Navigation Links
High folate gestational and post-weaning diets in Wistar rat offspring
Date:7/12/2013

During pregnancy, women are normally advised to take high amounts of multivitamin supplements. In particular, folate is recommended to reduce the risk of neural tube defects in newborns. The problem is that, although vitamins are critical in fetal development, high vitamin doses during pregnancy may cause undesired effects on the offspring later in life (in rats, an obesogenic phenotype is typically observed). A study in the July issue of the journal Epigenetics suggests that feeding the pups a similar high-folate diet can prevent the obesogenic phenotype of mature offspring from rats fed a high-folate diet during pregnancy. The authors explain that the increase in folate content in the pup diet has epigenetic effects (molecular changes in genes without any changes in the DNA sequence) on the hypothalamic mechanisms that regulate food intake. The study, performed in rats and authored by researchers at the Faculty of Medicine from the University of Toronto, has relevance in humans as the effect of increasing amounts of vitamins, especially folate, consumed during pregnancy may have undiscovered later-life effect in the progeny. For the full report, see http://www.landesbioscience.com/journals/epigenetics/article/24948/.


'/>"/>

Contact: Andrew Thompson
andrew@landesbioscience.com
Landes Bioscience
Source:Eurekalert

Page: 1

Related biology news :

1. Supplement use predicts folate status in Canadian women
2. Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients
3. The effect of catch-up growth by various diets and resveratrol intervention on bone status
4. New study compares diets for weight management in obese children
5. Researchers find potential dark side to diets high in beta-carotene
6. Pasta made from green banana flour a tasty alternative for gluten-free diets
7. Sugar-sweetened drinks are not replacing milk in kids diets
8. Diets high in salt could deplete calcium in the body: UAlberta research
9. Feces fossils yield new insights into ancient diets and thrifty genes
10. Childrens healthy diets lead to healthier IQ
11. Study finds maize in diets of people in coastal Peru dates to 5,000 years ago
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... Lithuania , May 3, 2016  Neurotechnology, ... released the MegaMatcher Automated Biometric Identification System ... of large-scale multi-biometric projects. MegaMatcher ABIS can process ... accuracy using any combination of fingerprint, face or ... MegaMatcher SDK and MegaMatcher Accelerator ...
(Date:4/19/2016)... UAE, April 20, 2016 The ... as a compact web-based "all-in-one" system solution for all ... fingerprint reader or the door interface with integration authorization ... access control systems. The minimal dimensions of the access ... into the building installations offer considerable freedom of design ...
(Date:3/31/2016)... 31, 2016   ... the "Company") LegacyXChange is excited to release ... soon to be launched online site for trading 100% ... ) will also provide potential shareholders a sense of ... to an industry that is notorious for fraud. The ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... ... 2016 , ... STACS DNA Inc., the sample tracking software company, today announced ... has joined STACS DNA as a Field Application Specialist. , “I am thrilled ... COO of STACS DNA. “In further expanding our capacity as a scientific integrator, Hays ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
(Date:6/23/2016)... , June 23, 2016 ... Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 Published ... the peer-reviewed journal from touchONCOLOGY, Andrew D ... cost of cancer care is placing an increasing ... of expensive biologic therapies. With the patents on ...
Breaking Biology Technology: