Storing blood can alter the blood's physical characteristics, and if those include changes in density, this technique may be able to detect blood doping, Grover says.
Researchers in Manalis' lab are now investigating the densities of other types of cells, and are starting to work on measuring single cells as they grow over time specifically cancer cells, which are characterized by uncontrolled growth.
"Understanding how density of individual cancer cells relates to malignant progression could provide fundamental insights into the underlying cellular processes, as well as lead to clinical strategies for treating patients in situations where molecular markers don't yet exist or are difficult to measure due to limited sample volumes," Manalis says.
|Contact: Caroline McCall|
Massachusetts Institute of Technology