Navigation Links
Hidden strains of HPV found in 'virus-negative' genital warts
Date:7/11/2013

There are 170 established HPV types. Cancerous human papillomavirus (HPV) viruses are the main cause of cervical cancer, and are found in close to 100% of cervical tumors.

Cervical cancer and genital warts are caused by HPV. However, testing for the virus using standard techniques can sometimes give a negative result -- in these cases, the condylomas are called 'virus-negative' warts.

In a new study published in Virology, researchers assessed the DNA found in samples taken from 40 patients with 'virus-negative' genital warts. Through a general DNA sequencing approach, the researchers showed that several of the negative samples did in fact contain HPV DNA.

This means that virus-negative warts can harbor small amounts of more distantly related viruses that escaped previous detection. According to the research, there is a diverse pool of previously unknown HPV types that infect humans and are detectable on genital warts.

The findings have implications for the knowledge of diversity of HPV types, as these viruses are currently undetectable using traditional testing methods.

Ten pools of four samples taken from virus-negative warts were tested using genetic material straight from the patient -- including viral, bacterial and human DNA. Five of the pools contained HPV, and three of these contained new strains of the virus.

Altogether, 1337 pieces of HPV-related DNA were detected, representing 23 new types of HPV, 10 established types of HPV and two known HPV DNA sequences.

This new style of testing has highlighted previously unknown forms of the virus. As such, we learn more about the evolution of different HPV types. It is possible that the previously unknown forms of the virus do not cause condyloma but may be secondary invaders of condyloma.


'/>"/>

Contact: Sacha Boucherie
s.boucherie@elsevier.com
31-204-853-564
Elsevier
Source:Eurekalert

Page: 1

Related biology news :

1. Hidden effects of climate change may threaten eelgrass meadows
2. Hidden layer of genome unveils how plants may adapt to environments throughout the world
3. Microbiologists eavesdrop on the hidden lives of microbes
4. Immune system molecule with hidden talents
5. MBL scientists to explore hidden realm of microbes, viruses beneath the ocean floor
6. Hidden secrets in the worlds most northerly rainforests
7. Blowing in the wind: How hidden flower features are crucial for bees
8. Elephant seal tracking reveals hidden lives of deep-diving animals
9. First satellite tag study for manta rays reveals habits and hidden journeys of ocean giants
10. Researchers create method to rapidly identify specific strains of illness
11. Researchers develop a faster method to identify Salmonella strains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/1/2017)... Massachusetts , February 1, 2017 IDTechEx ... events on emerging technology, announces the availability of a new report, ... Continue Reading ... ... in industrial and collaborative robots. Source: IDTechEx Report "Sensors for Robotics: ...
(Date:1/26/2017)... 2017  Crossmatch, a leading provider of security and ... at combatting fraud, waste and abuse in assistance operations ... Action on Disaster Relief conference in Panama ... agencies and foreign assistance organizations throughout Latin ... are a largely unacknowledged problem in the foreign assistance ...
(Date:1/24/2017)... YORK , Jan. 24, 2017 ... study of the laboratory use of nuclear magnetic ... 363 experienced end-users and profiled current practices, developments, ... years, as well as growth and opportunities. These ... Instrument suppliers, NMR instruments, needs and innovation requirements, ...
Breaking Biology News(10 mins):
(Date:2/23/2017)... ... February 23, 2017 , ... ... clearance to begin marketing the SPEAC® System, the Brain Sentinel® Seizure Monitoring and ... or in healthcare facilities during periods of rest. A lightweight, non-invasive monitor is ...
(Date:2/23/2017)... ... 23, 2017 , ... David Nolte, PhD accepted Purdue University’s ... Purdue Research Park of West Lafayette, Indiana. , The top commercialization award ... and success with, commercializing discoveries from Purdue research. “This award is truly an ...
(Date:2/23/2017)... ... February 23, 2017 , ... The Greater Gift Initiative, Inc ... with Compass Research . GGI's mission is to advance global health and highlight ... in need in honor of each clinical trial volunteer. The vision of GGI is ...
(Date:2/23/2017)... Feb. 23, 2017 Aviva Systems Biology ... the acquisition of GenWay Biotech Incorporated, a protein ... and product offering for both the research and ... growth and enhance capabilities for both entities. GenWay,s 18 ... assays will nicely complement ASB,s objective to become ...
Breaking Biology Technology: