Navigation Links
Half of Tamiflu prescriptions went unused during 2009 H1N1 swine flu pandemic, UK sewage study
Date:4/17/2013

y diverting limited antiviral stocks from those who may need it most. Mis-used antivirals can lead to antiviral resistance and represents a significant financial cost and health risk. Previous research on antiviral compliance had focused on small populations, typically fewer than 200, and used survey-based analyses of drug compliance, which can be unreliable.

Dr Singer adds, "Our study was the first compliance study to utilise waste water as an evidence base for whether a population consumed Tamiflu or not. Because of this unique study design, we were able to examine populations orders of magnitude larger than previous studies. One population was just over 6,000 people and the second population was 208,000. Tamiflu gets transformed into the active antiviral only after being consumed, and is released into the sewage with every visit to the toilet. This waste water epidemiology approach is particularly robust for drugs such as Tamiflu and potentially more reliable than some survey based methods of assessing compliance."

Predictions of oseltamivir consumption from Tamiflu recovered in sewage were compared with two sources of national government statistics to derive compliance rates. Scenario and sensitivity analysis indicated an estimated compliance rate between 45-60%, (between 45 to 60 people out of every 100 people who received Tamiflu completed the antiviral course, as prescribed).

Dr Singer says, "With approximately half the collected antivirals going unused, there is a clear need to improve public health messages so that less antiviral is wasted and that the duration and severity of infection is reduced. Furthermore, we feel the waste water epidemiology approach undertaken can potentially help shape future public health messages, making them more timely, targeted, and population sensitive, while potentially leading to less mis- and un-used antiviral, less wastage and ultimately a more robust and efficacious pandemic preparedness st
'/>"/>

Contact: Barnaby Smith
bpgs@ceh.ac.uk
44-079-202-95384
Centre for Ecology & Hydrology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. 3 distinguished keynote speakers to present during ARVO 2013 Annual Meeting
2. Preventing obesity transmission during pregnancy
3. Female deer take control during the mating season
4. Abuse during childhood linked to uterine fibroids in African-American women
5. Choline supplementation during pregnancy presents a new approach to schizophrenia prevention
6. Chromosome anchors organize DNA during cell division
7. Music with dinner: Whales sing during foraging season, not just while breeding
8. Abuse during childhood linked to adult-onset asthma in African-American women
9. Insight into DNA reprogramming during egg and sperm cell development
10. OHSU study shows that a molecule critical to nerve cells increases drammatically during hypertension
11. New risk factor identified for high blood pressure during pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... is available in German . ... method that uses the refraction of X-rays through a ... produced with this method are often of much higher ... the team of Prof. Franz Pfeiffer are particularly interested ... therapy including X-ray phase-contrast imaging. One main goal ...
(Date:7/11/2014)... The Chinese University of Hong Kong, BGI and other ... to salt tolerance, with implication for improving this important ... online in Nature Communications provides an effective ... , Soybean is an important crop for the world. ... less genetic diversities than their wild counterparts. Among the ...
(Date:7/11/2014)... including scientists from the Max Planck Institute for Medical ... step in understanding photosynthesis, the process by which the ... its atmosphere and which is therefore crucial for all ... researchers report the first direct visualization of a crucial ... which a specific protein complex, photosystem II, splits water ...
Breaking Biology News(10 mins):New simple setup for X-ray phase contrast 2BGI reports a novel gene for salt tolerance found in wild soybean 2A first direct glimpse of photosynthesis in action 2
... with nothing more than boots, a screen and a bucket, ... percent of the biomass in Tampa Bay now say they ... that led to the development of the modern-day human immune ... a key immune system protein that is similar to but ...
... the Public University of Navarre, Antonio Gerardo Pisabarro de ... genome of the oyster mushroom. The project research team ... centres from Europe, Canada, Japan, Israel and the United ... 400 entered for the annual competition of the Joint ...
... is that DNA and genes control everything of importance in ... , Increasingly, however, scientists are realizing that among the diverse ... DNA, many interact with each other and with genes directly ... , In particular, RNA produced by the vast stretches of ...
Cached Biology News:Tiny Tampa Bay fish key to evolution of immune system 2Tiny Tampa Bay fish key to evolution of immune system 3Sequencing of the oyster mushroom genome 2Sequencing of the oyster mushroom genome 3Sequencing of the oyster mushroom genome 4Peering into the shadow world of RNA 2Peering into the shadow world of RNA 3
(Date:7/11/2014)... , Not for release, publication or distribution (in ... where to do so would constitute a violation of the ... or the "Company") (LSE: SHP, NASDAQ: SHPG ) ... held a meeting with representatives of AbbVie. This ... or approval of AbbVie. A further update will ...
(Date:7/11/2014)... EPFL and the University of  Geneva  (UNIGE) ... P. Donoghue . The American neuroscientist is to head ... The new Wyss Center for Bio- and Neuro-Engineering, ... , has named as its director one of the ... founder of Brown University,s Institute for Brain Science, has ...
(Date:7/11/2014)... Cayenne Medical, Inc., a privately held ... tissue reconstruction segment, announced the worldwide launch of ... the shoulder and extremities. The SureLock System provides ... method. The unique delivery eliminates manual tensioning that ... anchor displacement (also commonly know as anchor “creep”). ...
(Date:7/10/2014)... 2014 Deep Knowledge Ventures last ... on ‘Commercialising Longevity Research’ and welcomed a host ... London Bioscience Innovation Center for the event, organised ... Analytics Ltd. The meeting highlighted the need for ... for age-related disease, as well as the crucial ...
Breaking Biology Technology:Shire plc - Statement re: Media Speculation 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 3Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 2DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 4DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 5DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 6
... N.C., Aug. 30, 2011 Savvier consumers and competition ... market entry or during brand maturity, more elusive.  At ... ability of cost-efficient Public Relations to support pharmaceutical brand ... Public Relations to support their brands, recent field research ...
... 30, 2011 Avantra Biosciences Corporation today announced ... to Courtagen Life Sciences, Inc.  The company will ... proteomics portfolio, which includes the Avantra Biomarker System. ... quantitative multiplex protein assays using catalog or custom ...
... Aug. 30, 2011 ProteinSimple today introduced a revolutionary new ... Simple Western is a complete reinvention of the Western Blot, ... the first time in 30 years, researchers have access to ... The Western Blot was invented in 1979 and to ...
Cached Biology Technology:Using Public Relations to Launch, Grow, and Extend Pharmaceutical and Biotech Brands 2ProteinSimple Reinvents the Western Blot 2
... controlled pre-amplifier suitable for a broad range ... for recording physiological signal such as ECG, ... input for use with a wide range ... include a stimulus artefact clamp to avoid ...
... be used with all 96-well ... stacking of covered plates ... with automated systems ... are available for use with ...
... Two sizes available for use with 96- or 384-well ... 96 for ease of location on 96-tube plates ... the skirt of the plate* Efficient sealing is ... in conjunction with screw or clip-down hot lid thermal ...
... Polystyrene covers can be used ... Ridged covers for stacking of ... covers for use with automated ... ridged and non-ridged, are available ...
Biology Products: