Navigation Links
Host change alters toxic cocktail
Date:3/11/2011

beetles contain the enzyme salicyl alcohol oxidase in strikingly large amounts. The scientists labeled it SAO-W (W: willow). Using corresponding DNA sequence data they isolated and characterized the SAO-B (B: birch) encoding gene from birch feeders. They found that the amino acid sequences of both enzymes are 97 percent identical. However, SAO-B has become inactive because 27 amino acids at the beginning of the polypeptide chain are missing. This was confirmed after heterologous expression in an insect cell culture and subsequent functional tests. Further studies on the defensive glands of birch feeders showed that the amount of messenger RNA (mRNA) of the SAO-B gene was reduced by 1000 times compared to willow beetles; the protein and its enzyme activity were below the detection level. The lack of enzyme activity is caused by a mutation in the SAO-B gene located in the area of the second exon/intron junction. The mutation is responsible for changes in mRNA processing, so-called alternative splicing, which leads to the loss of 27 amino acids in the SAO-B enzyme.

The scientists conclude that, originally, Chrysomela lapponica used willows exclusively as host plants and later shifted to birch trees as well. "It is still unclear, whether the gene mutation has enabled the host plant shift from willow to birch or whether it was adapted in the course of evolution after the shift to birch had occurred," says Wilhelm Boland, the leader of the study. Genetic analysis of further SAO genes from Chrysomela leaf beetle species will allow a better understanding of these processes. [JWK, AO]


'/>"/>

Contact: Wilhelm Boland
boland@ice.mpg.de
49-364-157-1200
Max Planck Institute for Chemical Ecology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Pathology study tracks uterine changes with mifepristone
2. Mapping human vulnerability to climate change
3. Virginia Tech shares in grant to study effects of climate change on southern pine forests
4. Examining climate change effects on wheat
5. Climate change affecting food safety
6. NIFA announces grants to study the effects of climate change on agricultural and forest production
7. Invasive plants can create positive ecological change
8. Cross-border conservation vital to protect birds in a climate-change world
9. Wolverines threatened by climate change, earlier springs
10. Wolverine population threatened by climate change
11. Island-scale study reveals climate-change effects
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Host change alters toxic cocktail
(Date:7/31/2014)... Hibiscus flowers- they are an iconic symbol of ... in the landscape. Some, like Hawaii,s State Flower- ... Only a relatively few botanists and Hawaiian conservation ... and intriguing related group of plants known as ... Brother of Hibiscus species are in fact highly ...
(Date:7/31/2014)... NXT-ID, Inc., (NXTD: OTCQB) a biometric authentication company ... and consumers wanting to learn more about its  ... on-air today, July 31 st . ... featured in a segment of NewsWatch, a weekly ... the History Channel, FYI Network today. ...
(Date:7/30/2014)... uses reversible epigenetic processes to regulate its genes, and ... a picture of the genome regulation taking place in ... Genome Biology and illustrates how the truffle ... genes,. The authors say this may shed light on ... Black truffles (Tuber melanosporum), also known as Prigord truffles, ...
Breaking Biology News(10 mins):Brother of Hibiscus is found alive and well on Maui 2NXT-ID's Next Generation Biometric Smart Wallet Featured on NewsWatch Consumer Show on the History Channel and FYI Network Today, July 31st 2NXT-ID's Next Generation Biometric Smart Wallet Featured on NewsWatch Consumer Show on the History Channel and FYI Network Today, July 31st 3How black truffles deal with the jumpers in their genome 2
... tiny luminescent particles made of semiconductors, hold promise ... doctors were to use them in humans, quantum ... and possible toxicity. Scientists at Emory University ... a way around those limitations by exploiting a ...
... Calif.) The apparent success of a case in which ... marrow transplant comes as no surprise to Gerhard Bauer, a ... more than 10 years on a similar cure for AIDS ... patient with stem cells that have been engineered to resist ...
... discovered that management efforts intended to assist migrations of ... fish populations. Juveniles that are transported downstream on boats ... breeding grounds, reducing their survivorship and altering adaptations in ... place for over three decades to improve the survival ...
Cached Biology News:'Strained' quantum dots show new optical properties 2UC Davis researchers exploring gene therapy to fight AIDS 2UC Davis researchers exploring gene therapy to fight AIDS 3Transporting juvenile salmon hinders adult migration 2Transporting juvenile salmon hinders adult migration 3
(Date:7/31/2014)... SHENZHEN, China , July 31, 2014 ... an Irys™System by BGI , the ... enable comprehensive exploration of human structural variation (SV) and ... interest, including those where no reference exists. In addition, ... methods for multiplexing on the Irys System, enabling significantly ...
(Date:7/31/2014)... Toronto, Canada (PRWEB) July 31, 2014 ... with some of the first transcriptome-wide analyses appearing ... a standard assay for RNA measurement. In the ... high throughput, more specific, work with smaller input ... special tissues (eg, blood samples). On the bioinformatics ...
(Date:7/31/2014)... The Kidney Cancer Association (KCA) has established a CNN iReport ... News. , Bill Bro, KCA CEO, says, “We’re pleased ... international news organization. When we began using iReport last month, ... program highlights news of an enzyme that is lost in ... Kidney Cancer News also presents a report on outcomes from ...
(Date:7/30/2014)... PARIS , July 30, 2014  Regeneron ... NYSE: SNY) today announced that the Companies intend to ... pediatric disease priority review voucher in connection with the ... review voucher entitles the holder to designate a BLA ... review from the filing date instead of the standard ...
Breaking Biology Technology:BioNano Genomics Announces the Purchase of the Irys System by BGI 2BioNano Genomics Announces the Purchase of the Irys System by BGI 3BioNano Genomics Announces the Purchase of the Irys System by BGI 4The Evolution of RNA-Sequencing, Upcoming Live Webinar August 22 hosted by Xtalks 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6
... most conductive material, discovered in 2004 at the University ... Novoselov, has the potential to revolutionize material science. , ... scientists the Nobel Prize for Physics last year and ... plans for a 50m graphene research hub to be ...
... Novelda AS announced today two new antennas for its CMOS Impulse ... on a Sinuous Antenna geometry. The antenna itself consists of two ... the antenna itself; the lower PCB is a balancing network. The ... can be lowered by attaching a lens. This lens is built ...
... AlloSource, ( www.allosource.org ) a leading developer, ... use in surgical procedures around the world, is among ... Denver Business Journal,s inaugural awards program. With concerns ... employee benefits, the Denver Business Journal sought ...
Cached Biology Technology:Graphene's 'Big Mac' creates next generation of chips 2Wideband Antenna for Novelda Nanoscale Impulse Radar 2AlloSource Named One of Denver's Healthiest Employers 2AlloSource Named One of Denver's Healthiest Employers 3
... Platypus Contact Printing Kit contains choice ... with series of 100 / 200 micron ... or 200 um x 10 mm lines, ... 20, 40 or 60 nm and pitch ...
Request Info...
Sterile glass 5 mm beads that make spreading bacterial and yeast cultures easy. Can be washed, autoclaved and reused....
... are supplied as 10X concentrated solutions. REact Buffer ... of the REact buffers and one 250 microl ... four 1 ml vials of REact 1 Buffer ... four 1 ml vials of REact 3 Buffer ...
Biology Products: