Navigation Links
Hopes for reversing age-associated effects in MS patients
Date:1/6/2012

New research highlights the possibility of reversing ageing in the central nervous system for multiple sclerosis (MS) patients. The study is published today, 06 January, in the journal Cell Stem Cell.

As we get older, our bodies' ability to regenerate decreases. This is not only true for our skin (which is evident in the wrinkles that develop as we age) but also true for other tissues in the body, including the regenerative processes in the brain. For diseases which often span several decades and are affected by regenerative processes, such as multiple sclerosis, this can have massive implications.

In multiple sclerosis, the insulating layers that protect nerve fibres in the brain, known as myelin sheaths, become damaged. The loss of myelin in the brain prevents nerve fibres from sending signals properly and will eventually lead to the loss of the nerve fibre itself. However, early in the disease, a regenerative process, or remyelination, occurs and the myelin sheaths are restored. Unfortunately, as people with MS age, remyelination decreases significantly, resulting in more nerve fibres being permanently lost.

However, a new study in mice shows that the age-associated decline in the regeneration of the nerve's myelin sheath, or remyelination, is reversible. The proof of principle study demonstrates that when old mice are exposed to the inflammatory cells (called monocytes) from young mice, the ageing remyelination process can be reversed.

Professor Robin Franklin, Director of the MS Society's Cambridge Centre for Myelin Repair at the University of Cambridge, said: "What we have shown in our study, carried out in collaboration with Dr Amy Wagers and colleagues at Harvard University, is that the age-associated decline in remyelination is reversible. We found that remyelination in old adult mice can be made to work as efficiently as it does in young adult mice.

"For individuals with MS, this means
'/>"/>

Contact: Genevieve Maul
gm349@admin.cam.ac.uk
01-223-332-300
University of Cambridge
Source:Eurekalert

Page: 1 2

Related biology news :

1. Purdue startup hopes to change the way we test cancer drugs
2. Team hopes to cut years off development time of new antibiotics
3. Reversing aging
4. New breathing therapy reduces panic and anxiety by reversing hyperventilation
5. Study reveals new possibility of reversing damage caused by MS
6. Preventing or reversing inflammation after heart attack, stroke may require 2-pronged approach
7. Reversing ecology reveals ancient environments
8. Scientists identify age-associated defects in schizophrenia
9. Wayne State study finds soybean compounds enhances effects of cancer radiotherapy
10. Researchers assess effects of a world awash in nitrogen
11. Submarine springs offer preview of ocean acidification effects on coral reefs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... , June 30, 2015 ... announced the addition of the "Capacitive Fingerprint ... To this date, fingerprint sensing technology ... and fingerprint sensors are well developed. This patent ... technology. The domain of capacitive fingerprint ...
(Date:7/2/2015)... , June 25, 2015 ... of the "Next Generation Biometrics Market by Application, ... report to their offering. The next ... by 2020, at a CAGR of 17.9% between 2015 ... leading application for the market. Safran SA ...
(Date:6/29/2015)... , June 24, 2015 ... of the "Latin America Biomedical Sensors Market - ... offering. The Latin America Biomedical Sensors market ... CAGR of 2.04% over the period 2014-2020 ... adaptable to the genetic formulation of each individual. These ...
Breaking Biology News(10 mins):Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3Latin America Biomedical Sensors Market Report 2015-2020 2
... When we absorb new information, the human brain reshapes itself ... new knowledge kept, and how does that capacity to adapt ... senile dementia later in our lives? Dr. Yaniv Assaf ... new way to track the effect of memory on brain ...
... Arizona researchers have added another piece to the ... to treat patients in cardiac arrest, "passive ventilation" significantly ... ventilation." The study, published in an online edition ... patients who had suffered a cardiac arrest outside a ...
... Jerusalem have succeeded for the first time in devising ... mechanism that enables networks of neurons to efficiently decode ... lead to the upgrading of computer algorithms for faster ... the development of innovative treatments for auditory problems among ...
Cached Biology News:A window into the brain 2Cardiac arrest resuscitation: Passive oxygen flow better than assisted ventilation 2Hebrew U. researchers shed light on the brain mechanism responsible for processing of speech 2
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... ... has appointed Francois Vieillard as Sales & Marketing Director. , With more ... Vieillard will be responsible for reinforcing Tronics’ business development activities worldwide. He brings ...
(Date:7/30/2015)... 2015 According to a new ... Modeling, PB/PK, PKPD, Trial Design, Toxicity Prediction, In-house, Contract ... Trial), by End Users - Global Forecast to 2020", ... reach USD 2,107.99 million by 2020 from USD 1,034.93 ... Browse more than 75 ...
(Date:7/30/2015)... July 30, 2015   Aratana Therapeutics, Inc ... company focused on the licensing, development and commercialization ... announced that its strategic partner VetStem Biopharma, Inc. ... study of AT-016, an adipose-derived allogeneic stem cell ... of osteoarthritis pain in dogs. The ...
(Date:7/30/2015)... 30, 2015  With over 60,000 customers across the globe, ISN improves the efficiency ... organizations with more than 60,000 safe and reliable contractors in over 80 countries. ... ... Over 60,000 Worldwide ... Headquartered in Dallas, TX , ISN ...
Breaking Biology Technology:Tronics appoints Francois Vieillard as Sales and Marketing Director 2Biosimulation Market Worth 2,107.99 Million USD by 2020 2Biosimulation Market Worth 2,107.99 Million USD by 2020 3Biosimulation Market Worth 2,107.99 Million USD by 2020 4Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 2Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 3Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 4Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 5ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3
... (PDL) (Nasdaq: PDLI ) today announced that it ... $0.50 per share to all stockholders owning shares of PDL ... As previously announced, the conversion rate for the Company,s ... to 140.571 shares of common stock per $1,000 principal amount ...
... 1 Maven Biotechnologies today announced that the company ... for Allergy and Infectious Disease (NIAID), part of the ... imaging technology for label-free protein microarrays and cell-based ... through the federal stimulus package initiative for Biomedical Research, ...
... The Culex quinquefasciatus mosquito poses a significant ... elephantiasis-causing worms and encephalitis-inducing viruses. An international team of ... the SIB Swiss Institute of Bioinformatics sequenced its genome ... published in today,s issue of Science, describe results from ...
Cached Biology Technology:Maven Biotechnologies Receives $1.96 Million From the National Institutes of Health (NIH) to Develop Their LFIRE™ Label-Free Detection Technology for Proteomics 2Major disease-vector mosquito reveals the secrets of its immune system 2
... ovens are designed to create the ideal environment ... (ambient to 99.9C) , Variable speed control ... samples, whether it be for washing or hybridizing ... current temperature inside the chamber, ,is situated above ...
... magnetic particle based purification systems provide high ... any sample. They offer increased throughput and ... systems- KingFisher, KingFisher mL and KingFisher 96, ... l. Each system consists of an instrument, ...
... is the latest edition to the famous ... an extra large diameter exhaust port for ... panel allows precise setting and control of ... handling large quantities and samples , ...
... Thermo Savant SpeedVac Concentrators set the standard ... SC110A SpeedVac uses a combination of centrifugal force, ... a single run., SC110A comes equipped with:, , ... chemical compatibility , ...
Biology Products: