Professor Paul Elliott, the corresponding author of the research from the Department of Epidemiology and Public Health at Imperial College London, said: "Hypospadias is a condition that, if left untreated, can cause problems in later life. Although surgery to correct it is usually successful, any surgery will be traumatic for the child and his parents. It is encouraging that our study showed that taking folic acid supplements in pregnancy may reduce the risk of a child being born with the condition. Further research is needed to understand better why women exposed to hairspray at work in the first 3 months of pregnancy may have increased risk of giving birth to a boy with hypospadias."
The researchers reached their conclusions after conducting detailed telephone interviews with 471 mothers whose sons had been referred to surgeons for hypospadias and 490 controls, across 120 London Boroughs and Local Authority Districts.
The questionnaires explored a range of aspects of the women's health and lifestyle, including the mother's occupation and possible exposure to different chemical substances, family history of disease, maternal occupation, vegetarianism, smoking and use of folate supplements.
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| Contact: Laura Gallagher l.gallagher@imperial.ac.uk 44-020-759-48432 Imperial College London Source:Eurekalert |