Navigation Links
Hot sauce ingredient reduces 'beer belly' fat as a weight-loss surgery alternative

BOSTON, MAAccording to research from Brigham and Women's Hospital (BWH), the ingredient that gives hot sauce its heat could play a role in the future of weight loss.

Ali Tavakkoli, MD, BWH Department of Surgery, and his team have published a study investigating whether two surgeries called vagal de-afferentationwhich uses capsaicin, the component responsible for the chili pepper's burning sensationand vagatomy can achieve weight loss and reduce the risk of obesity-related diseases with fewer side effects when compared to today's bariatric surgical options.

The study is published in the May issue of Digestive Diseases and Sciences. The study is accompanied by an editorial by Edward A. Fox, PhD, Purdue University.

After testing the two surgeries in the lab, the researchers found that vagotomy significantly reduced total body fat, as well as visceral abdominal fatthe "beer belly" fat that pads the spaces between abdominal organs. Vagal de-afferentation also reduced these fats, but to a lesser degree.

However, according to the researchers, the reduction is still remarkable.

"The reduction in visceral fat is particularly important," said Tavakkoli. "High visceral fat volume is a marker of obesity and obesity-related diseases, such as diabetes. Preferentially lost visceral fat after vagal de-afferentation highlights the potential for this procedure."

Vagotomy involves removing the vagus nerve, which sends information between the gut and the brain. Vagal de-afferentation also involves the vagus nerve. But rather than removing the nerve completely, surgeons use capsaicin to destroy only certain nerve fibers.

Capsaicin destroys the nerve fibers that take signals from the gut to the brain, leaving intact the nerve fibers that send signals in the opposite direction, from the brain to the gut.

Between the two surgeries, vagal de-afferentation is associated with fewer side effects.

The researchers note that more work needs to be done on whether these surgeries can be used on humans, and whether capsaicin could be applied directly to human vagal fibers. The study results, however, provide promise of what the future can hold.

"As demand for surgeries that reduce weight and obesity-related diseases increases, procedures that can achieve success in a less invasive fashion will become increasingly important," said Tavakkoli. "This is an important and developing surgical discipline, especially as diabetes rates soar worldwide, and people try to find effective therapies to fight this epidemic."

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Related biology news :

1. New infant formula ingredients boost babies immunity by feeding their gut bacteria
2. New fermented soy ingredient containing S-equol significantly reduced hot flash frequency
3. Medical researchers make important research link between active ingredient in saffron and MS
4. Unlisted ingredients in teas and herbal brews revealed in DNA tests by high school students
5. New delivery system for Viagra ingredient
6. Studies focus on feed ingredients effects on levels of E. coli O157:H7 in cattle
7. Recipe for family mealtimes calls for 3 ingredients in the right amounts
8. More asteroids could have made lifes ingredients
9. Ginger is key ingredient in recipe for conserving stag beetles
10. Grape ingredient resveratrol increases beneficial fat hormone
11. Birch bark ingredient comes with many metabolic benefits
Post Your Comments:
(Date:10/13/2015)... Research and Markets ( ) has announced the ... Market - Estimation & Forecast (2015-2020)" report to ... --> The biometric market value is anticipated to ... in 2020 at an estimated CAGR of 16.47% from ... . Growing digitization in the government sector is expected ...
(Date:10/12/2015)... -- NXTD ) ("NXT-ID" or the "Company"), a ... reports on the recent SNS Future in Review Conference in ... NXTD ) ("NXT-ID" or the "Company"), a biometric authentication company ... recent SNS Future in Review Conference in Park ... NXTD ) ("NXT-ID" or the "Company"), a biometric authentication ...
(Date:10/8/2015)... October 8, 2015 NXT-ID, ... "Company"), a biometric authentication company focused on the ... Wocket® smart wallet announces that revenues for the ... $410,000 compared with $113,00 for the three months ... months ended September 30, 2015 were approximately $520,000. ...
Breaking Biology News(10 mins):
(Date:10/13/2015)... ... ... Proove Biosciences, a commercial and research leader ... Medicine of the University of Southern California (USC) Pain Center to study ... Clinical Objectives Linking Genotypic and Phenotypic Association with Pain Outcomes) is one of ...
(Date:10/12/2015)... Calif. and BRUSSELS , Oct. ... (Euronext Brussels: UCB) today presented additional findings from an exploratory ... The findings were presented today in an oral plenary ... (ASBMR) 2015 Annual Meeting in Seattle . ... --> The small exploratory sub-study data showed ...
(Date:10/12/2015)... , Oct. 12, 2015 This report covers ... include cell type, products, applications, end-user markets and geographic ... HIGHLIGHTS The global cell expansion market generated revenue ... to reach revenues of $9.7 billion in 2015 and ... rate (CAGR) of 17.8% from 2015 to 2020. ...
(Date:10/12/2015)... octubre de 2015 El 8 de octubre, ... récord en el congreso con su declaración acerca del ... Plasma Awareness Week (IPAW), que se celebrará del 11 ... la Plasma Protein Therapeutics Association (PPTA) y ... , Aumentar la concienciación mundial acerca de la donación ...
Breaking Biology Technology: