Navigation Links
High-fat diets inflame fat tissue around blood vessels, contribute to heart disease
Date:2/18/2009

CINCINNATIA study by researchers at the University of Cincinnati (UC) shows that high-fat diets, even if consumed for a short amount of time, can inflame fat tissue surrounding blood vessels, possibly contributing to cardiovascular disease.

These findings will be published in the Feb. 20 edition of the American Heart Association journal Circulation Research.

Neal Weintraub, MD, and colleagues examined adipose tissueor fatsurrounding the coronary arteries of humans. The researchers found these fat cells to be highly inflamed, suggesting that they could trigger inflammation of the blood vessels, an important component of atherosclerosis.

They also found that the inflammation of fat tissues around the arteries of mice is increased by feeding the animals a high-fat diet for just two weeks.

"This is independent of weight gain or blood lipidscholesterol levels," says Weintraub, senior author of the study and chair of the cardiovascular diseases division at UC.

Weintraub says that high fat diets contribute to atherosclerosisor the hardening of arteriesin a number of ways.

"Elevated blood lipidsor cholesterol levelscan worsen with the intake of high fat diets, and this is known to contribute to atherosclerosis," he says. "However, many patients who consume high fat diets do not exhibit abnormal lipid profiles but still develop atherosclerosis nonetheless.

"These new findings suggest a direct link between poor dietary habits and inflammation of blood vessels, mediated by the fat cells surrounding the blood vessel wall."

Weintraub adds that the diet fed to the mouse models was not unlike the diets consumed by many Americans.

"It produced striking abnormalities of the fat tissue surrounding blood vessels in a very short period of time," he says. "This is a warning to those who say there isn't a problem because their weight and cholesterol levels are under control. Lipid profiles
'/>"/>

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati
Source:Eurekalert

Page: 1 2

Related biology news :

1. New discovery could reduce the health risk of high-fat foods
2. Scientists discover why a mothers high-fat diet contributes to obesity in her children
3. Sea otter study reveals striking variability in diets and feeding strategies
4. New study shows low-fat diets more likely to reduce risk of heart disease than low-carb diets
5. U of M finds teens who eat breakfast daily eat healthier diets than those who skip breakfast
6. Eliminating soda from school diets does not affect overall consumption
7. Low-carb diets can affect dieters cognition skills
8. Nutrigenomics -- developing personalized diets for disease prevention
9. Scientists find link between inflamed gums and heart disease
10. A step toward tissue-engineered heart structures for children
11. Researchers create system to build transplant tissue
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... and decisions of the Nomenclature Section of the XVIII ... July 2011. This meeting is held every six years ... the rules for naming algae, fungi and plants get ... naming the organisms they study. This is the primary ... for algae, fungi, and plants, which was published in ...
(Date:8/31/2014)... A fast-sensitive "electronic-nose" for sniffing the highly infectious bacteria ... stomach cramps, has been developed by a team at ... the research team has demonstrated that it is possible ... which would lead to rapid diagnosis of the ... could be possible to identify different strains of the ...
(Date:8/31/2014)... of satellite data from the last 19 years reveals that ... the coast of Antarctica to rise by 2cm more than ... of Southampton detected the rapid rise in sea-level by studying ... million square kilometres. , The melting of the ... has contributed an excess of around 350 gigatonnes of freshwater ...
Breaking Biology News(10 mins):Week-long meeting on naming algae, fungi, and plants recorded for posterity 2Scientists develop 'electronic nose' for rapid detection of C. diff infection 2
... research shows an increased risk of ischemic stroke in postmenopausal ... found in baked goods, fried foods, and packaged products. Study ... journal published by Wiley-Blackwell on behalf of the American Neurological ... the stroke risk caused by a diet high in trans ...
... NY, February 29, 2012Although industrial parks are often ... which they reside, they can also consume environmental ... affect human health and quality of life. A ... ( http://www.liebertpub.com/ees ), a peer-reviewed journal from ...
... supercomputer has completed the first phase of an ... powerful scientific computing systems in the world. ... this month. The testing suite included leading scientific ... fusion, and combustion. Jaguar, manufactured by Cray ...
Cached Biology News:Postmenopausal women at greater risk of stroke from high trans fat intake 2Can industrial parks be more environmentally friendly? 2ORNL completes first phase of Titan supercomputer transition 2
(Date:9/2/2014)... Calif. , Sept. 2, 2014  Xencor, ... biopharmaceutical company developing engineered monoclonal antibodies for the ... and cancer, today announced the appointment of ... development and the appointment of Lloyd Rowland ... general counsel. "Debra,s expertise in ...
(Date:9/2/2014)... Sept. 2, 2014  Spherix Incorporated (SPEX) -- an intellectual property ... intellectual property, today announced that the United States Patent ... Company in the month of August that are part ... The issued patents are: , ... August 19, 2014; and , U.S.RE45,095 issued August ...
(Date:9/1/2014)... The Collaborative R&D Terms and ... comprehensive understanding and unprecedented access to the collaborative ... worlds leading life science companies. , The report ... and why companies enter collaborative R&D deals. , ... deals terms provides critical insight into the negotiation ...
(Date:8/30/2014)... Dallas, TX (PRWEB) August 31, 2014 ... Industry is a professional and in-depth study on ... industry in Global and China. , The report ... definitions, applications and industry chain structure. Global market ... with a focus on history, developments, trends and ...
Breaking Biology Technology:Xencor Appoints Debra Zack, M.D., Ph.D., Vice President, Clinical Development and Lloyd Rowland, Senior Vice President, Chief Compliance Officer and General Counsel 2Xencor Appoints Debra Zack, M.D., Ph.D., Vice President, Clinical Development and Lloyd Rowland, Senior Vice President, Chief Compliance Officer and General Counsel 3United States Patent & Trademark Office Issues Three New Standard Essential Patents to Spherix 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 3Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 4Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3
... Kauten is taking direct aim at three unfavorable metrics, and ... , ,Kauten, CEO of QBI Life Sciences , recently ... Polymeric Micelles, a core product. The screening, which employed UGT1A1, ... is used to determine whether a drug will become active ...
... that is developing technologies for the $6 billion worldwide wound ... , ,The company, which was honored during an awards ceremony ... of 27 finalists that presented business plans to a panel ... which drew 200 entries, it will collect prizes of at ...
... Telecommunications, Inc. has introduced the Enhanced Mail Guardian, ... for organizational networks. , ,Enhanced Mail Guardian's features include ... be customized to handle encrypted e-mails that are specific ... sort e-mails and attachments based on key words like ...
Cached Biology Technology:QBI's PreserveX product passes initial test 2QBI's PreserveX product passes initial test 3MatriLab wins Governor's Business Plan Contest 2MatriLab wins Governor's Business Plan Contest 3MatriLab wins Governor's Business Plan Contest 4
... 1, active MW: 34.2kDa Formulation: 10mM ... Brij-35, 1mM dithiothreitiol with 50% glycerol ... to the Certificate of Analysis for ... salt precipitation followed by gel filtration ...
MitoScreen (JC-1) Kit , 100 tests Consult technical datasheet for details....
Thermal Printer Paper for Monolight(tm) Luminometer 1 each...
Conjugate Quality Control Evaluation Specificity: Conjugate Quality Control Evaluation ...
Biology Products: