Navigation Links
Happy Father's Day! Another reason why dads and hopeful dads should quit smoking now
Date:6/22/2012

Bethesda, MDAs you decide what to get dad for Father's Day, you might want to consider what he gave you when you were conceived. If he smoked, your genes are likely damaged, and your odds for cancers and other diseases throughout your life could be increased. A new research report appearing online in the FASEB Journal, scientists show for the first time in humans that men who smoke before conception can damage the genetic information of their offspring. These inherited changes in DNA could possibly render an offspring in the womb susceptible to later disease such as cancer. This provides evidence showing why men should be urged to stop smoking before trying to conceive in the same way women have been urged to quit. Interestingly, a fertile sperm cell takes about three months to fully develop; therefore men would ultimately need to quit smoking long before conception to avoid causing genetic problems.

"That smoking of fathers at the time around conception can lead to genetic changes in their children indicates that the deleterious effects of smoking can be transmitted through the father to the offspring," said Diana Anderson, Ph.D., a researcher involved in the work from the School of Life Sciences at the University of Bradford, in the United Kingdom. "These transmitted genetic changes may raise the risk of developing cancer in childhood, particularly leukemia and other genetic diseases. We hope that this knowledge will urge men to cease smoking before trying to conceive."

To make this discovery, Anderson and colleagues used DNA biomarkers to measure genetic changes in the paternal blood and semen around conception, as well as maternal and umbilical cord blood at delivery in families from two different European regions in central England and a Greek island. Information regarding the lifestyle, environmental and occupational exposures of these families was taken from validated questionnaires. The combined analysis of exposures and DNA biomarkers was used to evaluate the role of exposures before conception and during pregnancy in the causation of genetic changes in the offspring. These results have strong implications for the prevention of disease.

"This report shows that smoking is a germ cell mutagen. If dad uses cigarettes, his kids will be affected even before they are born," said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal. "As Father's Day approaches, family members may want to give dads and prospective dads the help they need to quit smoking for good."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. First paternity study of southern right whales finds local fathers most successful
2. Nanotherapy: Treating deadly brain tumors by delivering big radiation with tiny tools
3. Countries should implement inclusive wealth accounting
4. President, CEO Leppävuori, VTT: Finland should create a national bioeconomy strategy
5. Reproductive health providers should discuss environmental exposure risks with patients
6. Should we play hide-and-go-seek with our childrens vegetables?
7. Scripps Florida scientists awarded $8.4 million grant to develop new anti-smoking treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/3/2017)... 2017  Data captured by IsoCode, IsoPlexis ... a statistically significant association between the potency ... and objective response of cancer patients post-treatment. ... whether cancer patients will respond to CAR-T ... as to improve both pre-infusion potency testing and ...
(Date:3/30/2017)... The research team of The Hong Kong ... identification by adopting ground breaking 3D fingerprint minutiae recovery and matching ... and accuracy for use in identification, crime investigation, immigration control, security ... ... A research team led by ...
(Date:3/29/2017)... 29, 2017  higi, the health IT company that ... North America , today announced a Series B ... of EveryMove. The new investment and acquisition accelerates higi,s ... to transform population health activities through the collection and ... higi collects and secures data today on behalf ...
Breaking Biology News(10 mins):
(Date:8/21/2017)... (PRWEB) , ... August 21, 2017 , ... ... for two speakers for this two-part educational webinar, in which attendees will learn ... and associated protein factor composition. Along with an overview of the development and ...
(Date:8/18/2017)... Jose, CA (PRWEB) , ... August 18, 2017 ... ... advanced precision Lithography Equipment for the Semiconductor, MEMS, and Microfluidics Industries, announces the ... features and specifications found more often in automated production mask aligners. OAI has ...
(Date:8/16/2017)... ... August 16, 2017 , ... Tunnell Consulting announced today ... the ISPE Annual Meeting and Expo , to be held October 29 through ... theme is “Driving innovation to advance patient therapies.” , The ISPE Annual Meeting and ...
(Date:8/16/2017)... ... August 16, 2017 , ... While art and science ... more closely connected than one might think. A Mesh Is Also a Snare, ... the University City Science Center’s Esther Klein Gallery (EKG) on August 17 and run ...
Breaking Biology Technology: