Navigation Links
'Healthy' sterols may pose health risk
Date:7/14/2008

Plant sterols have been touted as an effective way to lower cholesterol and reduce the risk of heart disease. However, a research study in the July JLR has uncovered that these compounds do have their own risks, as they can accumulate in heart valves and lead to stenosis.

Aortic valve stenosis (AS) results from cholesterol accumulation in the valve between the left ventricle and aorta; this impedes the flow of blood and puts extra pressure on the heart. About 2% of individuals over 65 (and over 5% of those over 85) have AS, and as the population ages, it is becoming an increasing problem.

Plant sterols can block the absorption of dietary cholesterol into the body, and as such high vegetable diets and/or plant sterol supplements are often used to alleviate high cholesterol. However, although plant sterols themselves are poorly absorbed, they can enter the body, so Satu Helske and colleagues examined whether plant sterols can also accumulate in aortic valves.

They collected blood samples from 82 patients with severe AS and aortic valves from 21 individuals undergoing valve surgery, along with respective controls. They observed that non-cholesterol sterols, including plant sterols, can accumulate in aortic valves, and at levels that directly related to their blood concentration.

These findings suggest that beneficial plant sterols may end up becoming a risk factor for AS, although the researchers will need to conduct more studies, such as whether dietary sterols and sterol supplements produce different effects.


'/>"/>

Contact: Nick Zagorski
nzagorski@asbmb.org
301-634-7366
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

Page: 1

Related biology news :

1. Healthy or diseased?
2. Caloric intake negatively influences healthy adults sleep patterns
3. Fat intake negatively influences the sleep pattern in healthy adults
4. Study finds healthy intestinal bacteria within chicken eggs
5. Healthy parents provide clues to survival of young haddock on Georges Bank
6. Crop management strategies key to a healthy Gulf, planet
7. Macadamia nuts can be included in heart healthy diet
8. U of M research finds teens who have TV in their bedroom are less likely to engage in healthy habits
9. Healthy rivers needed to remove nitrogen
10. Iowa Staters talk biofuels, healthy oils and pharma crops at AAAS meeting
11. Want healthy gums? Hit the dairy aisle
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/1/2017)...  Aware, Inc. (NASDAQ: AWRE), a leading supplier of ... Moberg has resigned, effective March 3, 2017, as ... and Treasurer of Aware citing a desire to retire.  ... of the Board of Directors of Aware. ... and co-President, General Counsel has been named Chief Executive ...
(Date:2/26/2017)... Feb. 25, 2017  Securus Technologies, a leading ... for public safety, investigation, corrections and monitoring, announces ... Reentry. "Too often, too many offenders ... county jails are trying to tackle this ongoing ... friends and family members. While significant steps are underway, ...
(Date:2/16/2017)... Feb. 16, 2017  Genos, a community for ... it has received Laboratory Accreditation from the College ... presented to laboratories that meet stringent requirements around ... rigorous processes. "Genos is committed to ... practices. We,re honored to be receiving CAP accreditation," ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... New York , March 23, 2017 ... blood plasma products and derivatives market is fragmented due to the presence ... players, such as Proliant, Thermo Fisher , and Sigma-Aldrich, compete ... leader, these three companies, collectively, held more than 76% of this ... ...
(Date:3/22/2017)... ... March 22, 2017 , ... Researchers face a fundamental ... samples to full-size tissues, bones, even whole organs to implant in people to ... blood deep into the developing tissue. , Current bioengineering techniques, including 3-D ...
(Date:3/22/2017)... 2017   iSpecimen ®, the marketplace ... Pathology Service (DPS), a full-service anatomic pathology reference ... United States , has joined a program offered ... (DHIN) to make human biospecimens and associated data ... program, announced in 2015 as a collaboration between iSpecimen ...
(Date:3/22/2017)... 22, 2017   VWR (NASDAQ: ... product and service solutions to laboratory and ... acquired EPL Archives, Inc., an international biorepository ... entire regulated product research, development and commercialization ... and ancillary services. EPL Archives is widely ...
Breaking Biology Technology: