Navigation Links
High-fat diet during puberty linked to breast cancer risk later in life
Date:8/31/2010

EAST LANSING, Mich. Girls eating a high-fat diet during puberty, even those who do not become overweight or obese, may be at a greater risk of developing breast cancer later in life, according to Michigan State University researchers.

The implications that a high-fat diet may have detrimental effects independent of its effect to cause obesity could drive new cancer prevention efforts.

The findings come from research at MSU's Breast Cancer and the Environment Research Center, established in 2003 and funded through 2010 by the National Institute of Environmental Health Sciences and the National Cancer Institute.

Physiology professor Sandra Haslam, director of the center, and Richard Schwartz, microbiology professor and associate dean in the College of Natural Science, are now expanding that research with a new, five-year, $2.3 million federal grant. They will use that funding to continue their work studying the impact of prenatal-to-adult environmental exposures that predispose women to breast cancer as part of the extended nationwide Breast Cancer and the Environment Research Program.

"The pubertal time period is crucial, as this is when the basic framework is created for mammary gland development," Haslam said. "What we are seeing from preliminary research in animals is that a high-fat diet during puberty can lead to the production of inflammatory products in the mammary glands of adults, which can promote cancer growth."

The work builds on the team's previous research that found the hormone progesterone activates genes that trigger inflammation in the mammary gland; that inflammation may be a key factor in increasing the risk of breast cancer. Those findings were published last year in the Journal of Steroid Biochemistry and Molecular Biology.

Haslam and Schwartz discovered that a high-fat diet during puberty produced many of the same effects seen as part of their progesterone research.

"Under
'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Scientists discover why a mothers high-fat diet contributes to obesity in her children
2. High-fat diets inflame fat tissue around blood vessels, contribute to heart disease
3. Researchers uncover obesity gene involved in weight gain response to high-fat diet
4. High-fat diet affects physical and memory abilities of rats after 9 days
5. Do high-fat diets make us stupid and lazy?
6. TV bombards children with commercials for high-fat and high-sugar foods
7. Flavonoids in orange juice suppress oxidative stress from high-fat, high-carb meal
8. Experts discuss climate change during UH lecture series
9. During exercise, the human brain shifts into high gear on alternative energy
10. New study indicates link between weight gains during pregnancy and dieting history
11. Rethinking who should be considered essential during a pandemic flu outbreak
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/2/2015)... -- According to preliminary estimates Fingerprint Cards, ... than 125 MSEK. This exceeds the guidance provided by ... for Q1 2015 would be in line with the ... The operating result for the first quarter is estimated ... will as previously communicated be published on May 21. ...
(Date:4/1/2015)... OXFORD, Conn. , Apr. 1, 2015  NXT-ID, ... a biometric authentication company focused on the growing mobile ... number of Wocket smart wallets is underway to early ... early access group includes usage at retail outlets including ... CVS Pharmacy. Users report Wocket was accepted at all ...
(Date:3/31/2015)... 31, 2015  Elephant Talk Communications Corp. (NYSE MKT: ... of Software Defined Network Architecture (ET Software DNA® 2.0) ... of approximately $20.4 million for the year ended December ... for the year ended December 31, 2013. ... had completed its multi-year transition away from its legacy ...
Breaking Biology News(10 mins):Fingerprint Cards Revises Revenues for Q1 2015 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... Health (NIH) today announced the first awards for its ... efforts to explore how complex communities of microbes interact ... The funding, estimated to be up to approximately $21.2 ... computational tools, coordination of data analysis and an examination ...
... in age-related macular degeneration, the most common cause of ... today in the Lancet , adds to the ... (AMD), which the researchers believe should ultimately lead to ... people aged 80 years or older are affected by ...
... for Medical Research today announced that scientists have created a ... cells from programmed cell death, and converts it into a ... featured article in the October 7 edition of Cancer ... Bcl-2 protein has long been implicated in protecting cancer cells ...
Cached Biology News:Human Microbiome Project awards funds for technology development, data analysis and ethical research 2Human Microbiome Project awards funds for technology development, data analysis and ethical research 3Human Microbiome Project awards funds for technology development, data analysis and ethical research 4Genetic finding implicates innate immune system in major cause of blindness 2
(Date:4/30/2015)... April 30, 2015 - ... Biotechnology Company   Shire (LSE: SHP, ... three months to March 31, 2015. ... million +9% +13% Total revenues $1,488 million +11% +15% ... GAAP operating income from continuing operations $475 million +55% ...
(Date:4/30/2015)... April 30, 2015 SureClinical, a leader ... I. Morris has joined SureClinical’s executive team as Chief ... biotech and technology executive with over 25 years in ... companies. , Ms. Morris joins SureClinical from Marrone ... She was CFO of MBI from its founding in ...
(Date:4/29/2015)... April 29, 2015 SPIE DSS, ... imaging on the East Coast, reaffirmed its value last ... applications developers, and industry suppliers to meet and advance ... multiple applications. , The event included 55 conferences in ... scientific sensing and imaging -- and an exhibition showcasing ...
(Date:4/29/2015)... Colo. , April 29, 2015 ... providers of cartilage, cellular, bone, skin and soft-tissue ... care to advance patient healing, announced the launch ... Centers for Medicare & Medicaid Services (CMS) also ... from the low-cost to the high-cost category for ...
Breaking Biology Technology:Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 2Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 3Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 4Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 5Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 6Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 7Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 8Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 9Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 10Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 11Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 12Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 13Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 14Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 15Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 16Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 17Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 18Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 19Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 20Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 21Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 22Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 23Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 24Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 25Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 26Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 27Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 28Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 29Julie I. Morris Joins SureClinical as Chief Financial Officer 2SPIE DSS provides venue for collaboration vital to research, applications advances 2SPIE DSS provides venue for collaboration vital to research, applications advances 3SPIE DSS provides venue for collaboration vital to research, applications advances 4AlloSource Announces New Possibilities In Wound Care 2
... phase of this personalized medicine initiativeTAMPA, Fla., ... Center , funded through an assistance agreement that ... Army Medical Research & Materiel Command (USAMRMC) ... Center (TATRC), will be conducting a multi-institutional ...
... England, April 24 PharmaVentures Ltd, announced,today that ... Inc. to advise and assist in,divesting its world ... The engagement will utilise PharmaVentures, pharmaceutical,transactions experience in ... an integrated, state-of-the-art small molecule and biological,discovery centre. ...
... Ill. A new study reveals that contrary ... are prone to breakage when new species are formed ... The functions of genes found in these "breakpoint regions" ... This suggests that chromosomal organization plays an important evolutionary ...
Cached Biology Technology:NFGC Conducts Multi-Institutional Research Project in Ovarian Cancer 2NFGC Conducts Multi-Institutional Research Project in Ovarian Cancer 3Merck Engages PharmaVentures to Assist in the Divestment of its Italian Research Centre IRBM 2Chromosome breakpoints contribute to genetic variation 2Chromosome breakpoints contribute to genetic variation 3
... is collected from fasted mixed breed, mixed sex ... Anticoagulants: N-02: Citrate N-04: ... N-08: Potassium Oxalate N-10: EDTA ... ACD N-07: CPD N-09: ...
Collected from normal, healthy animals in carefully maintained standing herds of US orgin. Pricing: $45/unit for 1 - 10 units...
... Kit is designed to purify double-stranded DNA (dsDNA) ... and PCR. The process is simple and fast. ... g can be efficiently purified and concentrated. The ... is bound to the Microfilter Cartridge in the ...
NORMAL DONOR DONKEY SERUM...
Biology Products: