Navigation Links
High folate gestational and post-weaning diets in Wistar rat offspring

During pregnancy, women are normally advised to take high amounts of multivitamin supplements. In particular, folate is recommended to reduce the risk of neural tube defects in newborns. The problem is that, although vitamins are critical in fetal development, high vitamin doses during pregnancy may cause undesired effects on the offspring later in life (in rats, an obesogenic phenotype is typically observed). A study in the July issue of the journal Epigenetics suggests that feeding the pups a similar high-folate diet can prevent the obesogenic phenotype of mature offspring from rats fed a high-folate diet during pregnancy. The authors explain that the increase in folate content in the pup diet has epigenetic effects (molecular changes in genes without any changes in the DNA sequence) on the hypothalamic mechanisms that regulate food intake. The study, performed in rats and authored by researchers at the Faculty of Medicine from the University of Toronto, has relevance in humans as the effect of increasing amounts of vitamins, especially folate, consumed during pregnancy may have undiscovered later-life effect in the progeny. For the full report, see


Contact: Andrew Thompson
Landes Bioscience

Page: 1

Related biology news :

1. Supplement use predicts folate status in Canadian women
2. Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients
3. The effect of catch-up growth by various diets and resveratrol intervention on bone status
4. New study compares diets for weight management in obese children
5. Researchers find potential dark side to diets high in beta-carotene
6. Pasta made from green banana flour a tasty alternative for gluten-free diets
7. Sugar-sweetened drinks are not replacing milk in kids diets
8. Diets high in salt could deplete calcium in the body: UAlberta research
9. Feces fossils yield new insights into ancient diets and thrifty genes
10. Childrens healthy diets lead to healthier IQ
11. Study finds maize in diets of people in coastal Peru dates to 5,000 years ago
Post Your Comments:
(Date:11/26/2015)... Research and Markets ( ) has ... - Technology and Patent Infringement Risk Analysis" report ... --> Fingerprint sensors using capacitive technology represent ... sensor vendor Idex forecasts an increase of 360% of ... and of the fingerprint sensor market between 2014 and ...
(Date:11/20/2015)... November 20, 2015 NXTD ) ... on the growing mobile commerce market and creator of ... Pereira , was recently interviewed on The RedChip ... on this weekend on Bloomberg Europe , Bloomberg ... --> NXTD ) ("NXT-ID" or the "Company"), ...
(Date:11/19/2015)...  Based on its in-depth analysis of the biometric ... the 2015 Global Frost & Sullivan Award for Product ... this award to the company that has developed the ... the market it serves. The award recognizes the extent ... customer base demands, the overall impact it has in ...
Breaking Biology News(10 mins):
(Date:11/28/2015)... South Korea (PRWEB) , ... November 28, 2015 , ... ... class of eco-friendly avian, porcine and rodent control solutions , ... as peppermint and cinnamon oil, works across all sensory modalities including visual, smell, taste ...
(Date:11/27/2015)... Kingdom , Nov. 27, 2015 /PRNewswire/--  Mallinckrodt plc ... company, announced today that it has closed the sale ... business to Guerbet (GBT- NYSE Euronext) in a transaction ... encompassed four manufacturing facilities and a total of approximately ... in the St. Louis area. ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... includes over 2,000 technical presentations offered in symposia, oral sessions, workshops, awards, and ... covers a wide range of applications such as, but not limited to, biotechnology, ...
(Date:11/27/2015)... India , November 27, 2015 /PRNewswire/ ... --> Growing popularity of companion diagnostics ... in cancer biomarkers market with pharmaceutical companies ... in-demand companion diagnostic tests. ... --> Complete report on global cancer ...
Breaking Biology Technology: