Navigation Links
Gutsy germs succumb to baby broccoli
Date:4/5/2009

blished April 6 in Cancer Prevention Research, builds on earlier test-tube and mouse studies at Johns Hopkins and elsewhere about the potential value of sulforaphane, a naturally occurring biochemical found in relative abundance in fresh broccoli sprouts. (http://www.hopkinsmedicine.org/press/2002/may/020528.htm) Sulforaphane appears to trigger cells in the body, including in the gastrointestinal tract, to produce enzymes that protect against oxygen radicals, DNA-damaging chemicals, and inflammation.

In the new report, the team also shows that when H. pylori-infected mice sipped broccoli-sprout smoothies for eight weeks, there was up to a fourfold increase in the activity of two of these key enzymes that protect cells against oxidative damage. In addition, the number of Helicobacter bacteria in the mice's stomachs decreased by almost a hundredfold it did not change in infected control animals that drank plain water. The researchers also noted a greater than 50 percent reduction in inflammation of the primary target of this bacterium the body of the stomach in treated mice but not in controls.

In a related experiment, the team fed the same dose of broccoli sprouts for the same amount of time to H. pylori-infected mice that had been genetically engineered to lack the Nrf2 gene that activates protective enzymes. "These knock-out mice didn't respond," Fahey says, which confirms previous findings for a role of Nrf2 in protection against H. pylori-induced inflammation and gastritis.

Classified a carcinogen by the World Health Organization, H. pylori is a gastrointestinal tract germ that manages to thrive in the lining of the stomach despite the strength of natural acids there that rival that of car batteries. Afflicting several billion people roughly half of the world's population this corkscrew-shaped bacterium has long been associated
'/>"/>

Contact: Maryalice Yakutchik
myakutc1@jhmi.edu
443-287-2251
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Dog owners more likely to share germs with pets by not washing hands than by sleeping with dog
2. Honeybees succumb to cocaines allure
3. Extract of broccoli sprouts may protect against bladder cancer
4. Natural compound in broccoli could treat devastating genetic skin disorder
5. Natural chemical found in broccoli helps combat skin blistering disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2015)... 13, 2015  higi, a leading cloud-based consumer engagement ... fully engage with their communities around health and wellness, ... and secure API.  ... accessible, affordable, and convenient vehicle to receive validated health ... The API will allow higi,s trusted partners, ...
(Date:4/2/2015)... April 2, 2015 In ... by far outperforms the strongest competitors, showing outstanding ... accuracy, the system is capable of a throughput ... proves up to be ten times faster than ... runner-up performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
(Date:4/1/2015)... April 1, 2015   Medisafe ™, the leading ... across iOS and Android smartphones ... biofeedback into the platform to allow patients to track ... the first time, patients will be able to visualize ... impacts important biometrics, such as glucose levels and blood ...
Breaking Biology News(10 mins):higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2
... A healthy Nordic diet lowers cholesterol levels, and therefore ... Lund University participated has found. There was also decreased ... who ate a Nordic diet had lower levels of ... cholesterol. The amount of harmful fat particles in the ...
... microplastic pollution in one of Western Europe,s largest lakes, Lake ... in the ocean have shown that these small bits of ... on plankton or other small waterborne organisms, the full extent ... being investigated. The study, which is being extending under a ...
... for Infection and Immunity at Columbia University,s Mailman School ... Viral Disease Control and Prevention (NIVDC) within the Chinese ... Joint Research Laboratory for Pathogen Discovery to conduct surveillance, ... and develop drugs and vaccines to treat diseases in ...
Cached Biology News:Microplastic pollution prevalent in lakes too 2Microplastic pollution prevalent in lakes too 3Unique US-Chinese lab to head off H7N9 outbreak and future threats 2
(Date:4/23/2015)... , April 23, 2015  Cryoport, Inc. (OTCBB: ... logistics solutions for the life sciences industry, today ... cryogenic logistics solutions within the animal husbandry market ... Farms to support the shipment of equine semen ... horse Stallions. Animal husbandry is ...
(Date:4/23/2015)... -- Metanome, Inc., an industry leader in comprehensive microbiome ... name to Diversigen, Inc.  The name was changed ... source for the myriad of services and expertise ... of the microbiome.  From the wide diversity in ... that are difficult to handle, such as low ...
(Date:4/22/2015)...  The Heinz Family Foundation today announced the ... which will present unrestricted cash awards totaling $1.25 ... and determination in finding solutions to critical issues ... recipients include a prolific cartoonist whose quirky characters ... relationships; two former Marines who are re-engaging veterans ...
(Date:4/22/2015)... , April 22, 2015 Steep ... analytics, announced today that it has opened an ... continued growth and expansion.  The common stock investment ... Section 506(c), a law intended to encourage funding ... Prior to 506(c), small businesses largely relied on ...
Breaking Biology Technology:Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Metanome Announces Corporate Name Change to Diversigen 2From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 2From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 3From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 4From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 5From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 6Steep Hill Launches $5M Limited Stock Offering 2Steep Hill Launches $5M Limited Stock Offering 3
... Internet service provider, recently added a third OC12 connection ... services to businesses in outlying communities that previously have ... Charter Business Networks expands SupraNets capabilities to ... state where Charter has a fiber presence. The expanded ...
... Wis. Fiserv Imagesoft , a unit of ... disaster recovery services offering for its clients that ... suite. , ,The new multiple-option service is designed ... processing function quickly, without interruption, after virtually any ...
... can create organic growth (or growth other than by acquisition). ... Rubbermaid , which launches a new product every day. ... new markets. The most difficult kind of development and launch ... is a new product into an existing market (because your ...
Cached Biology Technology:Rural Wisconsin businesses gain high-speed net access 2Seven reasons new technology product development goes astray 2Seven reasons new technology product development goes astray 3Seven reasons new technology product development goes astray 4
... Proteolytic degradation is critical to ... short-lived and regulatory proteins as important ... cellular metabolism, heat shock and stress ... surface receptors and ion channels, cell ...
... Proteolytic degradation is critical to ... short-lived and regulatory proteins as important ... cellular metabolism, heat shock and stress ... surface receptors and ion channels, cell ...
... LIBS2000+ Spectrometers (sold separately) in the New ... to offer numerous configuration options and precise ... a high-power 1064 nm Nd:YAG laser, sample ... positioning, laser spot diameter control from 20 ...
... Picking,A modified digital scanner serves as the ... the five standard rack positions on the ... micro well plates on the remaining two ... single spots by mouse-click on the scanned ...
Biology Products: