Navigation Links
High-resolution atomic imaging of specimens in liquid by TEM using graphene liquid cell
Date:4/9/2012

Daejeon, the Republic of Korea, April 9, 2012The Korea Advanced Institute of Science and Technology (KAIST) announced that a research team from the Department of Materials Science and Engineering has developed a technology that enables scientists and engineers to observe processes occurring in liquid media on the smallest possible scale which is less than a nanometer.

Professor Jeong Yong Lee and Researcher Jong Min Yuk, in collaboration with Professor Paul Alivisatos's and Professor Alex Zettl's groups at the University of California, Berkeley, succeeded in making a graphene liquid cell or capsule, confining an ultra-thin liquid film between layers of graphene, for real-time and in situ imagining of nanoscale processes in fluids with atomic-level resolution by a transmission electron microscope (TEM). Their research was published in the April 6, 2012 issue of Science. (http://www.sciencemag.org/content/336/6077/61.abstract)

The graphene liquid cell (GLC) is composed of two sheets of graphene sandwiched to create a sealed chamber where a platinum growth solution is encapsulated in the form of a thin slice. Each graphene layer has a thickness of one carbon atom, the thinnest membrane that has ever been used to fabricate a liquid cell required for TEM.

The research team peered inside the GLC to observe the growth and dynamics of platinum nanocrystals in solution as they coalesced into a larger size, during which the graphene membrane with the encapsulated liquid remained intact. The researchers from KAIST and the UC Berkeley identified important features in the ongoing process of the nanocrystals' coalescence and their expansion through coalescence to form certain shapes by imaging the phenomena with atomic-level resolution.

Professor Lee said,

"It has now become possible for scientists to observe what is happening in liquids on an atomic level under transmission electron microscopes."

Researcher Yuk, one of the first authors of the paper, explained his research work.

"This research will promote other fields of study related to materials in a fluid stage including physical, chemical, and biological phenomena at the atomic level and promises numerous applications in the future. Pending further studies on liquid microscopy, the full application of a graphene-liquid-cell (GLC) TEM to biological samples is yet to be confirmed. Nonetheless, the GLC is the most effective technique developed today to sustain the natural state of fluid samples or species suspended in the liquid for a TEM imaging."

The transmission electron microscope (TEM), first introduced in the 1930s, produces images at a significantly higher resolution than light microscopes, allowing users to examine the smallest level of physical, chemical, and biological phenomena. Observations by TEM with atomic resolution, however, have been limited to solid and/or frozen samples, and thus it has previously been impossible to study the real time fluid dynamics of liquid phases.

TEM imaging is performed in a high vacuum chamber in which a thin slice of the imaged sample is situated, and an electron beam passes through the slice to create an image. In this process, a liquid medium, unlike solid or frozen samples, evaporates, making it difficult to observe under TEM.

Attempts to produce a liquid capsule have thus far been made with electron-transparent membranes of such materials as silicon nitride or silicon oxide; such liquid capsules are relatively thick (tens to one hundred nanometers), however, resulting in poor electron transmittance with a reduced resolution of only a few nanometers. Silicon nitride is 25 nanometers thick, whereas graphene is only 0.34 nanometers.

Graphene, most commonly found in bulk graphite, is the thinnest material made out of carbon atoms. It has unique properties such as mechanical tensile strength, high flexibility, impermeability to small molecules, and high electrical conductivity. Graphene is an excellent material to hold micro- and nanoscopic objects for observation in a transmission electron microscope by minimizing scattering of the electron beam that irradiates a liquid sample while reducing charging and heating effects.


'/>"/>
Contact: Lan Yoon
hlyoon@kaist.ac.kr
82-423-502-295
The Korea Advanced Institute of Science and Technology (KAIST)
Source:Eurekalert  

Related biology news :

1. Super high-resolution carbon estimates for endangered Madagascar
2. Super high-resolution carbon estimates for endangered Madagascar
3. GigaBlitz will turn high-resolution images of nature into global inventory of organisms, habitats
4. Optical microscope without lenses produces high-resolution 3-D images on a chip
5. New high-resolution carbon mapping techniques provide more accurate results
6. High-resolution imaging expands vision research of live birds of prey
7. Bulletin of the Atomic Scientists publishes Japanese translation of special Fukushima issue
8. Atomic-scale structures of ribosome could help improve antibiotics
9. Worlds smallest atomic clock on sale
10. Insects hold atomic clues about the type of habitats in which they live
11. Atomic weights of 10 elements on periodic table about to make an historic change
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
High-resolution atomic imaging of specimens in liquid by TEM using graphene liquid cell
(Date:6/22/2016)... -- The American College of Medical Genetics and Genomics was once ... one of the fastest-growing trade shows during the Fastest 50 ... Las Vegas . Winners ... each of the following categories: net square feet of paid ... The 2015 ACMG Annual Meeting was ranked 23 out of ...
(Date:6/16/2016)... June 16, 2016 The ... expected to reach USD 1.83 billion by 2024, ... Research, Inc. Technological proliferation and increasing demand in ... expected to drive the market growth. ... The development of advanced multimodal techniques for ...
(Date:6/3/2016)... , June 3, 2016 ... Management) von Nepal ... und Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, ... führend in der Produktion und Implementierung von ... der Ausschreibung im Januar teilgenommen, aber Decatur ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... ... December 01, 2016 , ... PhUSE ... and the popularity of US Single Day Events (SDE) to organize a multiple-day ... 2018, in Raleigh, NC. Topics of the pharmaceutical and life sciences industry will ...
(Date:12/2/2016)... PRUSSIA, PA (PRWEB) , ... December 01, 2016 , ... ... is through industry-wide collaboration, standardization and a beautiful technology experience. All three tenets were ... more than 100 clinical trial leaders from over 40 sponsor, CRO and site organizations ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... dedicated to collaboratively developing improved chemistry, manufacturing and control technologies for the ... UHPLC, with robust, probe-based sampling. , Online liquid chromatography analysis is ...
(Date:12/2/2016)... NEW YORK , Dec. 1, 2016   ... liquid photopurification, announced today that the Company has concluded ... has the right for a 90-day period to acquire ... invoice value of approximately USD 3.7 million.  ... an agreement with Tamarack under which Tamarack will seek ...
Breaking Biology Technology: