Navigation Links
Hormone acting as 'molecular glue' could boost plant immune systems
Date:10/6/2010

EAST LANSING, Mich. The discovery of a hormone acting like molecular glue could hold a key to bolstering plant immune systems and understanding how plants cope with environmental stress.

The study, which is featured in the Oct. 6 issue of Nature, reveals how the plant hormone jasmonate binds two proteins together an emerging new concept in hormone biology and protein chemistry. The study also identifies the receptor's crystal structure to provide the first molecular view of how plants ward off attacks by insects and pathogens.

In short, the work explains how a highly dynamic form of plant immunity is triggered, said Gregg Howe, biochemistry and molecular biology professor, who worked with fellow MSU professor Sheng Yang He on the study. The study is a collaboration between the MSU-Department of Energy Plant Research Laboratory and the University of Washington.

"In many respects, this receptor is novel in how it binds its target hormone to switch on gene expression," Howe said. "Jasmonate appears to act as molecular glue that sticks two proteins together, which sets off a chain of events leading to the immune response. Determining the structure of the receptor solves a big missing piece of the puzzle."

Earlier research conducted by Howe and He helped to unveil the mechanism of action of jasmonate, the last major plant hormone to have its signaling pathway decoded. When a plant is attacked, the jasmonate signal causes direct interaction between a family of JAZ repressor proteins and the F-box protein COI1, which works to eliminate JAZ proteins so the plant can mount a defense.

Reconstructing the molecular mechanism of jasmonate perception revealed a multicomponent signaling hub. Instead of working as a single protein, which is typical of most receptors, this new receptor is actually a co-receptor complex that consists of COI1, JAZ and a newly discovered third component, inositol pentakisphosphate, Howe said.'/>"/>

Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. UNH researcher helps identify key reproductive hormone in oldest vertebrate
2. Marriage and committed romance reduce stress-related hormone production
3. Cancer risk found for long-term hormone therapy
4. UBC researcher discovers ancient stress hormone in pre-historic fish
5. MSU sea lamprey research sheds light on how stress hormones evolved
6. Plant growth hormones: Antagonists cooperate
7. UM School of Medicine scientists find hormone influences sensitivity to sweetness
8. New study documents use of hormone progesterone in simple microscopic aquatic animals
9. Discovery: Yeast make plant hormone that speeds infection
10. Hormone spray improves male sensitivity
11. Hormone sensitivity of breast stem cells presents drug target
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into ... key or the answer to your secret question. What,s your ... Today, Hoyos Labs , a digital infrastructure security ... an end to the frustration that comes with usernames, passwords ... a user,s smartphone to acquire his or her biometrics to ...
(Date:12/10/2014)... 9, 2014 CIE San Diego has launched ... the connective tissue that enhances care coordination among social ... share client-level information; earned a second $1 million grant ... serving seniors aging in community and; will be recognized ... 11 th 4-6p. CIE San Diego ...
(Date:12/5/2014)... , Dec. 4, 2014 Increased ... boosted investments in new testing and inspection technologies. ... given rise to a range of innovative test ... requirements of Generation Y, which is generally more ... a result, product development strategies of test equipment ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4
... discovered that individuals with obsessive compulsive disorder (OCD) and ... brain structure. This is the first time that ... for the disorder. These new findings, reported today ... are at risk of developing OCD and lead to ...
... STORING carbon dioxide deep below the earths surface could be ... contributors to climate change. University of Leeds research shows ... could provide a safe reservoir for carbon dioxide. The study ... had been predicted - such reactions are essential if the ...
... scientists have devised a tool to help understand and ... all 70,000 nucleosomes in yeast. Nucleosomes wrap DNA before ... and regulators of a cells state. Led by ... the Banting and Best Department of Medical Research and ...
Cached Biology News:Brain pattern associated with genetic risk of obsessive compulsive disorder 2Planting carbon deep in the earth -- rather than the greenhouse 2
(Date:12/17/2014)... 2014 Ipsen Biopharmaceuticals, Inc., an ... IPSEY), today announced that Somatuline® Depot® ... was approved by the U.S. Food and Drug ... tumors (GEP-NETs) in adult patients with unresectable, well ... to improve progression-free survival (PFS). , “The approval ...
(Date:12/17/2014)... Texas (PRWEB) December 17, 2014 ... on Global Quartz Tubing industry. For an overview ... definition, classification, application, industry chain structure, industry overview, ... quartz tubing industry has witnessed rapid ... a number of acquisitions. This report mentions quartz ...
(Date:12/17/2014)... Menlo Park, CA (PRWEB) December 17, 2014 ... Inc. announces today that it has entered into ... Daniels Midland Company (ADM) to apply DNA2.0’s proprietary ... industrial enzyme engineering process. , “We are extremely ... our ProteinGPS engineering platform. This proprietary bioengineering ...
(Date:12/17/2014)... 16, 2014  Vermillion, Inc. (NASDAQ: VRML ... today announced the next step in its expanded strategy ... provider with the naming of current Chief Operating Officer, ... Officer, while current Chairman of the Board and CEO ... Chairman. These changes are effective January 1, 2015. ...
Breaking Biology Technology:Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 82020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4
... predicts the Alzheimer's disease drug market in ... by 15 percent annually for the next five ... entitled "Global Markets for Alzheimer's Disease Medications 2005," ... in an Alzheimer's drug market that generated more ...
... I just returned from attending the 2nd Annual Future ... which people from business, government and community economic development came ... to make it real. , ,The historic Society Hill district ... held includes an attractive mix of the old, the restored ...
... and even adjudicated about peer-to-peer music sharing that it would ... legitimize song sharing. Yet Mercora really is different, ... have downloaded the software since its quiet debut about nine ... the IM stands for Individual Modulation has transformed from ...
Cached Biology Technology:Alzheimer's drug market to hit $5.5 billion by 2009, study says 2The future of work is now 2The future of work is now 3The future of work is now 4Mercora gets music sharing right 2Mercora gets music sharing right 3
Mouse HAI-1 Ectodomain MAb (Clone 199732)...
... Recognizes K+ Cl- Cotransporter-1 ... no significant sequence homology ... CCC.,SPECIES REACTIVITIES: The immunogen ... in human, mouse, porcine ...
IEX-1 S/L (H-20)...
Mouse monoclonal [1.T.4] to WAVE 1 ( Abpromise for all tested applications). Antigen: His6 fusion protein corresponding to full-length rat WAVE1. Entrez Gene ID: 8936...
Biology Products: