Navigation Links
Hold the medicinal lettuce
Date:6/26/2013

into the bloodstream, get into tissues, and regulate genes in those tissues."

Witwer teamed up with colleagues to check the results with a similar experiment of their own. They bought soy-based smoothies at a grocery store and tested their microRNA content, then fed the smoothies to macaques and took samples of the animals' blood.

Knowing that the concentrations of any plant microRNAs in the blood would be too low to measure directly, they used a common technique called polymerase chain reaction (PCR) to bring up the concentration of the genetic material. PCR is designed so that only certain fragments of genetic material in a sample the ones researchers choose to target will be copied. Zhang's studies had also used PCR to look for plant microRNAs.

Just as Zhang had, the Johns Hopkins team found what appeared to be the targeted plant microRNAs in the macaques' blood. But when they ran the experiment several times, they got highly variable results: Sometimes the microRNAs were present in low concentrations, and sometimes not at all. In addition, the samples from before the macaques drank the smoothies were just as likely to have the microRNAs as were the post-smoothie samples a result that just didn't make sense if the source of the microRNAs was the plant material in the drinks.

To Witwer, the results indicated that what he was seeing was not the targeted plant microRNAs, but fragments of the macaques' own genetic material that were similar enough to the targeted segments that the PCR copied them at low levels.

To test this, the team used a new technique in which PCR takes place in tiny aerosolized droplets rather than in a test tube. The advantage, Witwer says, is that by effectively running tens or hundreds of thousands of reactions at the same time, researchers can see whether the outcomes of those reactions are consistent in other words, whether the results are meaningful or just a fluke. In this case, the results were all over the pla
'/>"/>

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Medicinal toothbrush tree yields antibiotic to treat TB in new way
2. Substances from African medicinal plants could help stop tumor growth
3. Gene discovery may yield lettuce that will sprout in hot weather
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2015)... 11, 2015 According ... Control Market by Product (Cards and Readers, Biometrics, Controllers, ... Government, Industrial, Healthcare, Education) and By Geography - Global Forecast and ... the Access Control Market is expected to ... a CAGR of 10.6% between 2014 and ...
(Date:2/5/2015)... TRIANGLE PARK, N.C. , Feb. 5, 2015 /PRNewswire/ ... a specialist logistics company and has launched a new ... only Clinical Logistics Organization (CLO).  The new campaign focuses ... emphasis on patient, protocol and shipments. The ... First , aligns Marken,s priorities with its client,s ...
(Date:2/5/2015)... -- New Market Research Reports Title Global ... 2020 has Been Added to GrandViewReseach.com Report Database ... reach USD 5.10 billion by 2020, according to a ... help identify the site of tissue damage in case ... in medical imaging applications. They have been extensively used ...
Breaking Biology News(10 mins):Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken Launches New Patient-Centric Campaign 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 3
... The malaria parasite has been studied for decades, but ... humans to cause disease. In a groundbreaking study published ... an international research team has for the first time ... or off during actual infection in humans, not in ...
... the past 17 years for extracting oil is now at ... in Canada. Duvernay Petroleum is to use the ... of Bath at its site at Peace River in Alberta, ... viscous, like syrup, or even solid in its natural state ...
... HAYWARD, Calif., Nov. 27 Singulex Inc. today ... Research to develop,immunoassays on the company,s Erenna(TM) system. ... part of its Erenna Technology Access Program,(ETAP) and ... to accurately,and precisely measure specific biomarkers in human ...
Cached Biology News:Study of malaria parasite in patient blood finds distinct physiological states 2Study of malaria parasite in patient blood finds distinct physiological states 3Study of malaria parasite in patient blood finds distinct physiological states 4Massive Canadian oilfield could be exploited using new UK system 2Massive Canadian oilfield could be exploited using new UK system 3Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design 2
(Date:3/3/2015)... 2015 Research and Markets ( ... PharmaBiotech,s new report "Personalized Medicine - Scientific ... , The aim of personalized medicine ... drug to the right patient and, in some ... a patient according to his/her genotype. This report ...
(Date:3/3/2015)... , Mar. 03, 2015 Research and ... the addition of Jain PharmaBiotech,s new report ... to their offering. , Gene ... vectors, nonviral vectors and cell therapy with genetically ... of drug delivery and various routes of administration ...
(Date:3/3/2015)... PHILADELPHIA , March 3, 2015 ... agencies with tools for implementing competency-based training to comply ... DirectCourse is offering a new crosswalk ... Services (HCBS) implement competency-based training for direct service workers ... Medicare & Medicaid Services (CMS) regulations. CMS ...
(Date:3/3/2015)... 2015  Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer ... focus on protecting the microbiome, announced today that Jeffrey ... the 27th Annual ROTH Conference being held on March 8-11, ... in Dana Point, CA. Mr. Riley ... 1:00 p.m. (Pacific Time). A live webcast of ...
Breaking Biology Technology:Global Personalized Medicine Market Report 2015 - Scientific and Commercial Aspects 2014-2024 2Global Personalized Medicine Market Report 2015 - Scientific and Commercial Aspects 2014-2024 3Gene Therapy Market Report 2014-2024 - Technologies, Markets and Companies 2Gene Therapy Market Report 2014-2024 - Technologies, Markets and Companies 3Elsevier's DirectCourse Can Help States Meet and Exceed New CMS Requirements for Home and Community-Based Services 2Elsevier's DirectCourse Can Help States Meet and Exceed New CMS Requirements for Home and Community-Based Services 3Synthetic Biologics to Present at the 27th Annual ROTH Conference 2
... Chimerix, Inc., a pharmaceutical company developing orally-available ... Advanced Research and Development Authority (BARDA) of the United ... will resolve the Government Accountability Office (GAO) review of ... Inc. for the development and delivery of a smallpox ...
... is building its reputation as a bioscience center with ... Healthcare of Atlanta, two Metro Atlanta Chamber (MAC) board ... "Atlanta has a thriving bioscience community, and this pediatric ... will benefit patients not just in Georgia, but throughout ...
... With a 150 year expertise in the genetic ... a globally focused outlook, New Zealand,s biotech industry is ... and products. Led by industry organization NZBIO and New ... companies are showcasing their capabilities in human health care, ...
Cached Biology Technology:Chimerix and BARDA Reach Agreement Ending GAO Review of Smallpox Antiviral Contract 2Chimerix and BARDA Reach Agreement Ending GAO Review of Smallpox Antiviral Contract 3Chimerix and BARDA Reach Agreement Ending GAO Review of Smallpox Antiviral Contract 4MAC Members Grow Atlanta's Bioscience Reputation 2MAC Members Grow Atlanta's Bioscience Reputation 3New Zealand Brings Its Global "Game Plan" to the 2011 BIO International Convention 2
... structurally and functionally related BMPs, which are ... originally identified as protein regulators of cartilage ... in embryogenesis and morphogenesis of various tissues ... chemotaxis and apoptosis of various cell types, ...
RABBIT ANTI HUMAN TRRAP (CT) Immunogen: Recombinant C-terminal kinase-related domain of human TRRAP....
RABBIT ANTI HUMAN CHYMOTRYPSIN...
MSE ANTI CAN. CD3:FITC/RAT ANTI CD4:RPE...
Biology Products: