Navigation Links
Honey bee gene targeting offers system to understand food-related behavior
Date:7/25/2013

On July 25th JoVE, the Journal of Visualized Experiments will publish a new technique that will help scientists better understand the genes that govern food-related behavior in honey bees. The impact of this study could take scientists one-step closer toward understanding and perhaps changing undesirable food-related behavior in humans via gene control.

"Our technique has already helped to unravel [the] complex gene networks behind biological processes and behavior, such as gustatory perception," said Dr. Ying Wang of Arizona State University. She and a team of scientists are behind the experiment, titled RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees. "Honey bees are much less complex than mammals and humans, but [we] share many major genes," said Wang, "therefore, honey bees have become an emerging system for us to understand food related behavior in humans."

In Wang's previous study, she found that carbohydrate metabolism and insulin pathway genes were involved in honey bee gustatory perception. Her new article introduces two strategies for targeting and simultaneously down-regulating multiple genes in honey bees via RNA interference. This allows for further research in examining the role of insulin metabolism in gustatory perception. The team believes it will be important to understanding how insulin pathways play a role in food-related behavior.

Wang's multiple gene knockdown method is a first in entomology, and it overcomes the many shortfalls associated with typical single-gene targeting methods. A common problem associated with single gene suppression is that it is not sufficient to show the interrelationship of a gene network.

In the article published today, Wang's team has also provided a technique to measure the resulting changes in honey bee behavior, and this has led them to interesting observations. "Gustatory perception is a behavioral predictor for honey bee social behavior," said Wang. A honey bee's sensitivity to sugar predicts the food-choices and timing of foraging.

Wang's experiment opens the door for researchers to build upon her lab's techniques. "We believe our double knockdown approach will be more recognized and shared in the field when it is published in the video journal JoVE," said Wang.

With any luck, the impact will result in more than just high-tech pest control. It could instead provide insight into human insulin pathways, potentially giving us an opportunity to learn how to control human dietary behavior.


'/>"/>

Contact: Rachel Greene
rachel.greene@jove.com
617-250-8451
The Journal of Visualized Experiments
Source:Eurekalert

Related biology news :

1. Insecticide causes changes in honeybee genes, research finds
2. Wild pollinators increase crop fruit set regardless of honey bees
3. Researchers identify new components of the epigenetic code for honey bee development
4. Honeybees harbor antibiotic-resistance genes
5. Highly contagious honey bee virus transmitted by mites
6. Commonly used pesticide turns honey bees into picky eaters
7. Selenium impacts honey bee behavior and survival
8. Can behavior be controlled by genes? The case of honeybee work assignments
9. U of M researchers develop model for better testing, targeting of MPNST
10. Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect
11. Signalling pathways meeting targeting the HER/EGFR family: Focus on breast, lung and colorectal cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... , Mar 24, 2017 Research and ... Access System Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 15.1% over the next ... This industry report analyzes the market estimates and forecasts for all ...
(Date:3/22/2017)... 21, 2017   Neurotechnology , a provider ... today announced the release of the SentiVeillance ... improved facial recognition using up to 10 surveillance, ... computer. The new version uses deep neural-network-based facial ... it utilizes a Graphing Processing Unit (GPU) for ...
(Date:3/20/2017)... 20, 2017 At this year,s CeBIT Chancellor Dr. ... manufacturer DERMALOG. The Chancellor came to the DERMALOG stand together with the ... year,s CeBIT partner country. At the largest German biometrics company the two ... face and iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... 2017 , ... RMC Pharmaceutical Solutions, Inc. announces the opening ... manage the new site. , Tim has 25 years of pharmaceutical experience, including ... as the Director of Manufacturing and Supplier Quality Assessment. This group is ...
(Date:6/22/2017)... ... June 22, 2017 , ... ... to clients throughout the biopharma and life sciences industries, continue to be in ... seeing. Tunnell’s Kip Wolf will be speaking on “The State of Information Governance ...
(Date:6/20/2017)... ... June 20, 2017 , ... Biologist Dawn Maslar MS has found ... latest book, Men Chase, Women Choose: The Neuroscience of Meeting, Dating, Losing Your Mind, ... effect on men. ”The logical next step, in my estimation, was to scientifically track ...
(Date:6/20/2017)... Francisco, CA (PRWEB) , ... June 20, 2017 ... ... patented technology for discovery of antibody therapeutics from millions-diverse immune repertoires, announces launch ... Conference in San Diego, California. Dave Johnson, PhD, CEO of GigaGen, will present ...
Breaking Biology Technology: