Navigation Links
High blood pressure in older adults traced to gene's effects in blood vessels
Date:1/10/2008

n, but under these conditions, the vessel lining releases a substance, nitric oxide, that won't allow the cells to divide. The smooth muscle cells' resulting growth pushes inward, putting pressure on the lumen and restricting blood flow, resulting in high blood pressure.

Profilin 1 is a tool that triggers events that make the vessel more constricted and leads to the signal that results in vascular remodeling. Because we have understood the pathway of the disease process, we might be able to control vascular remodeling, Hassanain said.

Once a vessel is remodeled, more trouble is typically ahead. Diseased vessels are often characterized by injuries to the endothelium, where the lining of the vessel loses its protective layer. Once the lining is injured and vulnerable, smooth muscle cells will start to migrate inward, creating sticking points for fats, debris and other blood remnants.

That's the first hint of plaque. The smooth muscle cell migration is the tip of the iceberg of the plaque, Hassanain said. We're talking about all vessels, but when we're talking about this narrowing effect in the brain, this could lead to stroke, and in the coronary artery, it could lead to heart attack. It's all the same phenomenon.


'/>"/>

Contact: Hamdy Hassanain
hamdy.hassanain@osumc.edu
614-292-1062
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. High blood pressure, low energy -- a recipe for heart failure
2. Right breakfast bread keeps blood sugar in check all day
3. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
4. Folic acid lowers blood arsenic levels, according to Mailman School of Public Health study
5. Folic acid lowers blood arsenic levels in Bangladesh
6. Study reveals a key to blood vessel growth and possible drug target
7. Expecting an afternoon nap can reduce blood pressure
8. MIT: blood may help us think
9. Immune cells promote blood vessel formation in mouse endometriosis
10. Elevated nitric oxide in blood is key to high altitude function for Tibetans
11. Fine-tuning lasers to destroy blood-borne diseases like AIDS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... SAN DIEGO , Dec. 9, 2014 ... and collaboration catalyst that provides the connective tissue that ... by enabling them to easily share client-level information; earned ... Foundation to expand to organizations serving seniors aging in ... San Diego" partner on December 11 th 4-6p. ...
(Date:12/4/2014)... 3, 2014  Crossmatch™, a leading provider of ... DigitalPersona ® Pro Enterprise software and U.are.U ... throughout First Bank branch locations in ... and Virginia. First Bank, a progressive community ... North Carolina , selected the Crossmatch biometrics-based ...
(Date:11/21/2014)... Nov. 20, 2014 Strict laws against distracted ... piloting the North American and European automotive sector towards ... gesture recognition systems that are intuitive and able to ... the industry. New analysis from Frost ... Market in Europe and ...
Breaking Biology News(10 mins):Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 2Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 4
... Optiqua Technologies Pte Ltd is collaborating with Nanyang ... in biomolecular sciences and sensor technology. Optiqua, ... provides the international water industry with innovative products ... detection of contaminants in water. The sensor technology ...
... Oregon Health & Science University Doernbecher Children,s Hospital have defined ... sarcoma. In a study published today as the Featured Article ... childhood and adult sarcomas are linked in their biology, mutations ... findings may lead to non-chemotherapy medicines that can inhibit "molecular ...
... paper published today in PNAS, scientists from the European ... insights into the workings of enzymes from a group ... that causes tuberculosis. The new findings present possible new ... but leave other microorganisms, which are beneficial to us, ...
Cached Biology News:Optiqua-NTU partnership to develop next-generation sensor technology 2Scientists discover cell of origin for childhood muscle cancer 22 in 1: Multi-tasking protein provides new approaches for anti-tuberculosis drugs 2
(Date:12/22/2014)... 2014 /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: REPCF) ... on the development of autologous cell therapies, announced today ... of Calgary in conjunction with co-authors from Kyoto University ... the company,s ongoing clinical research using dermal sheath cup ... The paper entitled " Hair Follicle Dermal ...
(Date:12/22/2014)... Dec. 22, 2014 GenomeDx Biosciences today announced ... Cancer Classifier, a genomic test for prostate cancer, was ... men managed by radical prostatectomy without adjuvant therapy. Although ... relatively uncommon, using tumor genomics to identify these men ... is an important advance. The study has been ...
(Date:12/22/2014)... 2014 The American Journal ... original research, reviews and editorials addressing developments and ... today published a provocative article exploring the role ... and potential treatment of prostate cancer. , ... proposes the possibility that there could be a ...
(Date:12/22/2014)... (PRWEB) December 22, 2014 Fertility Associates ... Donor Egg Bank USA , a network of more ... Through this partnership, patients have fast access to a ... vitro fertilization, IVF . Fertility Associates of Memphis is ... this fertility treatment option. , Dr. William Kutteh ...
Breaking Biology Technology:Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3
... 1, 2012 Unigene Laboratories, Inc. (OTCBB: ... Drug Delivery Partnerships™ ("DDP") Innovation Award in the Industry ... advances in the oral delivery of peptides.  ... and selected by conference attendees, including leading scientists, pharmaceutical ...
...  Generex Biotechnology Corporation (OTCBB: GNBT.OB) announced today that ... been awarded a Japanese Patent centering on its ... A number of products developed with this technology ... to secure the novel Antigen Express vaccine technology ...
... MINNEAPOLIS, February 1, 2012 Alchem International ... The sales and marketing office will be spearheaded by ... This office will cater to the rapidly growing demand ... their purified derivatives for the supplement, pharmaceutical and cosmetic ...
Cached Biology Technology:Unigene Receives 2012 Drug Delivery Partnerships Industry Achievement Award 2Unigene Receives 2012 Drug Delivery Partnerships Industry Achievement Award 3Unigene Receives 2012 Drug Delivery Partnerships Industry Achievement Award 4Unigene Receives 2012 Drug Delivery Partnerships Industry Achievement Award 5Generex Announces Patent Award for its Core Vaccine Technologies in Japan 2Generex Announces Patent Award for its Core Vaccine Technologies in Japan 3Generex Announces Patent Award for its Core Vaccine Technologies in Japan 4Alchem International Opens Sales and Marketing Office in the U.S. 2
...
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
Experion StdSens chips are the microfluidic chips used to perform standard-sensitivity RNA analysis (nanogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to...
...
Biology Products: