Navigation Links
Having first-degree relative with atrial fibrillation linked with increased risk
Date:11/13/2010

An examination of the heritability of atrial fibrillation (AF) among more than 4,000 participants in the Framingham Heart Study finds the occurrence of AF in first-degree relatives was associated with AF risk after adjustment for established AF risk factors and AF-related genetic variants, according to a study that will appear in the November 24 issue of JAMA. The study is being released early online because it will be presented at the American Heart Association's annual meeting.

"A heritable component underlying atrial fibrillation has been well demonstrated, and it is now evident that genetic variants are associated with AF risk," the investigators write. However, the contribution of familial AF (defined in this study as the occurrence of AF in a first-degree relative prior to an examination commencing an 8-year follow-up period) to predicting new-onset AF remains unknown.

Steven A. Lubitz, M.D., M.P.H., of the Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Mass., and colleagues examined the association between AF occurrence in a first-degree relative and AF risk and hypothesized that considering familial AF would improve prediction of new-onset AF. Participants were from the Framingham Heart Study, a prospective community-based cohort study started in 1948. Original and offspring participants were at least 30 years of age, free of AF at the beginning of the study, and had at least 1 parent or sibling enrolled in the study. The 4,421 participants in this analysis (average age, 54 years; 54 percent women) were followed up through December 2007.

During the period 1968-2007, 440 participants developed AF. Familial AF occurred among 1,185 participants (26.8 percent) and premature familial AF (onset 65 years of age or younger) occurred among 351 participants (7.9 percent). Of the 2,393 baseline examinations at which familial AF was present, sources included fathers (n = 1,163), mothers (n = 1,068), and
'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8491
JAMA and Archives Journals
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Women with diabetes having more C-sections and fetal complications: study
2. Caltech researchers obtain first brain recordings from behaving fruit flies
3. Womens soccer -- get fit while having fun
4. Immigrant women may be at higher risk of having a baby with a birth defect
5. Gaining too much weight during pregnancy nearly doubles risk of having a heavy baby
6. UF to help sequence genome of flowering plants ancient living relative
7. Gulf oil dispersants unlikely to be endocrine disruptors and have relatively low cell toxicity
8. New book reviews research on p53 -- the guardian of the genome -- and its relatives
9. UF researchers: Ancient crocodile relative likely food source for Titanoboa
10. Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
11. Gene decides whether coral relative will fuse or fight
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2013)... 18, 2013) Research presented today at Digestive Disease ... with findings about the impact of coffee on autoimmune ... While coffee consumption recently has been associated with reduced ... a few more cups of java each month also ... disease. Researchers at the Mayo Clinic, Rochester, MN, linked ...
(Date:5/18/2013)... An increasing number of U.S. children are ... according to research presented at Digestive Disease Week ... researchers at the Cleveland Clinic Children,s Hospital found ... exhaled breath compared to their lean counterparts. The ... that can be correlated to potential complications associated ...
(Date:5/17/2013)... provide the white noise of the South, but the night ... Southern air hangs heavy from the humidity and the sounds ... 140 species of frogs, toads and salamanders, is the center ... and swamps are the auditorium for their symphonic choruses, the ... Initiative, or ARMI, have front-row seats. , Amphibians, ...
Breaking Biology News(10 mins):Coffee consumption associated with reduced risk of autoimmune liver disease 2New research identifies risks, interventions for children's GI health 2New research identifies risks, interventions for children's GI health 3Front-row seats to climate change 2Front-row seats to climate change 3Front-row seats to climate change 4
... to improve water use in agriculture now will we meet ... years. "With earth's water, land and human resources it ... it is probable that today's food production and environmental trends ... says David Molden Deputy Director General of the International Water ...
... after its introduction, gene therapy still holds great promise as ... as human immunodeficiency syndrome (HIV). But scientists have yet to ... is capable of delivering therapeutic payloads to specific cells. ... the USC Viterbi School of Engineering may be turning a ...
... of a new technique that reads the makeup of ... by adding phosphate to proteins manufactured in human cells. ... of these so-called phosphorylation events to lists compiled by ... Web - PhosphoMotif Finder [ http://www.hprd.org/PhosphoMotif_finder ] ...
Cached Biology News:Living with water scarcity -- world must act now 2Living with water scarcity -- world must act now 3Living with water scarcity -- world must act now 4Living with water scarcity -- world must act now 5Can engineered immune cells stop AIDS? 2Can engineered immune cells stop AIDS? 3Speeding 'fingertip' discovery -- 20 years of protein info in 1 place 2
(Date:5/17/2013)... Topricin Pain Relief and Healing ... listed among nationally recommended over-the-counter (OTC) health products ... "U.S. News" Health in collaboration with "Pharmacy Times." ... 1 Pharmacists Recommended designation” in the “Topical Analgesics” ... and is the only homeopathic formula to earn ...
(Date:5/17/2013)... 17, 2013 Oven Industries Inc. announces ... 5R6-900 temperature controller has many user-friendly benefits. Contained all ... the wall as a self-contained temperature control ... detail makes the device unique, as well as highly ... also be used universally, which allows the user to ...
(Date:5/17/2013)... Photographers know the ... see which branch a bird is sitting on, but spotting ... lens for high-magnification images requires considerable skill. It is a ... the active biomolecules of cells. , Olga Schubert, a doctoral ... her colleagues have now come up with a search aid. ...
(Date:5/17/2013)... Cardiff, UK (PRWEB) May 17, 2013 ... by Photonics21 at the association’s recent annual ... others including EC Vice-President Neelie Kroes, who called the ... between sectors, and a stimulant to European innovation.” , ... the structure of the new Photonics PPP at its ...
Breaking Biology Technology:Pharmacists' Picks: Topical BioMedics' Topricin Listed on Top Recommended OTC Health Products 2New Temperature Control Products Announced by Oven Industries Inc. 2Proteome atlas for the tuberculosis pathogen 2Proteome atlas for the tuberculosis pathogen 3SPIE Joins in Praise for ‘Huge Step Forward’ for Innovation R&D Enabled by Photonics21 Actions 2SPIE Joins in Praise for ‘Huge Step Forward’ for Innovation R&D Enabled by Photonics21 Actions 3
... up" when they're near a reader and can ... including its history, quantity, location and condition. ... major companies are scurrying to develop strategies for ... mandates from Wal Mart and the U.S. Department ...
... his February 14, 2005 article, Michael Rosen argues ... and suggests that this will be a good thing. ... for traditional pharmaceuticals. This strategy has not been particularly ... be well-served if Big Pharma adopts this same strategy ...
... in its March edition a list of leading technology ... the environment for formation and development of nanotechnology and ... devices and diagnostics. , ,Before I provide you with ... they used to compute their ranking. They looked at ...
Cached Biology Technology:UW-Madison workgroup helps state companies tap the power of RFID 2UW-Madison workgroup helps state companies tap the power of RFID 3UW-Madison workgroup helps state companies tap the power of RFID 4Big Pharma already has a generic strategy, but needs new direction 2Big Pharma already has a generic strategy, but needs new direction 3Midwest states in top 10 small-tech hotspots 2
... Microdissection , CapSure HS and CapSure Macro ... extraction of populations of pure cells from ... Capture Microdissection., Ensure the Integrity of ... All CapSure LCM Caps have a patented ...
... system is used for single-color real-time detection ... or JOE fluorophores and features a real-time ... data from 96 wells, a gene expression ... analysis. The system includes the optical module ...
... Microdissection , CapSure HS and CapSure Macro ... extraction of populations of pure cells from ... Capture Microdissection., Ensure the Integrity of ... All CapSure LCM Caps have a patented ...
Opticon continuous fluorescence detector; includes optical base, analysis software, computer and monitor (this is an accessory for the DNA Engine thermal cyclers which must be ordered seperately)...
Biology Products: