Navigation Links
Hold your breath: Air pollution plays role in cardiac, metabolic diseases
Date:3/7/2011

EAST LANSING, Mich. To explore one of the most critical health/environment intersections how the very air we breathe can cause heart disease and diabetes and contribute to the problems of obesity Michigan State University has been named a Clean Air Research Center by the Environmental Protection Agency.

A five-year, $8 million grant led by MSU's Jack Harkema, a University Distinguished Professor of pathobiology and diagnostic investigation in the College of Veterinary Medicine will fund three major research projects with the creation of the Great Lakes Air Center for Integrative Environmental Research. The research team will study the exact role air pollutants, most notably fine particles and ozone, have on cardiometabolic syndrome, a collection of interrelated risk factors leading to cardiovascular and metabolic diseases that affect about one third of adult Americans.

Signs of cardiometabolic syndrome include high blood pressure and sugar levels, abnormal triglycerides and cholesterol as well as obesity; all warning signs for the development of chronic diseases such as diabetes and atherosclerosis, Harkema said.

"In tandem, the cardiometabolic syndrome and air pollution threaten human health worldwide," he said. "We propose that not only are individuals with pre-existing abnormalities at greater risk for the health effects of air pollution exposure but that air pollution itself may promote the development of cardiometabolic syndrome."

MSU was one of four Clean Air Research Centers named by the EPA; Harvard University, the University of Washington in Seattle and Emory University/Georgia Institute of Technology in Atlanta were the other recipients. The $32 million federal effort aims to study a range of exposures to air pollution sources and their health effects across different life stages, among susceptible and vulnerable populations, and across communities where exposures may be of greater health risk.

"Air pollution in the Great Lakes region is complex due to a large diversity of multipollutant 'airsheds' (the atmospheric equivalent of watersheds)," said Harkema, whose research team includes investigators from MSU, the University of Michigan and Ohio State University. "This complexity is due to a large assortment of emission sources, including heavy industry, dense motor vehicle traffic and high concentrations of coal-fired power plants.

"The health effects of these multipollutant airsheds are complex and understudied."

The newly established Clean Air Research Center at MSU will specifically:

  • Explore how air pollution, specifically fine particulate matter and ozone, causes adverse cardiovascular effects (such as increased blood pressure) and other facets of the cardiometabolic syndrome (such as insulin resistance). Led by Harkema, the project will explore how exposure to multipollutant atmospheres in the Great Lakes may contribute to cardiovascular and metabolic disorders in laboratory rodents that mimic susceptible individuals.

  • Investigate whether short-term exposure to air pollution in humans instigate insulin resistance and elevate blood pressure. These studies will be led by Robert Brook at the University of Michigan.

  • Determine the long-term impacts of chronic exposure to air pollution and fine particulate matter. Led by Sanjay Rajagopalan from Ohio State University, the project will also use rodent models to study the correlation between air pollution and diet and genetics.

In addition to the three main projects, researchers at the new center will collect and characterize air pollution data for use by all the investigators

"Results from this important environmental health research will provide much needed information to protect human health and to safeguard the natural environment," said Paul Anastas, EPA's assistant administrator in the Office of Research and Development.


'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert  

Related biology news :

1. Protecting ecosystems, pollution remediation goals of research at UH
2. Pollution with antibiotics leads to resistant bacteria
3. Pollution tax rebates little help for low-income workers
4. University of Miami scientists find new way to estimate global rainfall and track ocean pollution
5. Morning-after spike in ozone air pollution from Super Bowl XLV?
6. Findings on pollution damage to human airways could yield new therapies
7. Dodds contributes to new national study on nitrogen water pollution
8. Virginia Tech engineer identifies new concerns for antibiotic resistance, pollution
9. Plants play larger role than thought in cleaning up air pollution
10. Sediment pollution should be included in water quality assessment
11. National study finds strong link between diabetes and air pollution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hold your breath: Air pollution plays role in cardiac, metabolic diseases
(Date:5/16/2016)... , May 16, 2016   EyeLock LLC , ... announced the opening of an IoT Center of Excellence ... and expand the development of embedded iris biometric applications. ... level of convenience and security with unmatched biometric accuracy, ... identity aside from DNA. EyeLock,s platform uses video technology ...
(Date:4/28/2016)... India , April 28, 2016 ... Infosys (NYSE: INFY ), and Samsung SDS, a ... that will provide end customers with a more secure, ... services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... services, but it also plays a fundamental part in enabling ...
(Date:4/19/2016)... UAE, April 20, 2016 The ... as a compact web-based "all-in-one" system solution for all ... fingerprint reader or the door interface with integration authorization ... access control systems. The minimal dimensions of the access ... into the building installations offer considerable freedom of design ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... -- The Prostate Cancer Foundation (PCF) is pleased to announce 24 new ... prostate cancer. Members of the Class of 2016 were selected from a pool ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... STACS DNA ... Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as a ... STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further ...
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
Breaking Biology Technology: