Navigation Links
Hormonal contraceptives associated with higher risk of female sexual dysfunction
Date:5/3/2010

Women taking non-oral and oral hormonal contraceptives were at highest risk of Female Sexual Dysfunction (FSD), according to a study of female German medical students published today in The Journal of Sexual Medicine. Interestingly, women taking non-hormonal contraceptives were at lowest risk for FSD, more than women not using any contraceptive.

"Sexual problems can have a negative impact on both quality of life and emotional well-being, regardless of age," said researcher Dr. Lisa-Maria Wallwiener of the University of Heidelberg, Germany. "FSD is a very common disorder, with an estimated prevalence of about two in five women having at least one sexual dysfunction, and the most common complaint appearing to be low desire."

"The causes of FSD are multifunctional and in recent years the possible role of hormonal contraception has been discussed," said fellow researchers Drs. Christian and Markus Wallwiener, University of Tuebingen, Germany. "Women tend to be aware that sexual dysfunction is often influenced by various factors such as stress and relationships, but our study has shown it might also be influenced by exogenous hormone application."

1,086 women were included in the study (roughly 2.5% of the overall female medical student population in Germany), who completed questionnaires designed to identify problems with sexual function, as well as other lifestyle factors including desire for children, pregnancy and whether they were smokers. 87.4% had used contraceptives in the last 6 months, and 97.3% had been sexually active within the last four weeks.

To analyse the effect of contraception on sexual function, women using multiple forms of contraception or who had not been sexually active within the last four weeks were excluded, leaving 1046 participants. Of this figure, 32.4% were considered at risk for FSD: 5.8% at high risk for hypoactive sexual desire disorder, 1% for arousal disorder, 1.2% for decreased lubrication, 8.7% for orgasm disorder, 2.6% for satisfaction problems, and 1.1% for pain.

The participants were then divided into four subgroups of oral (hormonal) contraception (OC), non-oral hormonal contraception (NOHC), nonhormonal contraception (NHC), and no contraception (NC). The group at lowest risk for FSD (highest sexual function score) was NHC (31.0), followed by NC (29.5) and OC (28.3), with NOHC (27.4) at highest risk. For desire and arousal, both OC and NOHC groups were at highest risk.

The method of contraception and smoking status were significant factors for total sexual function scores, with smokers scoring higher than non-smokers. Other factors including age, prior pregnancy, desire for children, and partnership status were not significant. Women not in stable relationships (regardless of contraception use) had higher desire but lower orgasm scores.

"In future research it would be interesting to see if there is a difference between the dosage of estrogen and the various synthetic progestins used in hormonal contraceptives in terms of an impact on female sexual function," added study researcher Dr. Harald Seeger, also of University of Tuebingen, Germany. "We would also urge some caution in interpretation of our present results and would like to highlight that this type of study cannot demonstrate causality but rather association and there might exist a multitude of factors that have an impact on female sexual function."

"This is a very important research investigation", stated Dr. Irwin Goldstein, Editor-in-Chief of the Journal of Sexual Medicine. "There are hundreds of millions of women, in particular young women at the beginning of their sexual lives, who regularly use hormonal contraception for many years. The irony is that these women are provided a medication that enables freedom from reproductive worries but these same women are not provided information that there are significant adverse sexual effects that may ensue.

"Agents that interfere with the hormonal milieu of women may adversely affect their sexual lives"


'/>"/>

Contact: Jennifer Beal
medicalnews@wiley.com
44-012-437-70633
Wiley-Blackwell
Source:Eurekalert

Related biology news :

1. Breast cancer cells recycle to escape death by hormonal therapy
2. Major NSF grant boosts UNH research on hormonal genomics
3. The pill for him: Scientists find a hormonal on-and-off switch for male fertility
4. Soy germ-based supplement SE5-OH containing natural S-Equol examined for safety, hormonal influence
5. Texas A&M testing oral contraceptives for animals
6. Continuous oral contraceptives better at easing pain, bleeding
7. Oral contraceptives impair muscle gains in young women
8. Oral contraceptives impair muscle gains in young women
9. Study explains potential failure of oral contraceptives with obese women
10. Socioeconomic position associated with effectiveness of HIV drugs
11. Weight gain between first and second pregnancies associated with increased odds of male second child
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/11/2017)... , Jan. 11, 2017 Intoxalock, a leading ... the release of its patent-pending calibration device. With this ... perform calibrations, securely upload data logs and process repairs ... customer. "Fighting drunk driving through the application ... public at large, but also for the customer who ...
(Date:1/6/2017)... Jan. 6, 2017  Privately-held CalciMedica, Inc., announced ... healthy volunteers of a novel calcium release-activated calcium ... pancreatitis. Acute pancreatitis, sudden painful ... disorder, but can be very serious.  In severe cases ... where extended hospital stays, time in the ICU ...
(Date:1/6/2017)... 5, 2017  Delta ID Inc., a leader in ... for automotive at CES® 2017. Delta ID has collaborated ... demonstrate the use of iris scanning as a secure, ... driver in a car, and as a way to ... Delta ID and Gentex will demonstrate (booth ...
Breaking Biology News(10 mins):
(Date:1/21/2017)... Interpace Diagnostics Group, Inc. (NASDAQ: IDXG)("Interpace" ... useful molecular diagnostic tests and pathology services, today ... purchase agreement with three  institutional investors to purchase ... in a registered direct offering.  In a concurrent ... to the same investors warrants to purchase 855,000 ...
(Date:1/21/2017)... Jan. 20, 2017 Aratana Therapeutics, Inc. (NASDAQ: ... on the licensing, development and commercialization of innovative biopharmaceutical ... Best Company in North America ... award based on the FDA approval of three ... ENTYCE ® (capromorelin oral solution) and NOCITA ® ...
(Date:1/20/2017)... , ... January 20, 2017 , ... The two newest ... treatment options for patients. Vironika, a spin out from The Wistar Institute, and Sanguis, ... lab space at 3624 Market Street. , Vironika is developing a treatment for ...
(Date:1/20/2017)... , Jan. 20, 2017 Ginkgo ... of Gen9, a pioneer in the synthesis and ... unique expertise in assembling pathway-length synthetic DNA into ... and capacity in the construction of new organism ... industries. "Gen9 was founded to significantly ...
Breaking Biology Technology: