospho T183 + ... an internal domain containing phosphorylated T183/Y185. Reactivity ... Rat. Not yet tested in other species. ... subgroups, including the ERK, JNK, and p38 kinases. ...
Dako Target Retrieval Solution, Citrate pH 6 (x 10) For more information, please visit Dako' web-site. EU regulatory status: CE US regulatory status: IVD...
Biology Products: