Navigation Links
H1N1 pandemic points to vaccine strategy for multiple flu strains
Date:1/10/2011

, stalk-reactive antibody was thought to be very rare," Wrammert said. "In contrast, in the patients we studied, these stalk-reactive antibodies were surprisingly abundant."

The team tested whether three of their cross-reactive antibodies could protect mice against the 2009 strain or two other common lab strains. Two antibodies protected mice against an otherwise lethal dose of any of the three strains, even when the antibody was given 60 hours after infection.

One antibody, from the patient with the most severe illness, only protected against the 2009 H1N1 strain. The antibody genes from that patient suggest that the patient had a complete lack of preexisting immunity to H1N1 viruses. In cases where patients experienced a milder illness, it appears that immune cells that developed in response to previous seasonal flu shots or infections formed a foundation of response to 2009 H1N1 strain.

Although relatively few patients could be analyzed in detail at the antibody level, the authors conclude that "with the proper immunogen, the long-sought development of a pan-influenza vaccine might be possible."

Next, the research team is planning to examine the immune responses of people who were vaccinated against the 2009 H1N1 strain but did not get sick to see if they also produce antibodies that protect against many influenza strains.


'/>"/>

Contact: John Easton
john.easton@uchospitals.edu
773-702-6241
University of Chicago Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Rethinking who should be considered essential during a pandemic flu outbreak
2. Global Viral Forecasting Initiative receives $11M to implement pandemic early warning system
3. New World post-pandemic reforestation helped start Little Ice Age, say Stanford scientists
4. Swine flu genes dissimilar to past pandemics
5. 1 in 6 health workers wont report in flu pandemic -- study by Ben-Gurion U. researchers
6. K-State researcher, collaborators study virulence of pandemic H1N1 virus
7. Pandemic flu can infect cells deep in the lungs, says new research
8. Excellence in Paediatrics conference line-up includes WHO and CDC pandemic speakers
9. £7.5 million ($12.6 million) collaborations lead UK research communitys response to H1N1 pandemic
10. Short-term school closures may worsen flu pandemics, Pitt study finds
11. UT Southwestern scientist begins to unravel what makes pandemic H1N1 tick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... , Dec. 16, 2014 Research and Markets ... "Global Chemical Sensor Market 2015-2019" report to ... One major trend upcoming in this market ... applications. Chemical sensors help in recording of patient data ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... systems. Multimodal biometric systems utilize more than one characteristic ...
(Date:12/10/2014)... N.C. , Dec. 9, 2014  Valencell, a leader ... is seeing a staggering demand from its licensees for ... Company revealed, is not solely coming from fitness and ... well. "A wearable is only as useful ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... WASHINGTONA 110 million-year-old dinosaur that had a mouth that ... and nearly translucent skull bones will be unveiled Thursday, ... in the Sahara by National Geographic Explorer-in-Residence Paul Sereno, ... dinosaur is a plant eater known as Nigersaurus taqueti. ...
... will host the first annual meeting of the European ... Interactions, EUCAARI, headed by Academy Professor Markku Kulmala, on ... significantly improve current knowledge of the impact of fine ... The first year of the project was dedicated to ...
... 2007) -- In response to the need for localized ... the threatened staghorn coral, Diego Lirman, Ph.D., and James ... of Marine and Atmospheric Science (RSMAS) have established ... corals. The goals of the coral nursery are ...
Cached Biology News:Dinosaur from Sahara ate like a 'mesozoic cow' 2Dinosaur from Sahara ate like a 'mesozoic cow' 3Worldwide atmospheric measurements will determine the role of atmospheric fine particles 2New south Florida nursery to focus on staghorn corals 2
(Date:1/22/2015)... January 22, 2015 Eckert & Ziegler ... Spectrometry (AMS) services to the pharmaceutical and biotech industry, ... the company in the position of Director of Science ... broad and valuable experience in drug metabolism and bioanalysis ...
(Date:1/22/2015)... | RBJ today announces the firm brokered a long-term lease ... leading biopharmaceutical company, at Two Ledgemont Center in ... , president, and Brian Cohen , senior vice president, ... at 95 Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... 2015 Crystal Diagnostics (CDx) Xpress System, a ... received AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. ... referred to as STEC or the “Big-6”) as well as ... (cfu) per 325 g of raw ground beef and raw ...
(Date:1/22/2015)... January 22, 2015 Controlled Substance Compliance ... which helps companies check the legal requirements around using ... to China. , As their international operations expand ... adopting software solutions built as a result of the ...
Breaking Biology Technology:Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 2Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 3Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Global Compliance Service for Controlled Substances to Expand to China 2
... Virginia, September 9 Biovista Inc.,today announced that BVA-201, ... results in the MOG-induced Experimental Allergic,Encephalomyelitis (EAE) murine model ... in MS and is aimed at neuroprotection. It was ... toxic effects in this well,established model of MS. , ...
... ISELIN, N.J., Sept. 9 SyntheMed, Inc. ... the development and commercialization of anti-adhesion products, announced today ... the reduction of adhesions following cardiac surgery, has received ... in all patients who undergo open-heart surgery. REPEL-CV ...
... , DURHAM, N.C., Sept. 9 Oxygen ... which is being mailed today, asks shareholders to approve a 1-for-15 ... , , "At last years, general annual meeting ... the bulletin board and we promised to seek a listing change ...
Cached Biology Technology:Biovista Inc. Announces Positive Efficacy Results in a Pre-clinical Trial of its BVA-201 Repositioned Drug for Multiple Sclerosis 2SyntheMed Receives Brazilian Regulatory Approval for REPEL-CV(TM) 2Oxygen Biotherapeutics, Inc. Seeks Shareholder Approval for Reverse Stock Split 2
Request Info...
... EPS 3501 XL Power Supply, 1. ... voltage, constant current, constant power, and linear ... proteins to focused equilibrium in IPG strips ... modes compensate for variations in gel thickness, ...
MOUSE ANTI BOVINE CD335:ALEXA 488 Immunogen: Fusion protein consisting of the extracellular region of bovine CD335....
... Complete Derivation Kit is intended for ... from delayed blastocysts in serum-free conditions. ... Clonal Grade Medium ... Incubation Medium Trypsin Solution Gelatin ...
Biology Products: