Navigation Links
Gut microbes closely linked to proper immune function, other health issues
Date:9/16/2013

CORVALLIS, Ore. -- A new understanding of the essential role of gut microbes in the immune system may hold the key to dealing with some of the more significant health problems facing people in the world today, Oregon State University researchers say in a new analysis.

Problems ranging from autoimmune disease to clinical depression and simple obesity may in fact be linked to immune dysfunction that begins with a "failure to communicate" in the human gut, the scientists say. Health care of the future may include personalized diagnosis of an individual's "microbiome" to determine what prebiotics or probiotics are needed to provide balance.

Appropriate sanitation such as clean water and sewers are good. But some erroneous lessons in health care may need to be unlearned -- leaving behind the fear of dirt, the love of antimicrobial cleansers, and the outdated notion that an antibiotic is always a good idea. We live in a world of "germs" and many of them are good for us.

"Asked about their immune system, most people might think of white blood cells, lymph glands or vaccines," said Dr. Natalia Shulzhenko, author of a new report in Clinical Reviews in Allergy and Immunology, and assistant professor and physician in the OSU Department of Biomedical Sciences. "They would be surprised that's not where most of the action is. Our intestines contain more immune cells than the entire rest of our body.

"The human gut plays a huge role in immune function," Shulzhenko said. "This is little appreciated by people who think its only role is digestion. The combined number of genes in the microbiota genome is 150 times larger than the person in which they reside. They do help us digest food, but they do a lot more than that."

An emerging theory of disease, Shulzhenko said, is a disruption in the "crosstalk" between the microbes in the human gut and other cells involved in the immune system and metabolic processes.

"In a
'/>"/>

Contact: Dr. Natalia Shulzhenko
Natalia.shulzhenko@oregonstate.edu
541-737-1051
Oregon State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Toxic methylmercury-producing microbes more widespread than realized
2. Scientists discover thriving colonies of microbes in ocean plastisphere
3. New palm-sized microarray technique grows 1,200 individual cultures of microbes
4. Engineered microbes grow in the dark
5. Microbes capture, store, and release nitrogen to feed reef-building coral
6. The microbes you inhale on the New York City subway
7. Measuring microbes makes wetland health monitoring more affordable, says MU researcher
8. Blood vessels sniff gut microbes to regulate blood pressure
9. The lifetime journeys of manure-based microbes
10. Microbes team up to boost plants stress tolerance
11. Gut microbes could determine the severity of melamine-induced kidney disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... Kent has shown for the first time how the ... could have a major impact on cancer therapy development. ... the mechanism whereby the physical properties of the internal ... are ,fine-tuned, to undertake different functions. , While some ... a framework for the cell, others are more dynamic, ...
(Date:7/29/2014)... babies latest research from the University of Adelaide ... brains of many preterm children can perform almost as well ... the University,s Robinson Research Institute has found that ... in early life, their cognitive abilities as a teenager can ... the results of the study, published in this month,s issue ...
(Date:7/29/2014)... different types of cell, including sperm, bacteria and ... flagella. These protrusions, about one-hundredth of a millimetre ... through fluid. Similar, shorter structures called cilia are ... they perform roles such as moving liquids over ... remarkably versatile: they transport mucus and expel pathogens ...
Breaking Biology News(10 mins):Preterm children's brains can catch up years later 2Microscopic rowing -- without a cox 2Microscopic rowing -- without a cox 3
... When faced with cancer, the immune system dispatches cells, called ... often fail to completely eliminate the tumor because theyre deactivated ... T cells. Past attempts to get rid of these regulatory ... many features with the killer T cells, making it difficult ...
... Black carbon, a form of particulate air pollution most ... and diesel exhaust, has a warming effect in the ... according to scientists in an upcoming review article in ... at UC San Diego atmospheric scientist V. Ramanathan and ...
... the Wellcome Trust has provided a number of promising ... Scientists at the University of Cambridge have identified a ... cells to "eat" the malformed proteins that lead to ... number of degenerative diseases marked by build up of ...
Cached Biology News:Black carbon pollution emerges as major player in global warming 2Black carbon pollution emerges as major player in global warming 3Promising new drug targets identified for Huntington's disease 2
(Date:7/29/2014)... July 29, 2014  The Society for Clinical ... updated program for the 9 th annual ... in Amelia Island , Florida.  The focus ... remains unchanged, however, the topics and format will ... opportunity among all stakeholders with a continued focus ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 Second generation biofuels ... imposed by fossil fuels. However, as natural gas is very ... as they are not as valuable as they could be ... the difficulty financing projects, has made it difficult for renewable ... projects get off the ground. For these reasons, certain companies ...
(Date:7/29/2014)... July 29, 2014  Discovery Laboratories, Inc. (Nasdaq: ... a new standard of respiratory critical care, will report ... 5, 2014 before the open of the U.S. ... host a live teleconference and webcast at 9:00 a.m. ... call, Discovery Labs, management will discuss the 2014 ...
(Date:7/29/2014)... 29, 2014 A new report ... (types, applications and geography) - Size, Share, Global Trends, ... and Forecast, 2013 - 2020", suggests that the global ... by 2020 registering a CAGR of 11.1% from 2014 ... by the electro surgical devices in operative procedures by ...
Breaking Biology Technology:TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 2TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 3Renewable Waste Intelligence: Could Renewable Chemicals Be the Future for the Renewable Energy Industry? 2Discovery Labs to Report 2014 Second Quarter Financial Results and Hold Conference Call on Tuesday, August 5, 2014 at 9:00 a.m. Eastern Time 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 3
... TRANSPORTATION -- Gone hybrid . . . ... automobiles are now posted at the www.fueleconomy.gov web ... the U.S. Department of Energy and the U.S. Environmental Protection ... fuel economy list are hybrid electrics, led by the Toyota ...
... , WELLINGTON, Colo., Nov. 5 The endangered black-footed ferrets ... rare carnivore feeds on prairie dogs. The prairie ... die-offs in towns occur. The U.S. Fish & Wildlife ... been releasing trained, captive ferrets into their formerly native habitat. ...
... Imagenetix, Inc. (OTC Bulletin Board: IAGX), announced today that ... the Company,s story at the 2nd annual LD MICRO Conference ... Luxe Sunset in Los Angeles. , About LD MICRO , ... on finding undervalued companies in the micro-cap space. Since 2002, ...
Cached Biology Technology:November 2009 story tips from the US Department of Energy's Oak Ridge National Laboratory 2November 2009 story tips from the US Department of Energy's Oak Ridge National Laboratory 3Colorado Companies Team Up With U.S. Fish & Wildlife Service to Protect Black-Footed Ferret 2Imagenetix to Present at 2nd Annual LD MICRO Conference at the Luxe Sunset Bel Air 2
... refrigerators, freezers, or liquid nitrogen. Conveniently sized to fit ... coding to project, user, lab, etc. Holes in the ... circulation. Supplied with 9 x 9 (12.7 mm cell) ... 13 x 13 x 5.1 cm H (5 1/4 ...
Recombinant Rhesus Monkey IFN-Alpha...
Homo sapiens HCLS1 associated protein X-1 Antigen: Recombinant Protein...
5,6 Carboxyfluorescein is conjugated to BSA (bovine serum albumin) protein through amide bonds....
Biology Products: