Navigation Links
Hidden strains of HPV found in 'virus-negative' genital warts
Date:7/11/2013

There are 170 established HPV types. Cancerous human papillomavirus (HPV) viruses are the main cause of cervical cancer, and are found in close to 100% of cervical tumors.

Cervical cancer and genital warts are caused by HPV. However, testing for the virus using standard techniques can sometimes give a negative result -- in these cases, the condylomas are called 'virus-negative' warts.

In a new study published in Virology, researchers assessed the DNA found in samples taken from 40 patients with 'virus-negative' genital warts. Through a general DNA sequencing approach, the researchers showed that several of the negative samples did in fact contain HPV DNA.

This means that virus-negative warts can harbor small amounts of more distantly related viruses that escaped previous detection. According to the research, there is a diverse pool of previously unknown HPV types that infect humans and are detectable on genital warts.

The findings have implications for the knowledge of diversity of HPV types, as these viruses are currently undetectable using traditional testing methods.

Ten pools of four samples taken from virus-negative warts were tested using genetic material straight from the patient -- including viral, bacterial and human DNA. Five of the pools contained HPV, and three of these contained new strains of the virus.

Altogether, 1337 pieces of HPV-related DNA were detected, representing 23 new types of HPV, 10 established types of HPV and two known HPV DNA sequences.

This new style of testing has highlighted previously unknown forms of the virus. As such, we learn more about the evolution of different HPV types. It is possible that the previously unknown forms of the virus do not cause condyloma but may be secondary invaders of condyloma.


'/>"/>

Contact: Sacha Boucherie
s.boucherie@elsevier.com
31-204-853-564
Elsevier
Source:Eurekalert

Page: 1

Related biology news :

1. Hidden effects of climate change may threaten eelgrass meadows
2. Hidden layer of genome unveils how plants may adapt to environments throughout the world
3. Microbiologists eavesdrop on the hidden lives of microbes
4. Immune system molecule with hidden talents
5. MBL scientists to explore hidden realm of microbes, viruses beneath the ocean floor
6. Hidden secrets in the worlds most northerly rainforests
7. Blowing in the wind: How hidden flower features are crucial for bees
8. Elephant seal tracking reveals hidden lives of deep-diving animals
9. First satellite tag study for manta rays reveals habits and hidden journeys of ocean giants
10. Researchers create method to rapidly identify specific strains of illness
11. Researchers develop a faster method to identify Salmonella strains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/12/2016)... 2016 WearablesResearch.com , a brand of ... results from the Q1 wave of its quarterly wearables ... consumers, receptivity to a program where they would receive ... insurance company. "We were surprised to see ... Michael LaColla , CEO of Troubadour Research, "primarily because ...
(Date:4/28/2016)... GOTHENBURG, Sweden , April 28, 2016 ... 1,491.2 M (139.9), up 966% compared with the first quarter of ... Operating profit totaled SEK 589.1 M (loss: 18.8) and the operating ... SEK 7.12 (loss: 0.32) Cash flow from operations was ... , The 2016 revenue guidance is unchanged, SEK 7,000-8,500 M. ...
(Date:4/15/2016)... 2016  A new partnership announced today will ... decisions in a fraction of the time it ... high-value life insurance policies to consumers without requiring ... Force Diagnostics, rapid testing (A1C, Cotinine and HIV) ... pressure, weight, pulse, BMI, and activity data) available ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... , ... Supplyframe, the Industry Network for electronics hardware design ... Located in Pasadena, Calif., the Design Lab’s mission is to bring together inventors ... and brought to market. , The Design Lab is Supplyframe’s physical representation of ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
(Date:6/23/2016)... 23, 2016 On Wednesday, June 22, ... down 0.22%; the Dow Jones Industrial Average edged 0.27% lower ... 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on the following ... Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ... BIND ). Learn more about these stocks by accessing ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... of intelligent tools designed, tuned and optimized exclusively for Okuma CNC machining centers ... The result of a collaboration among several companies with expertise in toolholding, cutting ...
Breaking Biology Technology: