Navigation Links
How heat helps to treat cancer
Date:8/8/2012

Research at Bangor University has identified a switch in cells that may help to kill tumors with heat. Prostate cancer and other localized tumors can be effectively treated by a combination of heat and an anti-cancer drug that damages the genes. Behind this novel therapy is the enigmatic ability of heat to switch off essential survival mechanisms in human cells. Although thermotherapy is now more widely used, the underlying principles are still unclear.

In a recent publication in the Journal of Cell Science (http://jcs.biologists.org/content/early/2012/07/10/jcs.104075.abstract) researchers based in the School of Biological Sciences report now that heat modulates these survival systems by promoting the production of a novel protein. Intriguingly, this protein is only produced when elevated temperatures activate a gene that hides inside another gene.

The leader of the Genome Biology group, Dr Thomas Caspari says: "The discovery is reminiscent of a Russian doll were a set of smaller wooden figures is placed inside a larger doll. The existence of such hidden genes may explain why the human genome has a much smaller number of genes than initially expected. Our work may also help to improve heat-treatment of cancer for the benefit of patients. This research success was a real team effort made possible by the generous funding from Cancer Research Wales and the European Leonardo DaVinci Program."


'/>"/>

Contact: Press Office, Bangor Uni
press@bangor.ac.uk
01-248-388-293
Bangor University
Source:Eurekalert

Page: 1

Related biology news :

1. Protein jailbreak helps breast cancer cells live
2. Newly found protein helps cells build tissues
3. New iPad, iPhone app helps mariners avoid endangered right whales
4. University of Minnesota invention helps advance reliability of alternative energy
5. New analysis helps guide use of erlotinib in advanced non-small cell lung cancer
6. Gene signature helps identify risk of relapse in lung cancer patients
7. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
8. Scripps research scientists find anticonvulsant drug helps marijuana smokers kick the habit
9. New musical pacifier helps premature babies get healthy
10. Worlds largest release of comprehensive human cancer genome data helps speed discoveries
11. New Tool Helps Drug Developers Optimize Their Research and Target Development for Better Results and a Stronger Competitive Edge
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... -- Market Research Future published a half cooked research report on ... and Service Market is expected to grow over the CAGR of ... ... Mobile Biometric Security and Service Market is increasing ... authentication and security from unwanted cyber threats. The increasing use of ...
(Date:12/8/2016)... Calif. , Dec. 8, 2016  Singulex, Inc., ... Molecule Counting technology, entered into a license and supply ... serving science. The agreement provides Singulex access to Thermo ... Europe is used to diagnose systemic ... United States to aid in assessing the ...
(Date:12/7/2016)... , December 7, 2016 According to a new market ... Software Tool (Facial Expression, Voice Recognition), Service, Application Area, End User, And Region ... to grow from USD 6.72 Billion in 2016 to USD 36.07 Billion by ... Continue Reading ... MarketsandMarkets ...
Breaking Biology News(10 mins):
(Date:12/9/2016)... According to a new market research report "Oligonucleotide Synthesis Market ... (Research, PCR, Gene, DNA, NGS, Diagnostic, RNAI), End user (Academic, Pharmaceutical, ... is expected to reach USD 2.20 Billion by 2021 from USD ... forecast period. Continue Reading ... ...
(Date:12/8/2016)...  OncoSec Medical Incorporated ("OncoSec") (NASDAQ: ... immunotherapies, today announced financial results for the fiscal ... delivering on our commitment to address an unmet ... are pleased with the early clinical response data ... are focused on advancing our lead program – ...
(Date:12/8/2016)... 8, 2016  Renova™ Therapeutics, a biotechnology company ... and type 2 diabetes, announced that it has ... virus (AAV) vector developed in the laboratory of ... Stanford University. The company plans to use this ... product pipeline. "Early research has ...
(Date:12/8/2016)... OXFORD, England , December 8, 2016 /PRNewswire/ ... (OGT), das Unternehmen für Molekulargenetik, erweitert seine Palette ... SureSeq myPanel™ NGS Custom FH Panels, das ein ... Hypercholesterinämie (FH) ermöglicht. Das Panel bietet eine Erkennung ... Number Variations (CNV) mit einem einzigen kleinen Panel ...
Breaking Biology Technology: