Navigation Links
Head and neck cancer survivors who use alcohol and cigarettes have increased death risk
Date:12/2/2009

PHILADELPHIA Cigarette smoking and alcohol consumption before head and neck cancer diagnosis strongly predicts the patient's future risk of death, according to published studies. Now, results of a new study show a similar effect among those who continued these habits after cancer diagnosis.

"Most cancer survivors are counseled to quit smoking; despite this, many still smoke. In our study, 21 percent continued to smoke even after their cancer diagnosis, increasing their risk of death," said researcher Susan T. Mayne, Ph.D. "Similarly, we found that continued drinking increases the risk of death."

Based on these findings, Mayne advises survivors of head and neck cancer which includes cancers of the oral cavity, pharynx and larynx to quit smoking cigarettes and drinking alcoholic beverages in order to increase their odds of longer survival. Mayne is a professor of epidemiology at the Yale Schools of Public Health and Medicine, and the associate director of the Yale Comprehensive Cancer Center.

Results of this study are published in the December issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. This issue has a special focus on tobacco.

Mayne and colleagues evaluated the habits of 264 recent survivors of early stage head and neck cancer before and after cancer diagnosis. They obtained detailed smoking and drinking histories through in-person and telephone interviews. Patient recruitment was conducted at 49 hospitals in Connecticut and Florida. The purpose of this study was to evaluate if these habits affected the risk of dying in subsequent years.

After more than four years of follow-up, 62 patients died.

Patients who continued to smoke were approximately two times as likely to die during the follow-up, as compared to those who did not smoke after diagnosis. Patients who continued to drink after diagnosis were approximately three times as likely to die during the follow-up, according to Mayne.

"We expected to see an adverse effect of continued smoking; I was really not sure what we would find for continued drinking," she said. "The data from our study indicated that continued drinking should be discouraged in head and neck cancer survivors. Patients need assistance with both tobacco and alcohol cessation."

Yale researchers are conducting studies to determine the most effective ways to help head and neck cancer survivors stop smoking. One preliminary study will compare medications to help survivors quit, and will specifically focus on the effectiveness of varenicline (Chantix) compared with the nicotine patch. Some evidence has shown that varenicline may also help reduce alcohol consumption in patients. Given these findings, the researchers will monitor alcohol use and address potential methods to help patients quit.

This research, published in Cancer Epidemiology, Biomarkers & Prevention, was conducted as a partnership between the Yale Comprehensive Cancer Center and the University of Miami/Sylvester Comprehensive Cancer Center. The National Cancer Institute funded the study.


'/>"/>

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert  

Related biology news :

1. Exposure to secondhand cigarette smoke over a lifetime increased breast cancer risk later in life
2. Repeat negative CT scan for lung cancer does not encourage ex-smokers to resume the habit
3. Combining nanotubes and antibodies for breast cancer search and destroy missions
4. Racial disparity in colon cancer survival not easily explained, UAB researchers say
5. Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
6. Kill the cancer, not the patient: New toxicity testing approach could make chemo drugs safer
7. Cancers sweet tooth may be weakness
8. FDA approved leukemia drugs shows promise in ovarian cancer cells
9. For young boys with cancer, testicular tissue banking may be option to preserve fertility
10. AACR, NCI and EORTC to host Molecular Targets and Cancer Therapeutics International Conference
11. New synthetic molecules trigger immune response to HIV and prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Head and neck cancer survivors who use alcohol and cigarettes have increased death risk
(Date:2/2/2017)... -- Central to its deep commitment to honor the ... Prize Foundation today announced the laureates of the ... in their respective fields of Life Sciences and ... recognized with the 2017 Japan Prize for original ... the advancement of science and technology, but also ...
(Date:1/26/2017)... DENVER , Jan. 26, 2017  Acuity ... Trends for Biometrics and Digital Identity".  Acuity characterizes ... digital identity when increased adoption reflects a new ... "Biometrics and digital identity are ... says Maxine Most , Principal of Acuity ...
(Date:1/21/2017)... , Jan 20, 2017 Research and ... Biometrics Market 2017-2021" report to their offering. ... The global voice recognition biometrics ... 2017-2021. The report covers the present scenario and ... 2017-2021. To calculate the market size, the report considers the revenue ...
Breaking Biology News(10 mins):
(Date:2/23/2017)... , Feb. 23, 2017  MIODx announced ... for two key immunotherapy technologies from the University ... provides a method to monitor a patient for ... PD-L1 and CTLA-4.  The second license extends the ... patient is likely to have an immune-related adverse ...
(Date:2/23/2017)... ... 23, 2017 , ... Brain Sentinel, Inc. has received US ... System, the Brain Sentinel® Seizure Monitoring and Alerting System. The adjunctive seizure monitoring ... of rest. A lightweight, non-invasive monitor is placed on the belly of the ...
(Date:2/23/2017)... ... February 23, 2017 , ... The Greater Gift Initiative, ... partnership with Compass Research . GGI's mission is to advance global health and ... child in need in honor of each clinical trial volunteer. The vision of GGI ...
(Date:2/23/2017)... , ... February 22, 2017 , ... ... photonics , have been named Fellows of the Society this year, the Fellows ... in the multidisciplinary fields of optics, photonics, and imaging as well as their ...
Breaking Biology Technology: