Navigation Links
Hidden strains of HPV found in 'virus-negative' genital warts
Date:7/11/2013

There are 170 established HPV types. Cancerous human papillomavirus (HPV) viruses are the main cause of cervical cancer, and are found in close to 100% of cervical tumors.

Cervical cancer and genital warts are caused by HPV. However, testing for the virus using standard techniques can sometimes give a negative result -- in these cases, the condylomas are called 'virus-negative' warts.

In a new study published in Virology, researchers assessed the DNA found in samples taken from 40 patients with 'virus-negative' genital warts. Through a general DNA sequencing approach, the researchers showed that several of the negative samples did in fact contain HPV DNA.

This means that virus-negative warts can harbor small amounts of more distantly related viruses that escaped previous detection. According to the research, there is a diverse pool of previously unknown HPV types that infect humans and are detectable on genital warts.

The findings have implications for the knowledge of diversity of HPV types, as these viruses are currently undetectable using traditional testing methods.

Ten pools of four samples taken from virus-negative warts were tested using genetic material straight from the patient -- including viral, bacterial and human DNA. Five of the pools contained HPV, and three of these contained new strains of the virus.

Altogether, 1337 pieces of HPV-related DNA were detected, representing 23 new types of HPV, 10 established types of HPV and two known HPV DNA sequences.

This new style of testing has highlighted previously unknown forms of the virus. As such, we learn more about the evolution of different HPV types. It is possible that the previously unknown forms of the virus do not cause condyloma but may be secondary invaders of condyloma.


'/>"/>

Contact: Sacha Boucherie
s.boucherie@elsevier.com
31-204-853-564
Elsevier
Source:Eurekalert

Page: 1

Related biology news :

1. Hidden effects of climate change may threaten eelgrass meadows
2. Hidden layer of genome unveils how plants may adapt to environments throughout the world
3. Microbiologists eavesdrop on the hidden lives of microbes
4. Immune system molecule with hidden talents
5. MBL scientists to explore hidden realm of microbes, viruses beneath the ocean floor
6. Hidden secrets in the worlds most northerly rainforests
7. Blowing in the wind: How hidden flower features are crucial for bees
8. Elephant seal tracking reveals hidden lives of deep-diving animals
9. First satellite tag study for manta rays reveals habits and hidden journeys of ocean giants
10. Researchers create method to rapidly identify specific strains of illness
11. Researchers develop a faster method to identify Salmonella strains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... BEACH GARDENS, Fla. , April 11, 2017 ... identity management and secure authentication solutions, today announced ... contract by Intelligence Advanced Research Projects Activity (IARPA) ... for IARPA,s Thor program. "Innovation has ... onset and IARPA,s Thor program will allow us ...
(Date:4/5/2017)...  The Allen Institute for Cell Science today announces ... portal and dynamic digital window into the human cell. ... application of deep learning to create predictive models of ... a growing suite of powerful tools. The Allen Cell ... publicly available resources created and shared by the Allen ...
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, Sequencing.com ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... The ... three Winners and six Finalists of the 2017 Blavatnik Regional Awards for Young ... Family Foundation and administered by the New York Academy of Sciences to honor ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... States multicenter, prospective clinical study that demonstrates the accuracy of the FebriDx® ... identifying clinically significant acute bacterial and viral respiratory tract infections by testing ...
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a global contract research, ... improve patient outcomes and quality of life, will now be offering its impurity ... to new regulatory requirements for all new drug products, including the finalization of ...
(Date:10/11/2017)... ... October 11, 2017 , ... At its national ... Dr. Suneel I. Sheikh, the co-founder, CEO and chief research scientist of Minnesota-based ... selected for membership in ARCS Alumni Hall of Fame . ASTER Labs ...
Breaking Biology Technology: