House Ear Institute, TGen and Belgian researchers identify gene in age-related he...(n important role in presbycusis but unti...)

Date:12/2/2008

n important role in presbycusis, but until now genetic research has lagged behind compared to other important diseases," said Guy Van Camp, director of the Hereditary Deafness Laboratory and professor, University of Antwerp, Belgium. "The identification of GRM7 is a very exciting result, as it may provide insights in the development of the disease."

The study participants were Caucasian, ages 53 to 67, and the samples were collected at eight centers in six nations throughout Europe from population registries or audiological consultations. The team of investigators analyzed the samples and identified genetic risks.

In the lab, the research team used Affymetrix GeneChip Human Mapping 500K to score markers across the entire genome of more than 2,000 samples.

Friedman said the next step is developing a laboratory model to test pharmaceuticals for possible treatment of presbycusis in the future.

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Contact: Steve Yozwiak syozwiak@tgen.org 602-343-8704 The Translational Genomics Research Institute Source:Eurekalert

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