Navigation Links
Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death
Date:3/22/2009

QT interval by any one of the genetic variants, the alteration amounts to just a couple milliseconds, which is not a huge amount, says Arking: "But if you put all 10 genetic variants together, that bumps up the QT interval by about 20 milliseconds, which is significant."

This latest study builds on research published in 2006, when a screen of 100,000 sites in individuals of European ancestry first showed that the Nos1ap gene is associated with the QT interval; and subsequent research showing that sequence changes in Nos1ap are also a risk factor for sudden cardiac death. A third paper, published in January 2009 in PLoS one, widened the original screen to include multiethnic populations; that study confirmed that Nos1ap genetic variants alter QT interval in all populations and, in fact, have a stronger effect in women than men.

"The reason people die from this cardiovascular disorder is because we know nothing about the antecedents," Chakravarti says. "It's like a truck barreling down a slope: there's no way to stop it. The only way out is to understand the science of this in a deep, meaningful way. If we know, we can begin to intervene."


'/>"/>

Contact: Maryalice Yakutchik
myakutc1@jhmi.edu
443-287-2251
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Vaginal reconstruction not needed for most inter-sex females, Hopkins study shows
2. Worth a thousand words: Hopkins researchers paint picture of cancer-promoting culprit
3. Johns Hopkins scientists discover what drives the development of a fatal form of malaria
4. Hopkins researchers piece together gene network linked to schizophrenia
5. Johns Hopkins researchers detect sweet cacophony while listening to cellular cross-talk
6. Johns Hopkins scientists pull proteins tail to curtail cancer
7. UK scientists working to help cut ID theft
8. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
9. Comet probes reveal evidence of origin of life, scientists claim
10. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
11. Male elephants get photo IDs from scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/8/2015)... YORK , July 8, 2015 Summary ... globally, and the fourth most fatal, with a mortality ... The poor prognosis of pancreatic cancer patients has highlighted ... treatment, which is not being met by the current ... an array of products with varying molecule types and ...
(Date:7/7/2015)... June 30, 2015 ... the addition of the "Capacitive Fingerprint Sensors ... To this date, fingerprint sensing technology is ... fingerprint sensors are well developed. This patent landscape ... The domain of capacitive fingerprint sensors ...
(Date:7/2/2015)... 25, 2015 Research and ... "Next Generation Biometrics Market by Application, Technology, Function ... to their offering. The next generation biometrics ... at a CAGR of 17.9% between 2015 and 2020 ... for the market. Safran SA ( ...
Breaking Biology News(10 mins):Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3
... habitats where light may be a limiting factor. In ... (lacking chlorophyll), as well as green, orchids depend on ... in order to grow. However, orchids are found in ... photosynthetic capabilities. For those orchids that are fully ...
... Clearwater Beach, FL. Research to be presented at ... Study of Ingestive Behavior (SSIB), the foremost society for ... suggests that people can become dependent on highly palatable ... similar to the behaviors we observe in drug addicts ...
... Vegetation in towns and cities can make a significant ... even more carbon if local authorities and gardeners planted and ... British Ecological Society,s Journal of Applied Ecology , is ... vegetation within an urban area of Europe. Using satellite ...
Cached Biology News:Orchids and fungi: An unexpected case of symbiosis 2Orchids and fungi: An unexpected case of symbiosis 3Orchids and fungi: An unexpected case of symbiosis 4Evidence for 'food addiction' in humans 2Plants in cities are an underestimated carbon store 2
(Date:7/29/2015)... , July 29, 2015 /PRNewswire/ - RepliCel Life ... stage regenerative medicine company, is pleased to announce that ... injector (RCI-02) have been locked.  Prototypes for industrial ... prepare for an application for CE mark clearance ... in 2016. (Photo: ...
(Date:7/29/2015)... San Bruno, CA. (PRWEB) , ... July 29, ... ... partnership agreement with PRC Clinical, a Silicon Valley-based CRO specializing in ... FDA advisory services, and patient recruitment services. The core expertise of PRC Clinical ...
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... ... Industries’ (BI) advanced cell culture products, announces the availability of BI’s line of ... by Biological Industries, these stem cell differentiation media offer a complete system for ...
(Date:7/28/2015)... A n ... rapidly developing and commercialising innovative medicines to transform patient quality ... Highly experienced management team; blue chip ... Mereo BioPharma Group Ltd ("Mereo"), a recently-formed speciality biopharmaceutical company, ... £76.5m), gross, from blue chip institutional investors and simultaneously acquired ...
Breaking Biology Technology:RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 2RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 3RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 4RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 5CSSi LifeSciences And PRC Clinical Join Forces To Offer Extended Clinical Trial Services 2CSSi LifeSciences And PRC Clinical Join Forces To Offer Extended Clinical Trial Services 3Rainbow Scientific, Inc. Announces Availability of Human Mesenchymal Stem Cell Differentiation Media 2Rainbow Scientific, Inc. Announces Availability of Human Mesenchymal Stem Cell Differentiation Media 3Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 2Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 3Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 4Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 5Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 6Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 7Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 8Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 9Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 10Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 11
... , MOUNTAIN VIEW, ... Partnership Company, honored healthcare companies for demonstrating leadership and ... Healthcare Innovation Awards Banquet held in San Antonio, Texas. ... Innovation Awards are given to companies that have made ...
... , CARY, N.C., Nov. 23 Cornerstone Therapeutics Inc. ... acquiring, developing and commercializing significant products primarily for the respiratory ... and Chief Executive Officer, will be presenting a corporate overview ... 3:30 PM ET on Wednesday, December 2, 2009 at The ...
... an opportunity to take the lead in two small ... working together with the IDICHUS Foundation, have studied the ... is that Spain,s food and plant sectors have more ... applied to food and plants has been overlooked by ...
Cached Biology Technology:Excellence in Healthcare Innovation Recognized by Frost & Sullivan 2Excellence in Healthcare Innovation Recognized by Frost & Sullivan 3Cornerstone Therapeutics to Present at the 21st Annual Piper Jaffray Health Care Conference 2Cornerstone Therapeutics to Present at the 21st Annual Piper Jaffray Health Care Conference 3Spanish biotechnology should focus on food and plant sectors to be more competitive 2
Human/Mouse G9a/EHMT2 MAb (Clone A8620A) Keywords: Eu-HMTase2...
Mouse GDF-8 Propeptide Affinity Purified Polyclonal Ab...
SRY (sex determining region Y)-box 10...
Normal human serum, single donor...
Biology Products: