Navigation Links
High-level NIH grant goes to professor Nicolas Doucet of INRS
Date:4/16/2014

Professor Nicolas Doucet of the Centre INRSInstitut Armand-Frappier has just received a research grant from the National Institutes of Health (NIH) in the amount of nearly US$600,000. The 5-year grant is to pursue cutting-edge research in the workings of tiny proteins called RNases and to explore their biomedical potential in the field of oncology as well as in inflammation and asthma.

"Receiving a grant at this level is an accomplishment in itself," said Yves Bgin, vice president of research and academic affairs at INRS. "It recognizes outstanding achievement. It is also a sign of the importance and potential of Professor Doucet's work on proteins in movement, further contributing to our understanding of how living beings work."

Professor Doucet will work with two American researchers to develop new computer and experimental tools for studying the dynamics of ribonucleases (RNases) and the processes involved in enzyme catalysis, molecular recognition, and signalling. Their approach is based on experimental computation and molecular dynamics and combines modelling, molecular simulation, and nuclear magnetic resonance (NMR).

Professor Doucet and his team are interested in this family of enzymes and its essential role in the formation of new blood vessels, the degradation of ribonucleic acid (RNA), and in defending against RNA viruses. A better understanding of their molecular function and dynamics could lead to new medications for inhibiting the proliferation of cancer cells or fighting a number of pathogens. The new methodologies they develop could also be used to study other enzyme systems.

Professor Doucet's NMR characterization of the ribonuclease superfamily project is part of the NIH-funded "Conformational sub-states in enzyme catalysis: Applications to the ribonuclease family" research initiative being conducted in partnership with the University of Pittsburgh's Professor Chakra Chennubhotla and Professor Pratul K. Agarwal of Oak Ridge National Laboratory in Tennessee.


'/>"/>

Contact: Gisèle Bolduc
gisele.bolduc@adm.inrs.ca
418-654-2501
INRS
Source:Eurekalert

Related biology news :

1. TGen Dr. Michael Barrett awarded $200,000 grant at national cancer conference in San Diego
2. $1.7 million NIH grant to Wayne State to discover treatments for methamphetamine-abuse
3. Academy of Natural Sciences receives major grant for program to protect drinking water
4. National Cancer Institute awards $2.2 million grant to Jackson Professor Yijun Ruan
5. New $1.5 million grant boosts local efforts to save lives of moms and babies during childbirth
6. The search is on for a hepatitis B drug, thanks to a million dollars in NIH grants to SLU
7. American Society of Hematology awards third round of Bridge Grants
8. IDRI receives $3.4 million grant extension for TB drug discovery
9. Wayne State receives grant to advance ecological restoration efforts in the Great Lakes
10. NIH grants up to $28 million to group led by Scripps Research for work on ebola treatment
11. Jump start for frontier projects: The 2014 HFSP Research Grants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2016)... 2016 Einzigartige ... und Stimmerkennung mit Passwörtern     ... MESG ), ein führender Anbieter digitaler Kommunikationsdienste, ... SpeechPro zusammenarbeitet, um erstmals dessen Biometrietechnologie einzusetzen. ... Möglichkeit angeboten, im Rahmen mobiler Apps neben ...
(Date:3/21/2016)... WAKEFIELD, Massachusetts , March 22, 2016 ... and facial recognition with passcodes for superior security ... MESG ), a leading provider of secure digital communications ... pilot their biometric technology and offer enterprise customers, particularly ... provide secure facial recognition and voice authentication within a ...
(Date:3/15/2016)... New York , March 15, 2016 ... new market report published by Transparency Market Research "Digital Door ... Trends and Forecast 2015 - 2023," the global digital door ... US$ 731.9 Mn in 2014 and is forecast to grow ... 2023. Growth of micro, small and medium enterprises (MSMEs) across ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... ... April 29, 2016 , ... Intelligent Implant Systems announced today ... via 510(k) for sale in the United States. These components expand the capabilities ... With one-level sales beginning in October of 2015, the company has seen significant ...
(Date:4/28/2016)... Hill, Conn. (PRWEB) , ... April 28, 2016 ... ... of financing and ongoing support for Connecticut's innovative, growing companies, today announced the ... digital health and financial technology (fintech) companies. , “VentureClash looks to ...
(Date:4/27/2016)... ... ... Cambridge Semantics, the leading provider of Smart Data analytic and ... named to The Silicon Review’s “20 Fastest Growing Big Data Companies of 2016.” ... needs of end users facing some of the most complex data challenges in the ...
(Date:4/27/2016)... April 27, 2016 NanoStruck ... (OTCPink: NSKQB) ( Frankfurt : 8NSK) ... Pressemitteilung vom 13. August 2015 die Genehmigung von ... um zusätzliche 200.000.000 Einheiten auf 400.000.000 Einheiten zu ... bringen. Davon wurden 157.900.000 Einheiten mit dem ersten ...
Breaking Biology Technology: