Navigation Links
Harmful effects of hypothyroidism on maternal and fetal health drive new guidelines for managing thyroid disease in pregnancy
Date:7/25/2011

New Rochelle, NY, July 25, 2011 Emerging data clarifying the risks of insufficient thyroid activity during pregnancy on the health of the mother and fetus, and on the future intellectual development of the child, have led to new clinical guidelines for diagnosing and managing thyroid disease during this critical period. The guidelines, developed by an American Thyroid Association (ATA) expert task force, are presented in Thyroid, a peer-reviewed journal published by Mary Ann Liebert, Inc. and are available free online at www.liebertpub.com/thy

Clinical studies are producing critical data demonstrating the harmful effects not only of overt hypothyroidism and hyperthyroidism on pregnancy, but also of subclinical thyroid disease and maternal and fetal health. Ongoing research is clarifying the link between miscarriage and preterm delivery in women with normal thyroid function who are thyroid peroxidase antibody positive. Studies are also uncovering the long-term effects of postpartum thyroiditis.

"Pregnancy has a profound impact on the thyroid gland and thyroid function. In essence, pregnancy is a stress test for the thyroid, resulting in hypothyroidism in women with limited thyroidal reserve or iodine deficiency," state Alex Stagnaro-Green, George Washington University School of Medicine and Health Sciences (Washington, DC), and coauthors representing the ATA task force.

Among the many specific recommendations detailed in the guidelines are the following: women with overt hypothyroidism or with subclinical hypothyroidism who are TPO antibody positive should be treated with oral levothyroxine; use of other thyroid preparations such as triiodothyronine or desiccated thyroid to treat maternal hypothyroidism is strongly recommended against; and women with subclinical hypothyroidism in pregnancy who are not initially treated should be monitored for progression to overt hypothyroidism with serum TSH and free T4 measurements about every 4 weeks until 16-20 weeks gestation and at least once between 26-32 weeks gestation.

The new clinical guidelines focus on several key areas in the diagnosis and management of thyroid disease during pregnancy and postpartum: thyroid function tests, hypothyroidism, thyrotoxicosis, iodine, thyroid antibodies and miscarriage/preterm delivery, thyroid nodules and cancer, postpartum thyroiditis, recommendations on screening for thyroid disease during pregnancy, and areas for future research.

"These important guidelines were developed by a panel of international experts representing the disciplines of endocrinology, obstetrics and gynecology, and nurse midwives. This broad representation of providers that care for pregnant women will significantly increase the impact of these guidelines and translation of findings from the most recent research to clinical practice," says Gregory A. Brent, MD, Professor of Medicine and Physiology, David Geffen School of Medicine at the University of California Los Angeles and President of the ATA.

"Thyroid disease in pregnancy is common, clinically important, and time-sensitive, and our knowledge about it is rapidly changing. This ATA Guideline will disseminate this new information both widely and rapidly to improve patient care, establish what we believe is optimal care for the pregnant woman and her unborn child, and drive future research to further improve our understanding and patient outcomes," says Richard T. Kloos, MD, Professor, The Ohio State University and Secretary/Chief Operating Officer of the ATA.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related biology news :

1. Plan to one day end the use of environmentally harmful chemicals on commercial crops developed
2. Oceans harmful low-oxygen zones growing, are sensitive to small changes in climate
3. Overweight more harmful to the liver than alcohol in middle-aged men
4. Baylor study finds common fire retardant harmful to aquatic life
5. Mutant prions help cells foil harmful protein misfolding
6. UT researchers crack code to harmful brown tides
7. First harmful algal bloom species genome sequenced
8. UT researchers link algae to harmful estrogen-like compound in water
9. Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy
10. Cinnamon can replace harmful chemicals used to create nanoparticles
11. Harm reduction cigarettes can be more harmful than conventional brands, researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Harmful effects of hypothyroidism on maternal and fetal health drive new guidelines for managing thyroid disease in pregnancy
(Date:5/6/2017)... SINGAPORE , May 5, 2017 ... has just announced a new breakthrough in biometric ... that exploits quantum mechanical properties to perform ... new smart semiconductor material created by Ram Group ... across finance, entertainment, transportation, supply chains and security. ...
(Date:4/17/2017)... Florida , April 17, 2017 NXT-ID, ... technology company, announces the filing of its 2016 Annual Report on ... and Exchange Commission. ... on Form 10-K is available in the Investor Relations section of ... as on the SEC,s website at http://www.sec.gov . ...
(Date:4/11/2017)... 2017 Research and Markets has announced the ... to their offering. ... eye tracking market to grow at a CAGR of 30.37% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... 15, 2017 , ... JULABO USA introduces its new website ... makes it easy to navigate through the site whether you’re in the office, ... information, educational industry content and visit the company’s social media accounts, all on ...
(Date:8/11/2017)... ROCKVILLE, Md. , Aug. 11, 2017 ... in a New York Times article regarding ... 9.2 billion, according to Kalorama Information.  The ... an App for That"  used information ... Remote Patient Monitoring & Telemedicine Market  (Sleep, ...
(Date:8/10/2017)... ... August 09, 2017 , ... As a full-service marketing ... ideal customers with the right message. Their effective, cutting-edge inbound marketing strategies are ... realize how crucial the agriculture industry is,” said David Phelps, chief marketing officer ...
(Date:8/10/2017)... , ... August 09, 2017 , ... Okyanos Center for ... place at the Pelican Bay Hotel in Freeport, Grand Bahama on September 27, 2017. ... required. , With oversight from the Ministry of Health’s National Stem Cell Ethics ...
Breaking Biology Technology: