Navigation Links
How heat helps to treat cancer
Date:8/8/2012

Research at Bangor University has identified a switch in cells that may help to kill tumors with heat. Prostate cancer and other localized tumors can be effectively treated by a combination of heat and an anti-cancer drug that damages the genes. Behind this novel therapy is the enigmatic ability of heat to switch off essential survival mechanisms in human cells. Although thermotherapy is now more widely used, the underlying principles are still unclear.

In a recent publication in the Journal of Cell Science (http://jcs.biologists.org/content/early/2012/07/10/jcs.104075.abstract) researchers based in the School of Biological Sciences report now that heat modulates these survival systems by promoting the production of a novel protein. Intriguingly, this protein is only produced when elevated temperatures activate a gene that hides inside another gene.

The leader of the Genome Biology group, Dr Thomas Caspari says: "The discovery is reminiscent of a Russian doll were a set of smaller wooden figures is placed inside a larger doll. The existence of such hidden genes may explain why the human genome has a much smaller number of genes than initially expected. Our work may also help to improve heat-treatment of cancer for the benefit of patients. This research success was a real team effort made possible by the generous funding from Cancer Research Wales and the European Leonardo DaVinci Program."


'/>"/>

Contact: Press Office, Bangor Uni
press@bangor.ac.uk
01-248-388-293
Bangor University
Source:Eurekalert

Page: 1

Related biology news :

1. Protein jailbreak helps breast cancer cells live
2. Newly found protein helps cells build tissues
3. New iPad, iPhone app helps mariners avoid endangered right whales
4. University of Minnesota invention helps advance reliability of alternative energy
5. New analysis helps guide use of erlotinib in advanced non-small cell lung cancer
6. Gene signature helps identify risk of relapse in lung cancer patients
7. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
8. Scripps research scientists find anticonvulsant drug helps marijuana smokers kick the habit
9. New musical pacifier helps premature babies get healthy
10. Worlds largest release of comprehensive human cancer genome data helps speed discoveries
11. New Tool Helps Drug Developers Optimize Their Research and Target Development for Better Results and a Stronger Competitive Edge
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2015)... -- higi, a leading cloud-based consumer engagement platform that provides ... their communities around health and wellness, announced today the ... ... convenient vehicle to receive validated health information from consumers. ... API will allow higi,s trusted partners, on a user ...
(Date:4/2/2015)... Germany , April 2, 2015 ... fingerprint tests DERMALOG by far outperforms the strongest ... always maintaining high accuracy, the system is capable ... Hence, the speed proves up to be ten ... faster than its runner-up performance.      ...
(Date:4/1/2015)... , April 1, 2015   Medisafe ™, ... million users across iOS and Android ... begun integrating biofeedback into the platform to allow patients ... outcomes. For the first time, patients will be able ... a dose impacts important biometrics, such as glucose levels ...
Breaking Biology News(10 mins):higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2
... at UCLA,s Jonsson Comprehensive Cancer Center have modified a common ... Tomography (PET), an advance that will allow them to model ... to new therapies. The discovery, published June 8, 2008 ... enables scientists to monitor the immune system at the ...
... Communication,Intelligence Corporation (the "Company") (OTC Bulletin Board: CICI), ... process,automation in the financial industry and the recognized ... has closed a financing, on,June 5, 2008, led ... As part of the financing, the Company borrowed ...
... ANN ARBOR, Mich.---Developing fundamental math and mechanics to explain ... could open doors to a new frontier in biology, ... and engineers will gather in Woods Hole, Mass. June ... Mechanics. The University of Michigan is leading the organization ...
Cached Biology News:UCLA researchers develop new PET scanning probe that will allowing monitoring of the immune system 2UCLA researchers develop new PET scanning probe that will allowing monitoring of the immune system 3Communication Intelligence Corporation Closes $3.6 Million Financing 2Communication Intelligence Corporation Closes $3.6 Million Financing 3Communication Intelligence Corporation Closes $3.6 Million Financing 4Forum to focus on math and mechanics behind life processes 2Forum to focus on math and mechanics behind life processes 3
(Date:5/5/2015)... May 5, 2015  Tikcro Technologies Ltd. (OTCQB: ... to continue trading on OTCQB  Marketplace, the market ... Marketplace allows for a continuous public market for ... have real-time quotes and market information on us ... OTCQB Marketplace includes U.S. and international companies in ...
(Date:5/5/2015)... 2015  Renova™ Therapeutics, a biopharmaceutical company developing ... other chronic diseases, has engaged RAND Health Advisory ... reflect the healthcare patterns of multiple advanced heart ... used to characterize the impact the company,s lead ... groups of patients and the overall health care ...
(Date:5/5/2015)... 2015 ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") (NYSE ... President and Chief Executive Officer, will present live ... DATE:  Thursday, May 7, 2015     TIME:  11:30 am ET/8:30 ... click the red "register/ watch presentations" button ... event where investors are invited to ask the ...
(Date:5/5/2015)... WASHINGTON, D.C., USA (PRWEB) May 05, 2015 ... export regulations covering a wide range of key photonics ... are hampering global competitiveness of U.S. industry. To help ... webinar on 12 May on the proposed ... governs the commodities covered by International Traffic in Arms ...
Breaking Biology Technology:Tikcro Technologies Announces Approval to Continue Trading on OTCQB 2RAND Health Advisory Services modeling heart failure patient outcomes to inform potential impact of Renova Therapeutics lead product candidate 2RAND Health Advisory Services modeling heart failure patient outcomes to inform potential impact of Renova Therapeutics lead product candidate 3ImmunoCellular Therapeutics to Webcast Live at VirtualInvestorConferences.com on May 7 2Comments needed now from photonics industry on revisions of U.S. export rules 2Comments needed now from photonics industry on revisions of U.S. export rules 3Comments needed now from photonics industry on revisions of U.S. export rules 4
... -- UW-Madison Civil and Environmental Engineering professor ... have both received approximately $40,000 from the John ... innovative teaching approaches. , ,Cramer, professor Hussain Bahia, ... Media Services will convert the three-credit Materials for ...
... Wis. -- Paragon Development Systems is poised for ... office to house the company's 24/7 service desk, the ... which is an IT infrastructure services provider, officially unveiled ... the space at 361 Blettner Blvd. in June. , ...
... has joined the board of directors of Neurognostics, ... which spun out of the Medical College of Wisconsin ... services , ,Silva-Craig is the president and chief operating ... 2001. Emageon provides medical image management software ...
Cached Biology Technology:UW professors get grants to engage technology for course delivery 2PDS sees Madison facility as launchpad for growth 2PDS sees Madison facility as launchpad for growth 3