Navigation Links
Guang Yue, Ph.D., of Kessler Foundation awarded NIH grant for cancer rehabilitation research
Date:10/6/2014

West Orange, NJ. October 6, 2014. Guang Yue, PhD, of Kessler Foundation has been awarded an NIH grant for$1,962,767 to study the impact of high-effort training on the muscle weakness that impairs quality life among many individuals with cancer. Dr. Yue is the Foundation's director of Human Performance & Engineering Research. This 5-year RO1 grant will enable him to pursue his preliminary findings that indicate that high-effort combined with low-intensity muscle exercise training can significantly improve muscle strength in women with breast cancer.

Weakness limits mobility and diminishes quality of life in many cancer survivors, especially in those with late-stage cancer. Participating in high-intensity strength training is difficult and unsafe in patients with limited physical abilities. Recent evidence in healthy adults shows that training with high effort (intended muscle contraction) combined with minimal physical exercise increases brain-to-muscle command, which helps improve motor unit recruitment and activation level resulting in muscle strengthening (a motor unit is consisted of a motor neuron in the spinal cord and muscle fibers it controls). These observations led Dr. Yue and colleagues to hypothesize that training-induced voluntary strength gain relies on level of effort rather than the intensity of physical exercise.

"Our major goal is to test this hypothesis by training women with breast cancer-related weakness using high effort plus moderate intensity exercise vs low effort combined with moderate intensity muscle exercise," said Dr. Yue. "Using strength testing and specialized EEG and neuroimaging techniques, we will look at the effects on handgrip strength and the level of functional brain-to-brain and brain-to-muscle connectivity that modulates maximal muscle force. What we discover about voluntary muscle strengthening is likely to be applicable to other patient populations or frail older adults who suffer muscle weakness."


'/>"/>

Contact: Carolann Murphy
cmurphy@kesslerfoundation.org
973-324-8382
Kessler Foundation
@KesslerFound
Source:Eurekalert  

Related biology news :

1. Effect of repeated-pulse transcranial magnetic stimulation at the Guangming point on EEGs
2. Pioneer Award recipients Robin Ali, Ph.D., Jean Bennett, M.D., Ph.D., and William Hauswirth, Ph.D.
3. Simon Levin, Ph.D., awarded prestigious 2014 Tyler Prize for Environmental Achievement
4. Jackson Laboratory researcher Gareth Howell, Ph.D., receives Lewis Rudin Glaucoma Prize
5. Joseph Glorioso, Ph.D., receives Pioneer Award
6. The American Society of Hematology honors Andrew S. Weyrich, Ph.D., with 2013 William Dameshek Prize
7. Kessler Foundation researchers find foot drop stimulator beneficial in stroke rehab
8. Kessler Foundation researchers publish first study of brain activation in MS using fNIRS
9. Kessler Foundation awarded Department of Defense grant for spinal cord injury research
10. Kessler Foundation researchers study impact of head movement on fMRI data
11. Kessler Foundation neuroimaging study sheds light on mechanisms of cognitive fatigue in MS
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Guang Yue, Ph.D., of Kessler Foundation awarded NIH grant for cancer rehabilitation research
(Date:6/14/2019)... ... June 14, 2019 , ... Molecular diagnostics segment is the fastest-growing ... million in 2019. Major segments that are expected to drive the growth are ... and forecasted as segments in Kalorama’s The World Molecular Diagnostics Market, 8th Edition ...
(Date:6/6/2019)... ... June 05, 2019 , ... MedTech Breakthrough , ... health and medical technology market, announced that it has selected Medacta International’s MySpine® ... award in the 2019 MedTech Breakthrough Awards program. , Medacta® ...
(Date:6/4/2019)... ... June 04, 2019 , ... Harper was three years old when her owners ... dysplasia, which caused painful osteoarthritis in the joints. She was referred to a ... , The surgical specialist, Dr. Christopher Eich of Southern California Veterinary Specialty Hospital ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... (PRWEB) , ... May 30, 2019 , ... ... the first to demonstrate an efficient delivery system for the sustained release of ... The platelet-rich plasma-based gel system was able to deliver CM into the injured ...
(Date:5/14/2019)... ... May 13, 2019 , ... Leak Detection ... for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries’ is excited to ... aims to improve LDA’s ability to communicate directly with the marketplace; serving as ...
(Date:5/4/2019)... ... 03, 2019 , ... Diopsys Inc, the world leader in ... vision test, a new full field electroretinography (ffERG) protocol designed to detect ... Americans will have glaucoma, with black Americans having the highest prevalence rate. This ...
(Date:5/2/2019)... ... May 02, 2019 , ... Boston ... greater Boston area. Gone are the days of painful hair transplant procedures. Boston ... Restoration System is the only robotic intelligent solution to offer a minimally invasive ...
Breaking Biology Technology: