Navigation Links
Helping the brain's messengers get from A to B
Date:6/10/2010

ndividual proteins can be directly visualized in nearly real time.

"Understanding molecular movements is important because enzyme functions hinge on motion," says Dr. Blanchard, another senior author of the new study. "To observe molecules, we attach reporter molecules called fluorophores that can be directly measured at the single-molecule scale. In so doing, motional information can be obtained about the protein to which they are linked."

In the current study, the investigators used this technique to study the LeuT transporter. They were able to monitor changes of individual molecules and reported observing two distinct states which they believe report on the open and closed states of the gating mechanism.

Dr. Weinstein notes that SSRIs were developed without a real understanding of how they work and only now researchers are beginning to understand how they bind and affect the transporters. "These medications are effective in treating many mental illnesses, including depression, obsessive-compulsive disorder and panic disorder, suggesting that these disorders have some relation to serotonin levels in the brain. Our study is the start of understanding how SSRIs work at a mechanistic level, and why they work in some people and not in others."


'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New psychological intervention program shows promise in helping those with bowel diseases
2. Helping hearts, spinal cords and tendons heal themselves
3. Helping the NRC look below the surface
4. New insights into helping marine species cope with climate change
5. Texas AgriLife researchers helping
6. Tennessee foresters helping to return chestnuts to American forests
7. Energy experts helping Australian households reduce carbon emissions
8. Green IT not helping climate change
9. Satellites helping aid workers in Honduras
10. Researcher helping to pioneer medical therapy for Fragile X Syndrome presents latest findings
11. Giving nature a helping hand
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/29/2014)... have been blamed for increasing the risk of ... family history of schizophrenia, are widely accepted. Others, ... a parasite transmitted by soil, undercooked meat and ... A new study by Gary Smith, professor of ... Pennsylvania,s School of Veterinary Medicine, used epidemiological modeling ...
(Date:10/29/2014)... number of chemicals from household and industrial products are ... bodies. But for most of them, scientists have yet ... taken the first step toward doing that by estimating ... new method is published in the ACS journal ... and colleagues note that the risks to human health ...
(Date:10/29/2014)... on September 19, 2014, leading geneticist and humanitarian Prof. ... Sciences and Medicine at the University of Washington in ... Aviv University, was awarded the 2014 Lasker-Koshland Special Achievement ... honorary degree from TAU, Prof. King was the 2012-2013 ... for the past 18 years she has been the ...
Breaking Biology News(10 mins):Penn vet professor investigates parasite-schizophrenia connection 2Penn vet professor investigates parasite-schizophrenia connection 3Geneticist and humanitarian: Prof. Mary-Claire King receives Lasker Award 2
... The Aplastic Anemia & MDS International Foundation (AA&MDSIF) is ... Drug Administration (FDA) has expanded the label for VIDAZA ... found that Vidaza is the only agent that extends ... shown to delay progression to acute myelogenous leukemia (AML) ...
... with gold purify the air when they are lit ... Technology experts have discovered. Associate Professor Zhu Huai ... said that glaziers in medieval forges were the first ... sizes. Professor Zhu said numerous church windows ...
... MobileSRO(TM) and MobileCampus(TM) Wireless Data Communications Link School ... Security, Administration ... International,Inc. (OTC Bulletin Board: BKYI), a leader in finger-based ... of MobileSRO(TM) and MobileCampus(TM), silent, secure,emergency alert and management ...
Cached Biology News:Air-purifying church windows early nanotechnology 2BIO-key(R) Announces Emergency Alert and Management Solutions for Schools and Campuses 2BIO-key(R) Announces Emergency Alert and Management Solutions for Schools and Campuses 3
(Date:10/30/2014)... Ras Al Khaimah, UAE (PRWEB) October 30, 2014 ... the appointment of Dr. James A. Manganello, Chairman of the ... (NSCEC) of The Bahamas. The appointment was made by ... The Bahamas on September 24th, 2014. , More ... Cell Therapy and Research Bill , Prime Minister Perry Christie ...
(Date:10/30/2014)... in the development of quantum technologies has been proposed ... published today (28 October) in Nature Communications , ... a new type of flexibly designed microscopic trap for ... and specialised superfast computers, often depend on harnessing the ... these tiny particles are hugely problematic because of the ...
(Date:10/27/2014)... 27, 2014 The Italian ... exhibit and sell its artificial "lower limb", after ... patent.      (Photo: http://photos.prnewswire.com/prnh/20141027/713097 ... fighting, the definitive judgement has arrived: Roadrunnerfoot, the ... and accessible hi-tech prostheses with composite materials, has ...
(Date:10/27/2014)... MA (PRWEB) October 27, 2014 ... profit. SoundConnect , an industry leading unified ... its partners and agents to deliver cloud-based audio ... accelerate growth opportunities. , With SoundConnect’s Q4 ... every twenty-five video and/or web conferencing licenses sold, ...
Breaking Biology Technology:Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3Italian Lower Limb Prosthesis Company Wins Lawsuit Against German Giant Ottobock 2SoundConnect Unveils Q4 Partner Incentives 2
... resources to empower transplant patients ... ... Pharma US,Inc. (Pink Sheets: ALPMF), a leader in the field ... transplant,professional organization, announced a collaborative partnership to jointly,develop further materials ...
... Pharmaceuticals,Inc. announced today that BC Detect(SM), the ... available from Panacea Laboratories. BC,Detect(SM) is a ... identification,of recurrence among women successfully treated for ... Pharmaceuticals, is certified under the,Clinical Laboratory Improvement ...
... of anti-infectives, to ... on pexiganan development, WELLESLEY HILLS, Mass., Oct. 17 ... of rights to pexiganan, Michael Zasloff, M.D. has joined the,company,s ... the African clawed frog while at NIH (National Institutes of,Health) ...
Cached Biology Technology:Astellas Pharma US, Inc. and The International Transplant Nurses Society (ITNS) Collaborate on Content for Transplant Experience Program 2Astellas Pharma US, Inc. and The International Transplant Nurses Society (ITNS) Collaborate on Content for Transplant Experience Program 3Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer 2Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer 3Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer 4MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 2MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 3MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 4MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 5
ANTI-HUMAN CYTOKINES, GROWTH FACTORS (polyclonal rabbit (or goat) antibodies) Human TARC - Biotin...
Mouse monoclonal [7C6] to Bcr-abl ( Abpromise for all tested applications). SwissProtID: P11274...
Rabbit polyclonal to Glutathione S Transferase alpha ( Abpromise for all tested applications). Antigen: Full length protein: Human Glutathione S Transferase alpha. Entrez GeneID: 2938 Swi...
Chicken polyclonal to Thioredoxin domain containing 9 ( Abpromise for all tested applications). Antigen: Full length protein (Human) Entrez Gene ID: 10190 Swiss Protein ID: O14530...
Biology Products: