Navigation Links
Hormone therapy could enhance the therapeutic effect of head and facial bone grafts
Date:11/20/2013

Bone grafts, which are used to treat head injuries and birth defects, still pose major medical challenges, but scientists are reporting progress toward a new hormone therapy that could improve the outcomes of these surgeries. Their study, which was conducted on mice, appears in the ACS journal Molecular Pharmaceutics.

Zulma Gazit at Cedars-Sinai Medical Center, Edward Schwarz from Rochester University and colleagues note that surgeons perform nearly 100,000 head and facial bone-grafting procedures every year to treat bone loss from disease, birth defects or traumatic injuries. Though this kind of reconstructive surgery dates back to ancient times, the options for implant materials remain limited. Doctors can remove bone from another part of a patient's body or use lab-made materials, but these methods can lead to serious complications. Currently, one of the preferred alternatives is to use bone grafts received from tissue banks, but they often don't join with the bone they're supposed to fix. Preliminary studies have shown that parathyroid hormone (PTH), a drug approved by the U.S. Food and Drug Administration to treat osteoporosis, helps repair fractures in long bones. The team wanted to see if PTH also would help head and facial donor grafts fuse into place.

They tested the hormone in mice with skull defects that they implanted with donor grafts. Daily short-term PTH treatment improved bone formation around the grafts and prevented scar tissue, which can interfere with graft integration, from forming. "These findings will aid in the development of an attractive bone graft, which is readily available, for use in craniofacial reconstruction," they say.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Hormones impact stress, memories, and understanding social cues
2. Gut hormone test predicts individual efficacy of gastric bypass
3. Study reveals potential role of love hormone oxytocin in brain function
4. Arg-Phe-amide-related peptides influence gonadotropin-releasing hormone neurons
5. Prohormonesdirect.com Offers in Depth OxyELITE Pro Reviews
6. Prohormonesdirect.com Discusses the Man of Steel Workout Plan
7. Calcium and vitamin D help hormones help bones
8. US Peptides Discusses HGH and Growth Hormone Releasing Peptides and How They Affect Performance
9. A newly discovered hormone makes ovaries grow
10. Discovery of new hormone opens doors to new type 2 diabetes treatments
11. Nearly half of veterans found with blast concussions might have hormone deficiencies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/26/2014)... feeding patients through a tube, in an intensive care ... practice of a certain amount of feeding per hour ... to a volume-based system, which calls for a certain ... a system was found to be effective in ICU ... the American Society for Parenteral and Enteral Nutrition,s (A.S.P.E.N.) ...
(Date:8/26/2014)... Unregulated trash burning around the globe is pumping far ... records. A new study led by the National Center ... of the world,s garbage is burned in such fires, ... health and climate change. , The new study provides ... pollutants such as particulates, carbon monoxide, and mercury that ...
(Date:8/26/2014)... an increased risk of autism among children of ... reflect the known increased risk associated with severe ... online publication in Molecular Psychiatry , investigators ... while a diagnosis of autism spectrum disorder was ... antidepressants during pregnancy than in those with no ...
Breaking Biology News(10 mins):Trash burning worldwide significantly worsens air pollution 2Trash burning worldwide significantly worsens air pollution 3Study calls into question link between prenatal antidepressant exposure and autism risk 2Study calls into question link between prenatal antidepressant exposure and autism risk 3
... New Rochelle, NY, October 30, 2009Sponsored by ... by BioConferences International, Inc., GREENBioPharma is the first ... and technologies available for sustainable life science organizations. ... and methods, but also on the economic rationales ...
... the fight against the deadly Hendra virus following the development ... lives of people who become infected with the virus. ... demonstrated that administering human monoclonal antibodies after exposure to Nipah ... from challenge in a disease model. According to CSIRO,s ...
... around the world are becoming more like the highly diverse ... has led UOG professors Thomas Marler and Seyda Turk-Smith to ... of teaching to a group of learners with a range ... and learning more about how my psychology research can be ...
Cached Biology News:Breakthrough in fight against Hendra virus 2Multicultural education focus of new UOG publication 2
(Date:8/26/2014)... San Diego, CA, and Bellingham, WA (PRWEB) August ... nanoscience and optical engineering, visions for next-generation wearable ... Light 2015 among numerous highlights at this year’s ... in the San Diego, California, Convention Center. More ... suppliers last week attended conferences, courses, an exhibition, ...
(Date:8/26/2014)... and REHOVOT, Israel , August 26, ... 3D printing specialist, Replica 3DM, supports NHS hospitals with surgery ...   - Performing surgery on 3D ... times; improves patient recovery and provides an effective aid for ... Ltd. (Nasdaq: SSYS ), a global leader ...
(Date:8/26/2014)... CA (PRWEB) August 26, 2014 The ... USD 8,020.1 million by 2020, according to a new ... personalized medicine and theranostics, and the subsequent introduction of ... factors driving market growth over the next six years. ... chronic diseases such as cancer, coupled with disease triggering ...
(Date:8/26/2014)... Aug. 26, 2014  Guardant Health, a healthcare ... oncology diagnostic products, has been recognized today by ... Technology Pioneer . As an innovator in non-invasive, ... companies across a wide variety of industries and ... Guardant360 ® , Guardant Health,s first commercially ...
Breaking Biology Technology:Brighter, Busier SPIE Optics + Photonics Draws International Crowd to San Diego 2Brighter, Busier SPIE Optics + Photonics Draws International Crowd to San Diego 3Brighter, Busier SPIE Optics + Photonics Draws International Crowd to San Diego 4Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 2Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 3Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 4Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 5World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 2World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 3World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 4World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 5World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 6Guardant Health Named a 2015 Technology Pioneer by World Economic Forum 2
... , Newly Launched Donor Network Alliance Achieves Company & Industry ... June 24 Through a unique and effective collaboration of ... Network Alliance (DNA) - the industry,s first ever web-based collective ... largest egg donation resources in the country with more than ...
... Release Highlights, - Melogliptin continues to demonstrate potential to be ... incidence of, hypoglycemia and neutral effect on body ... end 2009, - IND approved by USFDA, ... Indian company to have a truly global innovative drug for the ...
... PROMOTIONAL SYSTEMS, INC. (Pink Sheets: VGPR) today announced through ... planning to construct a manufacturing facility in the State ... , , According to a recent Forbes Magazine ... abundance of biomass in Georgia,s Bioenergy Corridor ranks third ...
Cached Biology Technology:First-Ever Egg Donor Web Portal Becomes One of The Largest Resources for Aspiring Parents in the U.S. 2Glenmark's Novel Molecule for Diabetes, Melogliptin to Enter Phase III Trials 2Natural Fuels Industries Eyes 'Biomass Rich' Georgia for Production Facility 2Natural Fuels Industries Eyes 'Biomass Rich' Georgia for Production Facility 3
... the space and time dimensions of a streak ... microscope to open new horizons in biological imaging. ... excitation, the decay of a fluorescence emission can ... measured. Subtle changes in the local environment ...
... ScriptCap™ m7G Capping system ... and all of the components ... 0 on the end of ... These kits feature high efficiency ...
Extracti-Gel D Detergent Removing Gel...
... T1 Thermocycler provides high speed and excellent ... with a TGradient Thermocycler can be run ... with a silver block for 48 or ... well plates or in-situ applications are available. ...
Biology Products: