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Gut microbes battle a common set of viruses shared by global populations
Date:6/24/2012

y found that nearly 80% of the phages are shared between two or more individuals. The team compared their data to samples previously derived from American and Japanese individuals, finding phages from their European data set also present in these geographically distant populations, a surprising result given the diversity of phages seen in other ecological niches.

Sorek explained that their findings mean that there are hundreds of types of viruses that repeatedly infect our gut microbiota. "These viruses can kill some of our gut bacteria," said Sorek. "It is therefore likely that these viruses can influence human health."

The authors note that as evidence for the beneficial roles played by bacteria in the healthy human gut continues to mount, it is critical that we understand the pressures placed upon the "good" bacteria that are vital to human health. "Our discovery of a large set of phages attacking these good bacteria in our gut opens a window for understanding how they affect human health," Sorek added. Researchers can now begin to ask how phage dynamics in the gut changes over time, and what it might tell us about diseases, such as inflammatory bowel disease, and how to more effectively treat them.

Scientists from the Weizmann Institute of Science (Rehovot, Israel) and Tel Aviv University (Tel Aviv, Israel) contributed to this study.


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Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4013
Cold Spring Harbor Laboratory
Source:Eurekalert

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