Navigation Links
Hormone therapy could enhance the therapeutic effect of head and facial bone grafts
Date:11/20/2013

Bone grafts, which are used to treat head injuries and birth defects, still pose major medical challenges, but scientists are reporting progress toward a new hormone therapy that could improve the outcomes of these surgeries. Their study, which was conducted on mice, appears in the ACS journal Molecular Pharmaceutics.

Zulma Gazit at Cedars-Sinai Medical Center, Edward Schwarz from Rochester University and colleagues note that surgeons perform nearly 100,000 head and facial bone-grafting procedures every year to treat bone loss from disease, birth defects or traumatic injuries. Though this kind of reconstructive surgery dates back to ancient times, the options for implant materials remain limited. Doctors can remove bone from another part of a patient's body or use lab-made materials, but these methods can lead to serious complications. Currently, one of the preferred alternatives is to use bone grafts received from tissue banks, but they often don't join with the bone they're supposed to fix. Preliminary studies have shown that parathyroid hormone (PTH), a drug approved by the U.S. Food and Drug Administration to treat osteoporosis, helps repair fractures in long bones. The team wanted to see if PTH also would help head and facial donor grafts fuse into place.

They tested the hormone in mice with skull defects that they implanted with donor grafts. Daily short-term PTH treatment improved bone formation around the grafts and prevented scar tissue, which can interfere with graft integration, from forming. "These findings will aid in the development of an attractive bone graft, which is readily available, for use in craniofacial reconstruction," they say.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Hormones impact stress, memories, and understanding social cues
2. Gut hormone test predicts individual efficacy of gastric bypass
3. Study reveals potential role of love hormone oxytocin in brain function
4. Arg-Phe-amide-related peptides influence gonadotropin-releasing hormone neurons
5. Prohormonesdirect.com Offers in Depth OxyELITE Pro Reviews
6. Prohormonesdirect.com Discusses the Man of Steel Workout Plan
7. Calcium and vitamin D help hormones help bones
8. US Peptides Discusses HGH and Growth Hormone Releasing Peptides and How They Affect Performance
9. A newly discovered hormone makes ovaries grow
10. Discovery of new hormone opens doors to new type 2 diabetes treatments
11. Nearly half of veterans found with blast concussions might have hormone deficiencies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
(Date:4/6/2017)... April 6, 2017 Forecasts by ... Document Readers, by End-Use (Transportation & Logistics, Government & ... Gas & Fossil Generation Facility, Nuclear Power), Industrial, Retail, ... Are you looking for a definitive report ... ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
Breaking Biology News(10 mins):
(Date:9/19/2017)... ... 2017 , ... The latest generation of the AutoBlock, from ... for metals digestion—the addition of acids and reagents. The accessory fits any size ... ideal for any laboratory performing their own unique metals digestion method. , ...
(Date:9/19/2017)... CA (PRWEB) , ... September 19, 2017 , ... VetStem Biopharma ’s CEO and ... Riordan PA, PhD in Riordan’s new book "Stem Cell Therapy: A Rising Tide". Dr. ... 14 years. They bonded over an interest in the potential of stem cell therapy ...
(Date:9/19/2017)... SAN FRANCISCO , Sept. 19, 2017 ... Management Solutions (VLMS) is pleased to announce the strategic ... VTI to provide clients with validation services using the ... a partner, VTI will provide clients with efficient and ... be a marketing partner for the ValGenesis VLMS system. ...
(Date:9/19/2017)... ... September 19, 2017 , ... ... (NYS DFS) cybersecurity regulations have transitioned into full force and effect. ... in the state (“Covered Entities”) to conduct an annual, professional, comprehensive cybersecurity ...
Breaking Biology Technology: