Navigation Links
Hair provides proof of the link between chronic stress and heart attack

Researchers at The University of Western Ontario have provided the first direct evidence using a biological marker, to show chronic stress plays an important role in heart attacks. Stressors such as job, marital and financial problems have been linked to the increased risk for developing cardiovascular disease including heart attack. But there hasn't been a biological marker to measure chronic stress. Drs. Gideon Koren and Stan Van Uum developed a method to measure cortisol levels in hair providing an accurate assessment of stress levels in the months prior to an acute event such as a heart attack. The research is published on-line in the journal Stress.

Cortisol is considered to be a stress hormone. Its secretion is increased during times of stress. Traditionally it's been measured in serum, urine and saliva, but that only shows stress at the time of measurement, not over longer periods of time. Cortisol is also captured in the hair shaft.

"Intuitively we know stress is not good for you, but it's not easy to measure," explains Dr. Koren, who holds the Ivey Chair in Molecular Toxicology at Western's Schulich School of Medicine & Dentistry. "We know that on average, hair grows one centimetre (cm) a month, and so if we take a hair sample six cm long, we can determine stress levels for six months by measuring the cortisol level in the hair."

In the study, hair samples three cm long were collected from 56 male adults who were admitted to the Meir Medical Centre in Kfar-Saba, Israel suffering heart attacks. A control group, made up of 56 male patients who were hospitalized for reasons other than a heart attack, was also asked for hair samples. Higher hair cortisol levels corresponding to the previous three months were found in the heart attack patients compared to the control group.

The prevalence of diabetes, hypertension, smoking and family history of coronary artery disease did not differ significantly between the two groups, although the heart attack group had more cholesterol problems. After accounting for the known risk factors, hair cortisol content emerged as the strongest predictor of heart attack.

"Stress is a serious part of modern life affecting many areas of health and life," says Dr. Koren. "This study has implications for research and for practice, as stress can be managed with lifestyle changes and psychotherapy."

Contact: Kathy Wallis
519-661-2111 x81136
University of Western Ontario

Related biology news :

1. Paleozoic sediment curve provides new tool for tracking sea-floor sediment movements
2. Field Museum provides gold standard for mammal survey
3. Study provides insight on a common heart rhythm disorder
4. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
5. Brain structure provides key to unraveling function of bizarre dinosaur crests
6. MU brain imaging center provides research for autism, schizophrenia and Parkinsons disease
7. Supercomputer provides massive computational boost to biomedical research at TGen
8. Innovative surgery by MSU veterinarian provides new lease on life to dogs
9. New method provides panoramic view of protein-RNA interactions in living cells
10. Discovery of giant roaming deep sea protist provides new perspective on animal evolution
11. Rare disease provides clues about enzyme role in arrhythmias
Post Your Comments:
(Date:11/19/2015)... , Nov. 19, 2015  Based on its ... & Sullivan recognizes BIO-key with the 2015 Global Frost ... year, Frost & Sullivan presents this award to the ... catering to the needs of the market it serves. ... line meets and expands on customer base demands, the ...
(Date:11/18/2015)... 2015  As new scientific discoveries deepen our understanding ... healthcare providers face challenges in better using that knowledge ... addition, as more children continue to survive pediatric cancer, ... old age. John M. Maris, M.D ., ... Philadelphia (CHOP) . --> John M. ...
(Date:11/17/2015)... Paris from 17 th until ... from 17 th until 19 th November ... has invented the first combined scanner in the world which scans ... Until now two different scanners were required: one for passports ... on the same surface. This innovation is an ideal solution ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... , December 1, 2015 Partnership includes an ... for the u niversity , ... support treatment s cale - up ... (ARVs)   Africa , where licensees based anywhere in the ... on SDN technology. --> Africa , where licensees based anywhere ...
(Date:11/30/2015)... Mass. , Nov. 30, 2015 ... HART ), a biotechnology company developing bioengineered organ ... received written notification from The NASDAQ Stock Market ... bid price requirements. The letter noted that as ... HART,s common stock having exceeded $1.00 per share ...
(Date:11/30/2015)... BETHESDA, Md. , Nov. 30, 2015 /PRNewswire/ ... property development company committed to the fostering and ... on the current and prospective initiatives designed to ... , Chief Executive Officer of Spherix. "Based on ... potential future licensees exceeds $50 billion and Spherix ...
(Date:11/30/2015)... 30, 2015  Champions Oncology, Inc. (CSBR), engaged in ... personalize the development and use of oncology drugs, today ... will be presenting at the LD MICRO Investor Conference ... Time (PST).  The conference, held at the Luxe Sunset ... , will feature 200 small/micro-cap companies and is ...
Breaking Biology Technology: