Navigation Links
Highlights of the Biophysical Society 56th Annual Meeting
Date:2/6/2012

disarmed protein could still kill. The finding may one day help scientists searching for new, more targeted, ways to kill antibiotic-resistant microbes.

Presentation 3217-Pos, "Targeted killing of Escherichia coli by an unfolded protein," is at 10:30 a.m. on Wednesday, Feb. 29.

Taking Back the Brain: New targets of Alzheimer's disease treatment: A promising novel target for potentially treating Alzheimer's disease has been identified in mouse experiments by a team at the University of California-Davis. The team's focus is on controlling cells in the brain known to be major inflammatory agents. These cells, called microglia, are activated by toxic beta amyloid proteins that accumulate as plaques in the brain and disrupt neuronal function, and they are major players in the initiation and progression of Alzheimer's disease. To turn off the microglia, and therefore stop their neurotoxic effects, the UC Davis team blocked the flow of potassium ions through a voltage-gated potassium channel on the microglia membrane. Results showed that the blocker inhibited plaque-induced microglia activation and the toxicity associated with it, but that it did not interfere with the useful "housecleaning" tasks that microglia perform. "Our observations raise the exciting possibility that potassium channel blockers might preferentially inhibit the action of microglia related to killing neurons without affecting the beneficial functions associated with them, as such as scavenging of debris," explains UC Davis' David P. Jenkins, first author of the study.

Presentation 3443-Pos, "Microglial KV1.3 channels as a potential target for Alzheimer's disease," is at 10:30 a.m. on Wednesday, Feb. 29.


'/>"/>

Contact: Ellen Weiss
eweiss@biophysics.org
240-290-5606
American Institute of Physics
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10

Related biology news :

1. Research highlights key role grandmothers play in mother and child nutrition and health
2. AGU journal highlights -- Jan. 13, 2012
3. Highlights of upcoming conference on aldosterone & the ENaC/Degenerin family of ion channels
4. AGU journal highlights -- July 15, 2011
5. AGU journal highlights -- June 23, 2011
6. AGU journal highlights -- June 15, 2011
7. New report highlights diversity and value of Alaskas coastal forests
8. Presidential keynote address and new research highlights from the American Society of Pediatric Otolaryngology meeting
9. AGU journal highlights -- April 13, 2011
10. AGU journal highlights -- March 7, 2011
11. Plenary speech by HHMI professor highlights efforts of scientist-educators
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... a newly coined term for novels and films which focus ... of Copenhagen shows how these fictions serve as a mental ... climate change and imagine other living conditions. , "Global ... the atmosphere; it is also a cultural phenomenon in which ... the films we see. And there are so many of ...
(Date:4/23/2014)... University of Exeter researcher has shed light on how ... in Australia,s remote outback have become reviled as pests ... of the Environment and Sustainability Institute at the University ... camel in Australia, from their historic role helping to ... as unwelcome "invader." , The deserts of the Australian ...
(Date:4/23/2014)... leading a 2 million Food Standards Agency (FSA) project ... and industry workers. , Norovirus outbreaks can rapidly ... batch of frozen strawberries infected 11,000 people in Germany, ... of which strains cause infection and which foods are ... , Researchers will produce data that will help the ...
Breaking Biology News(10 mins):Fiction prepares us for a world changed by global warming 2Fiction prepares us for a world changed by global warming 3How Australia got the hump with 1 million feral camels 2How Australia got the hump with 1 million feral camels 3
... States, (U.S.) predominance in science and technology (S&T) eroded ... China and South Korea--rapidly increased their innovation capacities. According ... Board (NSB), the policy making body of the National ... and Congress, the major Asian economies, taken together, now ...
... , This news release is available in ... transmission at the synapse between neurons is a highly complex, but ... voltage change, the so-called action potential, reaches the synaptic terminal in ... presynaptic neuron. This influx leads to a rise in the intracellular ...
... led by scientists from the University of California, San ... a protein that broadly regulates how genetic information transcribed ... ultimately translated into the myriad of proteins necessary for ... Cell Reports , help explain how a relatively ...
Cached Biology News:US lead in science and technology shrinking 2US lead in science and technology shrinking 3US lead in science and technology shrinking 4Loose coupling between calcium channels and sensors 2Global regulator of mRNA editing found 2
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... pet owners drew up their lists of New Year,s resolutions for ... of my furry companion." Nowadays there are pet salons, dog and ... take the little canine or feline darlings along wherever mommy or ... pricey toys at the pet store. But anyone who has ever ...
(Date:1/14/2014)... DIEGO and BETHESDA, Md. ... are joining together with two institutes from the National ... reliable tools for bringing safer, more effective treatments to ... the National Center for Advancing Translational Sciences (NCATS) and ...
(Date:1/14/2014)... Jan. 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: RXII), ... commercializing innovative therapies addressing major unmet medical needs ... the Notice of Allowance from the United States ... RNAi compounds (sd-rxRNA®), for the treatment of fibrosis. ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... LAUSANNE, Switzerland, September 3 Debiopharm Group, ... with,a focus on the development of prescription drugs ... Life Sciences Award, to Dr Lluis,Quintana-Murci from the ... in the emerging field of evolutionary genetics of,infection. ...
... JERUSALEM, September 3 Oramed Pharmaceuticals,Inc. (OTC ... systems, announced today that Nadav Kidron, its Chief Executive,Officer, is ... Conference on Friday September 11, 2009 at 10:00 a.m. EDT. ... in New York City. , Nadav ...
... , , BEIJING, Sept. 3 ... President Chung Leik Kok, announced today the signing of two (2) ... and Chemical Co., Ltd. (Beijing Oil & Gas). Fauve Intertrade is ... Miami, Florida; and Kuala Lumpur, Malaysia - with offices opening in ...
Cached Biology Technology:The Debiopharm Life Sciences Award Goes to Dr Lluis Quintana-Murci for his Novel and Original Research on the Human Evolutionary Genetics of Infection 2The Debiopharm Life Sciences Award Goes to Dr Lluis Quintana-Murci for his Novel and Original Research on the Human Evolutionary Genetics of Infection 3Oramed Pharmaceuticals to Present at Rodman & Renshaw 11th Annual Healthcare Conference 2Fauve Intertrade Signs Major Energy Contracts in China 2
Human DPPII/QPP/DPP7 Biotinylated Affinity Purified PAb ENTREZ GeneID: 29952...
Human SorCS1 Affinity Purified Polyclonal Ab Protein Family: Neurotrophins...
Human Apolipoprotein B100 Affinity Purified Polyclonal Ab ENTREZ GeneID: 338...
hypertension-related calcium-regulated gene, mRNA...
Biology Products: