Navigation Links
Hot sauce ingredient reduces 'beer belly' fat as a weight-loss surgery alternative
Date:5/9/2012

BOSTON, MAAccording to research from Brigham and Women's Hospital (BWH), the ingredient that gives hot sauce its heat could play a role in the future of weight loss.

Ali Tavakkoli, MD, BWH Department of Surgery, and his team have published a study investigating whether two surgeries called vagal de-afferentationwhich uses capsaicin, the component responsible for the chili pepper's burning sensationand vagatomy can achieve weight loss and reduce the risk of obesity-related diseases with fewer side effects when compared to today's bariatric surgical options.

The study is published in the May issue of Digestive Diseases and Sciences. The study is accompanied by an editorial by Edward A. Fox, PhD, Purdue University.

After testing the two surgeries in the lab, the researchers found that vagotomy significantly reduced total body fat, as well as visceral abdominal fatthe "beer belly" fat that pads the spaces between abdominal organs. Vagal de-afferentation also reduced these fats, but to a lesser degree.

However, according to the researchers, the reduction is still remarkable.

"The reduction in visceral fat is particularly important," said Tavakkoli. "High visceral fat volume is a marker of obesity and obesity-related diseases, such as diabetes. Preferentially lost visceral fat after vagal de-afferentation highlights the potential for this procedure."

Vagotomy involves removing the vagus nerve, which sends information between the gut and the brain. Vagal de-afferentation also involves the vagus nerve. But rather than removing the nerve completely, surgeons use capsaicin to destroy only certain nerve fibers.

Capsaicin destroys the nerve fibers that take signals from the gut to the brain, leaving intact the nerve fibers that send signals in the opposite direction, from the brain to the gut.

Between the two surgeries, vagal de-afferentation is associated with fewer side effects.

The researchers note that more work needs to be done on whether these surgeries can be used on humans, and whether capsaicin could be applied directly to human vagal fibers. The study results, however, provide promise of what the future can hold.

"As demand for surgeries that reduce weight and obesity-related diseases increases, procedures that can achieve success in a less invasive fashion will become increasingly important," said Tavakkoli. "This is an important and developing surgical discipline, especially as diabetes rates soar worldwide, and people try to find effective therapies to fight this epidemic."


'/>"/>
Contact: Marjorie Montemayor-Quellenberg
617-534-2208
Brigham and Women's Hospital
Source:Eurekalert

Related biology news :

1. New infant formula ingredients boost babies immunity by feeding their gut bacteria
2. New fermented soy ingredient containing S-equol significantly reduced hot flash frequency
3. Medical researchers make important research link between active ingredient in saffron and MS
4. Unlisted ingredients in teas and herbal brews revealed in DNA tests by high school students
5. New delivery system for Viagra ingredient
6. Studies focus on feed ingredients effects on levels of E. coli O157:H7 in cattle
7. Recipe for family mealtimes calls for 3 ingredients in the right amounts
8. More asteroids could have made lifes ingredients
9. Ginger is key ingredient in recipe for conserving stag beetles
10. Grape ingredient resveratrol increases beneficial fat hormone
11. Birch bark ingredient comes with many metabolic benefits
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... , June 9, 2016 ... deploy Teleste,s video security solution to ensure the safety of ... during the major tournament Teleste, an ... systems and services, announced today that its video security solution ... to back up public safety across the country. The ...
(Date:6/3/2016)... , June 3, 2016 ... Management) von Nepal ... und Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, ... führend in der Produktion und Implementierung von ... der Ausschreibung im Januar teilgenommen, aber Decatur ...
(Date:6/2/2016)... --  The Weather Company , an IBM Business (NYSE: ... in which consumers will be able to interact with IBM ... voice or text and receive relevant information about the product ... have long sought an advertising solution that can create a ... and valuable; and can scale across millions of interactions and ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... The immunohistochemistry (IHC) market is projected ... of 7.3% during the forecast period of 2016 to 2021 dominated ... accounted for the largest share of immunohistochemistry (IHC) market, by end ... , , ... market spread across 225 pages, profiling 10 companies and supported with ...
(Date:11/30/2016)... /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the Company") ... to announce the formation of EyGen, Ltd. a ... assets through proof of concept. EyGen,s lead asset ... Pharmaceuticals Limited and being developed for topical ophthalmic ... segment diseases. This agent has the potential to ...
(Date:11/30/2016)... BEIJING , Nov. 30, 2016 Novogene ... services and solutions with cutting edge next-generation sequencing (NGS) ... a USD $75 Million [515 Million RMB] B round ... Capital Management ( Shenzhen ) Co., Ltd. ... Innovation") and Shanghai Sigma Square Investment Center LP ("Sigma ...
(Date:11/30/2016)... Woburn, MA (PRWEB) , ... November 30, 2016 ... ... broadband light sources for advanced technology applications, introduces the 5th generation, ultra-bright, Laser-Driven ... the highly successful Laser-Driven Light Source (LDLS™) technology, the EQ-77 offers higher radiance ...
Breaking Biology Technology: