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How Salmonella forms evil twins to evade the body's defenses
Date:12/8/2011

e presence within the Salmonella clonal population. In an animal or human, anatomical location determines which type will fare better during each stage of the infection.

The researchers also found that Salmonella strains that lack the YdiV protein are unable to fully repress the production of flagellin. These mutant strains are less infectious. Looking at the other side of the host-pathogen struggle, mutant mice that couldn't launch pyroptosis in response to flagellin were more susceptible to serious Salmonella infections.


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Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

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