Navigation Links
Hope for a rabies eradication strategy in Africa
Date:1/21/2009

Most of the rabies virus circulating in dogs in western and central Africa comes from a common ancestor introduced to the continent around 200 years ago, probably by European colonialists. In the current issue of Journal of General Virology a team of scientists from Africa, USA and France report that within this common ancestry there are distinct subspecies at country level and that there is only limited movement of virus between localities. These factors mean that, if neighbouring countries collaborate, a progressive strategy to eliminate rabies from this area of sub-Saharan Africa is possible.

Rabies causes over 24,000 deaths a year in Africa, mostly in poor rural communities and of children. Rabies prevention and treatment are costly and the necessary resources often scarce or inadequate. Controlling rabies in dogs, the main agents of rabies spread, is therefore an important part of any rabies eradication programme.

The team analysed 182 samples of dog rabies virus from 27 African countries taken over a time period of 29 years. Their analyses showed that the samples were of two types, which they call "Africa 1" and "Africa 2" with different geographical distribution and history, indicating a clear distinction between rabies viruses circulating in North Africa and those circulating in West/Central Africa. It appeared that "Africa 2" was introduced into the eastern part of West/Central Africa probably in Chad around 200 years ago and from there spread over the whole region, moving westwards and southwards, over a 100-year period. This spread follows the pattern of French colonial expansion in Africa. Distinct subpopulations of the virus exist in the different African countries and there is very little evidence that there is much movement of the virus among localities.

Dr Herv Bourhy, from the Institut Pasteur in Paris who led the research said:

"Some scientists have suggested that rabies outbreaks in Africa might be caused by "superspreader" dogs, transmitting the disease over large distances. Our findings show that this is extremely unlikely as there is strong geographical clustering of the dog rabies subspecies and the time-scale for diffusion of the virus is measured in decades. Similarly, people transporting dogs, some of them eventually becoming infectious or in incubation, over this vast region does not seem to have had much, if any, impact on the spread of disease".

Chiraz Talbi, the researcher who carried out the analysis, added: "Rabies kills a patient, most often a child, every 20 minutes in Africa. By identifying the species of the virus that is the most prevalent and demonstrating how it spreads through the region, we have shown that, with collaboration, it should be possible for African countries to eliminate rabies by controlling dog rabies"


'/>"/>

Contact: Dianne Stilwell
d.stilwell@sgm.ac.uk
44-020-897-76510
Society for General Microbiology
Source:Eurekalert

Related biology news :

1. Mitochondria could be a target for therapeutic strategy for Alzheimers disease patients
2. GUMC researchers hone in on new strategy to treat common infection
3. Effects of anthropogenic sound on marine mammals -- a research strategy
4. Scientists uncover Ebola cell-invasion strategy
5. New study raises concerns about proposed mitigation strategy for marine bycatch
6. Novel therapeutic strategy for colon cancer treatment
7. Insects evolved radically different strategy to smell
8. A built-in strategy for transgene containment
9. A screening strategy using zebrafish targets genes that protect against hearing loss
10. ETH Zurich competence center ESC introduces energy strategy
11. Strategy for nanotechnology-related environmental, health and safety research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/6/2017)... , March 6, 2017 Mintigo ... technology, today announced Predictive Sales Coach TM , ... actionable sales intelligence into Salesforce. This unique AI ... their sales organizations with deep knowledge of their ... for intelligent engagement. Predictive Sales Coach extends Mintigo,s ...
(Date:3/2/2017)... 2017 Australian stem cell and regenerative medicine ... signed an agreement with the Monash Lung Biology Network, ... Institute and Department of Pharmacology at Monash University, ... study to support the use of Cymerus™ mesenchymal stem ... Asthma is a chronic, long term lung condition ...
(Date:2/28/2017)... , Spanien, 27. Februar 2017  EyeLock LLC, ein ... wird seine erstklassige biometrische Lösung zur Iris-Erkennung ... mit X16 LTE auf dem Mobile World ... am Qualcomm-Stand in Halle 3, Stand 3E10, ... die Sicherheitsplattform Qualcomm Haven™ – eine Kombination ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... Research and Markets has announced the addition of ... offering. ... The Global Market for Bioproducts Should Reach $714.6 Billion ... of 8.9%, This research report quantifies the ... product segments: bio-derived chemicals, biofuels, pharmaceuticals (biodrugs and herbal/botanicals), biocomposite ...
(Date:3/23/2017)... 23, 2017  SeraCare Life Sciences, Inc., a ... vitro diagnostics manufacturers and clinical laboratories, is ... multiplexed Inherited Cancer reference material ... next-generation sequencing (NGS). The Seraseq™ Inherited Cancer DNA ... from industry experts to validate the ability ...
(Date:3/23/2017)... March 23, 2017  BioPharmX Corporation (NYSE MKT: ... the dermatology market, today reported financial results for ... and will provide an update on the company,s ... "We are pleased to report that ... BioPharmX," said President Anja Krammer. "We achieved key ...
(Date:3/23/2017)... , March 23, 2017 Kineta, Inc., ... of novel therapies in immuno-oncology, today announced the ... small molecule compounds that activate interferon response factor ... and demonstrate immune-mediated tumor regression in a murine ... study who demonstrated complete tumor regression to initial ...
Breaking Biology Technology: