Navigation Links
Hong Kong University leads the genomics research of scarlet fever pathogen
Date:6/22/2011

Scarlet fever has revealed unusual high infect rate in Hong Kong this year. So far, 466 children were infected and 2 of them dead. Scarlet fever is caused by Streptococcus pyogenes, a gram-positive pathogen that can be transmitted via skin wound and airborne droplet.

Under the guidance of Hong Kong Center for Disease Control (HK CDC), Hong Kong University (HKU) and their partners today released the draft genome sequence of the S. pyogenes strain that was isolated from a scarlet fever patient (Sequence has been uploaded to NCBI AN: SRA038808 and is available for immediate download at ftp://ftp.genomics.org.cn/pub/S.pyogenes/). Current analysis results indicate that this strain belongs to M12 serotype, which was widely distributed in Europe, North America, South America, and Asia. No significant virulence characters were observed on this type of S. pyogenes strain. There is 95.2% genomic region of this strain can be aligned to two previously fully sequenced M12 strains and 4.8% (around 90 kbp) is specific to this strain. It is possible that the specific sequences in this strain may result in the increase of virulence and improved spread ability.

HKU and their collaborators are continuing on the intense research of this pathogen. The whole genome fine map of this S. pyogenes will be released within a week. The team will further explore the source of the specific virulent-related sequences and possible pathogenicity mechanism by comparing the previous S. pyogenes isolates in Hong Kong and the current sequenced strain. The research results will provide scientific evidences to facilitate the control of the infectious rate as well to develop effective measures to prevent the spread of scarlet fever.

It is reported that the draft genome sequence and preliminary analysis results were accomplished by HKU and BGI-HongKong. Earlier this month, BGI-Shenzhen and University Medical Centre Hamburg-Eppendorf worked together to firstly develop the complete whole genome sequence of the Germany Escherichia coli outbreak strain.


'/>"/>

Contact: Bicheng Yang
yangbicheng@genomics.cn
86-150-138-65386
Beijing Genomics Institute
Source:Eurekalert

Related biology news :

1. Not-so-sweet potato from Clemson University, USDA resists pests, disease
2. University of Texas at Austin professor receives Donald L. Katz Award
3. University of Iowa researchers identify caffeine-consuming bacterium
4. University of Arizona awarded $2.95 million to study monsoon ecology
5. Syracuse University scientists discover new hitch to link nerve cell motors to their cargo
6. Tel Aviv University confers its highest honor on 8 distinguished individuals
7. Research teams at Hebrew University, University of Kentucky win Israel-US science award
8. Tel Aviv Universitys Sackler Prizes awarded to 2 North American chemists
9. University pond reveals hidden history of fungi
10. Clemson University institute to study vertical farming feasibility in Charleston, S.C.
11. University of Tennessee scientist: Flowers rapid growth rate can be traced back 65 million years
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... , June 9, 2016  Perkotek an innovation leader in attendance control systems ... seamlessly log work hours, for employers to make sure the right employees are actually ... http://photos.prnewswire.com/prnh/20160609/377486LOGO ... ... ...
(Date:6/3/2016)... LONDON , June 3, 2016 /PRNewswire/ ... Transport Management) von Nepal ... ,Angebot und Lieferung hochsicherer geprägter Kennzeichen, einschließlich ... weltweit führend in der Produktion und Implementierung ... an der Ausschreibung im Januar teilgenommen, aber ...
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced ... this eBook by providing practical tips, tools, and strategies for clinical researchers. , ...
(Date:6/23/2016)... , June 23, 2016 /PRNewswire/ - FACIT ... Ontario biotechnology company, Propellon Therapeutics ... development and commercialization of a portfolio of first-in-class ... Epigenetic targets such as WDR5 represent an exciting ... significantly in precision medicine for cancer patients. Substantial ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm Sciences, Inc. is pleased ... received AOAC Research Institute approval 061601. , “This is another AOAC-RI approval of ... Salter, Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods perform ...
Breaking Biology Technology: